Clinical Trials Browser

NIH × Colonic Neoplasms × Fluorouracil × Clear all

NCT00217737 2026-05-26

Oxaliplatin, Leucovorin, and Fluorouracil With or Without Bevacizumab in Treating Patients Who Have Undergone Surgery for Stage II Colon Cancer

Phase 3 Active not recruiting

2,431 enrolled 13 charts

Gastrointestinal

Colonic Neoplasms

NCT02912559 2026-05-05

Combination Chemotherapy With or Without Atezolizumab in Treating Patients With Stage III Colon Cancer and Deficient DNA Mismatch Repair

Phase 3 Active not recruiting

712 enrolled 14 charts

Gastrointestinal

Colonic Neoplasms, Colorectal Neoplasms, Hereditary Nonpolyposis, DNA Repair-Deficiency Disorders

NCT00079274 2020-05-13

Comparison of Combination Chemotherapy Regimens With or Without Cetuximab in Treating Patients Who Have Undergone Surgery For Stage III Colon Cancer

Phase 3 Completed

3,397 enrolled 24 charts

Gastrointestinal

Colonic Neoplasms

NCT00096278 2019-07-30

Fluorouracil, Leucovorin, and Oxaliplatin With or Without Bevacizumab in Treating Patients Who Have Undergone Surgery for Stage II or Stage III Colon Cancer

Phase 3 Completed

2,710 enrolled 8 charts

Gastrointestinal

Colonic Neoplasms

NCT01383343 2017-04-19

Sorafenib Tosylate, Bevacizumab, Irinotecan Hydrochloride, Leucovorin Calcium, and Fluorouracil in Treating Patients With Metastatic Colorectal Cancer

Phase 1 Completed

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms

NCT01270438 2017-04-04

Combination Chemotherapy and Bevacizumab With or Without RO4929097 in Treating Patients With Metastatic Colorectal Cancer

Phase 2 Withdrawn

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms

NCT00004547 2015-11-18

Treatment of Peritoneal Cancer With Surgery, Perfused Heated Cisplatin and Chemotherapy

Phase 2 Completed

188 enrolled 11 charts

GastrointestinalGynecologicOther solid neoplasmThoracic

Abdominal Neoplasms, Colonic Neoplasms, Mesothelioma, Peritoneal Neoplasms

NCT00100841 2015-07-27

Phase II Trial of FOLFOX6, Bevacizumab and Cetuximab in Patients With Colorectal Cancer

Phase 2 Completed

66 enrolled 7 charts

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms

NCT00499369 2014-07-31

Irinotecan and Cetuximab With or Without Bevacizumab in Treating Patients With Metastatic Colorectal Cancer That Progressed During First-Line Therapy

Phase 3 Terminated

72 enrolled 15 charts

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms

NCT00008281 2014-01-06

Comparison of Three Chemotherapy Regimens in Treating Patients With Metastatic Colorectal Cancer

Phase 3 Unknown

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00027833 2014-01-06

Vaccine Therapy and Chemotherapy With or Without Tetanus Toxoid Compared With Chemotherapy Alone in Treating Patients With Metastatic Colorectal Cancer

Phase 2 Unknown

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00002692 2013-12-19

Intravenous Compared With Intrahepatic Chemotherapy in Treating Patients With Colorectal Cancer Metastatic to the Liver

Phase 3 Unknown

Gastrointestinal

Colonic Neoplasms, Neoplasm Metastasis, Rectal Neoplasms, Colorectal Neoplasms

NCT00002893 2013-12-19

Palliative Chemotherapy in Treating Patients With Advanced Colorectal Cancer

Phase 3 Unknown

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00008060 2013-12-19

Combination Chemotherapy in Treating Patients With Unresectable Metastatic Colorectal Cancer

Phase 3 Completed

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00021281 2013-12-19

Combination Chemotherapy With or Without SU5416 in Treating Patients With Metastatic Colorectal Cancer

Phase 3 Unknown

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00408551 2013-12-19

Chemotherapy and Internal Radiation in Treating Patients With Colorectal Cancer That Has Spread to the Liver

Phase 2 Unknown

Gastrointestinal

Colonic Neoplasms, Neoplasm Metastasis, Rectal Neoplasms, Colorectal Neoplasms

NCT00975897 2013-12-19

Study of Tumor Tissue Testing in Selecting Treatment for Patients With Metastatic or Locally Advanced Colorectal Cancer

Phase 2/3 Completed

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00005586 2013-12-18

Leucovorin and Fluorouracil Compared With Observation in Treating Patients With Colorectal Cancer That Has Been Surgically Removed

Phase 3 Completed

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00004150 2013-11-06

High-Dose Fluorouracil With or Without Leucovorin Compared With Standard Fluorouracil Plus Leucovorin Following Surgery in Treating Patients With Stage III Colon Cancer

Phase 3 Completed

Gastrointestinal

Colonic Neoplasms, Colorectal Neoplasms

NCT00062426 2013-11-06

Oxaliplatin and Bevacizumab (Avastin™) With Either Fluorouracil and Leucovorin or Capecitabine in Treating Patients With Advanced Colorectal Cancer

Phase 3 Completed

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00003835 2013-10-08

Combination Chemotherapy in Treating Patients With Stage III Colon Cancer

Phase 3 Completed

Gastrointestinal

Colonic Neoplasms

NCT00060411 2013-09-30

A Phase I, Pharmacological, and Biological Study of OSI-774 in Combination With FOLFOX 4 (5-FU, Leucovorin, and Oxaliplatin) and Bevacizumab (Avastin) in Patients With Advanced Colorectal Cancer

Phase 1 Completed

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms

NCT00138177 2013-09-30

Suberoylanilide Hydroxamic Acid, Fluorouracil, Leucovorin, and Oxaliplatin in Treating Patients With Progressive Metastatic or Unresectable Colorectal Cancer or Other Solid Tumors

Phase 1 Completed

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms

NCT00003063 2013-09-20

Biological Therapy With Combination Chemotherapy in Patients With Colorectal Cancer

Phase 3 Unknown

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00016042 2013-09-20

Fluorouracil and Biological Therapy in Treating Patients With Metastatic Kidney or Colorectal Cancer

Phase 1 Unknown

GastrointestinalGenitourinary

Carcinoma, Renal Cell, Colonic Neoplasms, Kidney Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00046995 2013-09-20

Combination Chemotherapy in Treating Patients With Colon Cancer

Phase 3 Unknown

Gastrointestinal

Colonic Neoplasms, Colorectal Neoplasms

NCT00002793 2013-09-17

Chemotherapy Via an Implantable Pump Compared With a Subcutaneous Port for Unresectable Liver Metastases in Patients With Resected Colorectal Cancer

Phase 3 Unknown

Gastrointestinal

Colonic Neoplasms, Neoplasm Metastasis, Rectal Neoplasms, Colorectal Neoplasms

NCT00182715 2013-09-17

Combination Chemotherapy With or Without Cetuximab as First-Line Therapy in Treating Patients With Metastatic Colorectal Cancer

Phase 3 Unknown

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00797485 2013-08-26

Bevacizumab and Combination Chemotherapy in Treating Patients With Previously Untreated Metastatic Colorectal Cancer That Cannot Be Removed By Surgery

Phase 3 Unknown

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00003446 2013-06-26

Chemotherapy in Treating Patients With Recurrent or Metastatic Colorectal Cancer

Phase 2 Completed

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00016198 2013-06-26

Fluorouracil and Leucovorin With or Without Oxaliplatin in Treating Patients With Recurrent Metastatic Colorectal Cancer

Phase 2 Completed

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00030342 2013-06-26

Biological Therapy and Chemotherapy in Treating Patients With Metastatic Kidney Cancer or Colorectal Cancer

Phase 1/2 Completed

GastrointestinalGenitourinary

Carcinoma, Renal Cell, Colonic Neoplasms, Kidney Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00006786 2013-06-24

Combination Chemotherapy Plus Bevacizumab in Treating Patients With Advanced Colorectal Cancer

Phase 2 Completed

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00049101 2013-06-24

Erlotinib and Combination Chemotherapy in Treating Patients With Metastatic Colorectal Cancer

Phase 1/2 Completed

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00427570 2013-06-24

Fluorouracil, Semustine, and Vincristine Compared With BCG in Treating Patients With Dukes' B or Dukes' C Colon Cancer That Has Been Removed By Surgery

Phase 3 Completed

Gastrointestinal

Colonic Neoplasms, Colorectal Neoplasms

NCT00039611 2013-06-20

Combination Chemotherapy in Treating Patients With Advanced Colorectal Cancer

Phase NA Completed

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00066846 2013-06-20

Bevacizumab Plus Fluorouracil and Leucovorin in Treating Patients With Locally Advanced or Metastatic Stage IV Colorectal Cancer That Has Progressed After Standard Chemotherapy

Phase 2 Completed

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00103298 2013-06-20

Isolated Hepatic Perfusion With Melphalan Followed by Combination Chemotherapy in Treating Patients With Unresectable Liver Metastases From Colorectal Cancer

Phase 2 Completed

Gastrointestinal

Colonic Neoplasms, Neoplasm Metastasis, Rectal Neoplasms, Colorectal Neoplasms

NCT00016133 2013-05-30

Vaccine Therapy in Treating Patients With Stage II or Stage III Colon Cancer That Has Been Removed During Surgery

Phase 1/2 Completed

Gastrointestinal

Colonic Neoplasms, Colorectal Neoplasms

NCT00025142 2013-05-15

Gefitinib and Combination Chemotherapy in Treating Patients With Advanced Solid Tumors or Colorectal Cancer

Phase 2 Completed

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00005036 2013-05-03

Irinotecan Compared With Combination Chemotherapy in Treating Patients With Advanced Colorectal Cancer

Phase 3 Completed

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms

NCT00006015 2013-05-03

Combination Chemotherapy Plus Trastuzumab in Treating Patients With Advanced, Recurrent, or Metastatic Colorectal Cancer

Phase 2 Terminated

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00026364 2013-03-21

ZD 1839 Plus Combination Chemotherapy in Treating Patients With Locally Advanced, Locally Recurrent, or Metastatic Colorectal Cancer

Phase 1 Completed

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00016978 2013-02-05

Combination Chemotherapy in Treating Patients With Metastatic Colorectal Cancer Previously Treated With Irinotecan

Phase 2 Completed

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00002796 2013-02-01

Phase I-II Study of Fluorouracil in Combination With Phenylbutyrate in Advanced Colorectal Cancer

Phase 1/2 Terminated

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms

NCT00070122 2013-01-25

Combination Chemotherapy and Bevacizumab in Treating Patients With Locally Advanced, Metastatic, or Recurrent Colorectal Cancer

Phase 3 Terminated

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms

NCT00003873 2013-01-24

Fluorouracil With or Without Eniluracil in Treating Patients With Advanced Colorectal Cancer

Phase 3 Completed

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms

NCT00025337 2013-01-24

Combination Chemotherapy With or Without Bevacizumab Compared With Bevacizumab Alone in Treating Patients With Advanced or Metastatic Colorectal Cancer That Has Been Previously Treated

Phase 3 Completed

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms

NCT00052585 2013-01-16

Gefitinib and Combination Chemotherapy in Treating Patients With Advanced or Recurrent Colorectal Cancer

Phase 2 Terminated

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms

NCT00004931 2013-01-14

Fluorouracil Plus Leucovorin With or Without Oxaliplatin in Treating Patients With Stage II or Stage III Colon Cancer

Phase 3 Completed

Gastrointestinal

Colonic Neoplasms