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Phase

Phase 1 1

Status

Completed 2Terminated 1Recruiting 1Not yet recruiting 1Active not recruiting 1

Sponsor Class

INDUSTRY 1

Study Type

Interventional 1

Sponsor

Cancer Type

Thoracic 1Gynecologic 1Gastrointestinal 1

Conditions

Carcinoma, Non-Small-Cell Lung 68Lung Neoplasms 18Neoplasms 7Neoplasm Metastasis 7Melanoma 5Carcinoma 5Mesothelioma, Malignant 4Colorectal Neoplasms 4Parkinson Disease 4, Autosomal Dominant Lewy Body 3Ovarian Neoplasms 3Carcinoma, Transitional Cell 3Squamous Cell Carcinoma of Head and Neck 2Pancreatic Neoplasms 2Non-Squamous Non-small Cell Lung Cancer 2Non-Small Cell Lung Cancer Metastatic 2Non Small Cell Lung Carcinoma NSCLC 2Mesothelioma 2Endometrial Neoplasms 2Brain Neoplasms 2Advanced Solid Tumors 2Uveal Melanoma 1Uterine Cervical Neoplasms 1Stomach Neoplasms 1Solitary Fibrous Tumor, Pleural 1Salivary Gland Neoplasms 1Resectable Stage IIA to IIIB Non-small Cell Lung Cancer 1Resectable Non-small Cell Lung Cancer 1Recurrent Metastatic Non-Squamous Non Small Cell Lung Cancer 1Rectal Neoplasms 1Primary Myelofibrosis 1

Interventions

Oxaliplatin 14Cetuximab 11Leucovorin 9Fluorouracil 9Magnetic Resonance Spectroscopy 8Nivolumab 7pembrolizumab 6Capecitabine 6encorafenib 5Irinotecan 5Bevacizumab 5dehydroftorafur 4Specimen Handling 4adagrasib 3Immunoglobulin G 3Disulfides 3Biopsy 3selpercatinib 2durvalumab 2cemiplimab 2X-Rays 2Watchful Waiting 2Standard of Care 2Radiotherapy 2Panitumumab 2Observation 2Ipilimumab 2Injections 2Gemcitabine 2Folfox protocol 2

Date Range

30 days90 days1 yearAll

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Clinical Trials

1 trials
RecentStart dateEnrollment
Active not recruiting × Colonic Neoplasms × Pemetrexed × Clear all
NCT06607185 2026-05-26

A Study of the Pan-KRAS Inhibitor LY4066434 in Participants With KRAS Mutant Solid Tumors

Eli Lilly and Company

Phase 1 Active not recruiting
750 enrolled
GastrointestinalGynecologicThoracic

Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Esophageal Neoplasms, Lung Neoplasms, Neoplasm Metastasis, Ovarian Neoplasms, Pancreatic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms, Cholangiocarcinoma

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