Announcements Trials
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Phase

Phase 2 4Phase NA 1

Status

Completed 3Withdrawn 2

Sponsor Class

OTHER 3NIH 1INDUSTRY 1

Study Type

Interventional 5Observational 1

Sponsor

Cancer Type

Gastrointestinal 5

Conditions

Colorectal Neoplasms 23Neoplasm Metastasis 14Neoplasms 13Rectal Neoplasms 8Colorectal Cancer Metastatic 6Ovarian Neoplasms 5Lymphoma, Non-Hodgkin 5Colonic Neoplasms 5Uveal Melanoma 4Sarcoma 4Precursor Cell Lymphoblastic Leukemia-Lymphoma 4Melanoma 4Lymphoma, Mantle-Cell 4Lymphoma, Large-Cell, Immunoblastic 4Lymphoma, Large B-Cell, Diffuse 4Lymphoma, Follicular 4Lymphoma, B-Cell, Marginal Zone 4Leukemia, Lymphocytic, Chronic, B-Cell 4Fallopian Tube Neoplasms 4Carcinoma, Ovarian Epithelial 4Burkitt Lymphoma 4Uterine Cervical Neoplasms 3Urinary Bladder Neoplasms 3Urethral Neoplasms 3Stomach Neoplasms 3Prostatic Neoplasms 3Lung Neoplasms 3Glioblastoma 3Endometrial Neoplasms 3Carcinoma, Renal Cell 3

Interventions

Fluorouracil 218Leucovorin 201Oxaliplatin 191Irinotecan 148Bevacizumab 107Capecitabine 93Cetuximab 89Folfox protocol 54Chemotherapy, Adjuvant 34Panitumumab 30pembrolizumab 23Nivolumab 22Colonoscopy 22Gemcitabine 20Magnetic Resonance Spectroscopy 19Floxuridine 19IFL protocol 18Celecoxib 18Radiotherapy 17Neoadjuvant Therapy 17Early Intervention, Educational 17Drug Therapy 17Laparoscopy 14Cyclophosphamide 14Counseling 14trifluridine tipiracil drug combination 13regorafenib 13XELOX 13Exercise 13Erlotinib Hydrochloride 13

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
Interventional × Colonic Neoplasms × aflibercept × Clear all
NCT01652196 2025-02-05

Aflibercept and FOLFOX6 Treatment for Previously Untreated Stage IV Colorectal Cancer

Ohio State University Comprehensive Cancer Center

Phase 2 Completed
56 enrolled 14 charts
Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00407654 2024-03-04

VEGF Trap in Treating Patients With Previously Treated Metastatic Colorectal Cancer

National Cancer Institute (NCI)

Phase 2 Completed
75 enrolled 15 charts
Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms

NCT00851084 2016-06-07

AFFIRM

Sanofi

Phase 2 Completed
268 enrolled 16 charts
Gastrointestinal

Colonic Neoplasms, Neoplasm Metastasis, Rectal Neoplasms, Colorectal Neoplasms

NCT02235324 2015-05-06

Ziv-Aflibercept Followed by Ziv-Aflibercept, Fluorouracil, and Leucovorin Calcium in Treating Patients With Stage IV Colorectal Cancer

University of Southern California

Phase 2 Withdrawn
Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms

NCT01941173 2014-07-21

Short-Infusion Ziv-aflibercept in Treating Patients With Metastatic Colorectal Cancer Receiving Combination Chemotherapy

City of Hope Medical Center

Phase NA Withdrawn
Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms

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