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Phase

Phase 1 1

Status

Completed 2Withdrawn 1Terminated 1

Sponsor Class

OTHER 1

Study Type

Interventional 1

Sponsor

Cancer Type

Gastrointestinal 1

Conditions

Prostatic Neoplasms 8Polycystic Ovary Syndrome 7Carcinoma, Non-Small-Cell Lung 6Breast Neoplasms 6Colorectal Neoplasms 5Lung Neoplasms 4Metabolic Syndrome 3Insulin Resistance 3Adenocarcinoma of Lung 3Lymphoma, Large B-Cell, Diffuse 2Glioblastoma 2Carcinoma, Renal Cell 2pCR Rate 1Weight Gain 1Thyroid Diseases 1Thoracic Neoplasms 1Squamous Cell Carcinoma of Head and Neck 1Rectal Neoplasms 1Precursor Cell Lymphoblastic Leukemia-Lymphoma 1Pancreatic Neoplasms 1Obesity 1Non-alcoholic Fatty Liver Disease 1Neoplasms 1Neoplasm Metastasis 1Mouth Neoplasms 1Motor Activity 1Melanoma 1Lymphoma 1Leukoplakia 1Leukemia, Myelomonocytic, Acute 1

Interventions

Fluorouracil 25Oxaliplatin 24Irinotecan 24Leucovorin 23Bevacizumab 23Capecitabine 18Cetuximab 15Radiotherapy 6Gene Expression Profiling 5regorafenib 4Immunohistochemistry 4Gemcitabine 4Folfox protocol 4Colonoscopy 4Cisplatin 4Celecoxib 4Amplified Fragment Length Polymorphism Analysis 4Reverse Transcriptase Polymerase Chain Reaction 3Receptor Protein-Tyrosine Kinases 3Polymerase Chain Reaction 3Nivolumab 3Mitomycin 3Doxorubicin 3Cyclophosphamide 3Cholecalciferol 3Biopsy 3Aspirin 3sargramostim 2pembrolizumab 2ixabepilone 2

Date Range

30 days90 days1 yearAll

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Clinical Trials

1 trials
RecentStart dateEnrollment
Terminated × Colonic Neoplasms × Metformin × Clear all
NCT01440127 2015-03-26

Impact of Pretreatment With Metformin on Colorectal Cancer Stem Cells (CCSC) and Related Pharmacodynamic Markers

Tufts Medical Center

Phase 1 Terminated
9 enrolled
Gastrointestinal

Colonic Neoplasms

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