Clinical Trials Browser

Phase 2 × OTHER × Colonic Neoplasms × Clear all

NCT07595874 2026-05-27

NEST3

Phase 2 Not yet recruiting

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms

NCT06890624 2026-05-22

OPTICAL-3

Phase 2 Not yet recruiting

Gastrointestinal

Colonic Neoplasms

NCT06580574 2026-05-15

Immune Checkpoint Inhibitors for Organ Preservation in Non-metastatic dMMR/MSI-H Gastric or Colon Cancers

Phase 2 Recruiting

Gastrointestinal

Colonic Neoplasms, Stomach Neoplasms

NCT07224022 2026-05-06

NACho

Phase 2 Not yet recruiting

Gastrointestinal

Colonic Neoplasms

NCT05961709 2026-05-04

The Phoenix Trial: Phase II Trial of Cemiplimab for the Non-operative Management of Localized dMMR Colon Cancer

Phase 2 Active not recruiting

Gastrointestinal

Colonic Neoplasms

NCT06778382 2026-04-28

Delayed Systemic Therapy Following Destructive Local Treatment of Pulmonary Oligometastases After No Evidence of Disease (NED) in Colorectal Cancer.

Phase 2 Recruiting

Gastrointestinal

Colonic Neoplasms

NCT07549906 2026-04-24

Neoadjuvant Iparomlimab/Tuvonralimab Plus CAPEOX Versus Iparomlimab/Tuvonralimab Plus CAPEOX and Propranolol for Locally Advanced pMMR Colon Cancer: A Prospective, Single-Center, Multi-Cohort Study

Phase 2 Not yet recruiting

Gastrointestinal

Colonic Neoplasms

NCT05197322 2026-04-17

NEOPRISM-CRC

Phase 2 Recruiting

Gastrointestinal

Colonic Neoplasms

NCT07405476 2026-04-17

Zanidatamab Before Surgery for the Treatment of HER2 Positive Colon and Rectal Cancer in Patients Planned for Curative Intent Treatment

Phase 2 Recruiting

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT07223424 2026-04-16

PSI-Immune

Phase 2 Recruiting

DermatologicGastrointestinalGenitourinaryGynecologicThoracic

Adenocarcinoma Of Esophagus, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Squamous Cell, Uterine Cervical Neoplasms, Colitis, Ulcerative, Colonic Neoplasms, Esophageal Neoplasms, Carcinoma, Hepatocellular, Melanoma

NCT07515963 2026-04-07

FULIRI Plus Targeted Therapy for First-line Conversion Therapy of Colorectal Cancer Liver Metastases.

Phase 2 Not yet recruiting

Gastrointestinal

Colonic Neoplasms, Colorectal Neoplasms

NCT07510932 2026-04-06

FIRST-K

Phase 2 Not yet recruiting

Gastrointestinal

Colonic Neoplasms

NCT04963283 2026-03-31

Study of Cabozantinib and Nivolumab in Refractory Metastatic Microsatellite Stable (MSS) Colorectal Cancer

Phase 2 Active not recruiting

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT05806931 2026-03-18

SCOTI

Phase 2 Recruiting

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms

NCT07011576 2026-03-18

FRUITFUL

Phase 2 Recruiting

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT07468630 2026-03-12

TRIUNITE-08

Phase 2 Recruiting

Gastrointestinal

Colonic Neoplasms

NCT03446157 2026-03-10

Palbociclib and Cetuximab in Metastatic Colorectal Cancer

Phase 2 Completed

24 enrolled 14 charts

Gastrointestinal

Colonic Neoplasms

NCT07432399 2026-03-06

PILDI

Phase 2 Recruiting

Gastrointestinal

Colonic Neoplasms, Colorectal Neoplasms

NCT03026140 2026-03-05

NICHE

Phase 2 Recruiting

Gastrointestinal

Colonic Neoplasms

NCT05672108 2026-03-05

Phase II Trial of Lung Chemoemobolization

Phase 2 Recruiting

GastrointestinalSarcomaThoracic

Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Mediastinal Neoplasms, Pleural Neoplasms, Sarcoma

NCT07409844 2026-02-20

RESET C2

Phase 2 Not yet recruiting

Gastrointestinal

Colonic Neoplasms

NCT07407465 2026-02-17

CHIMERA

Phase 2 Recruiting

Gastrointestinal

Colonic Neoplasms, Neoplasm Metastasis, Rectal Neoplasms, Colorectal Neoplasms

NCT06830239 2026-02-12

Superhero

Phase 2 Recruiting

Gastrointestinal

Colonic Neoplasms

NCT04109924 2026-02-10

TAS-102, Irinotecan, and Bevacizumab for the Treatment of Pre-treated Metastatic or Unresectable Colorectal Cancer, the TABAsCO Study

Phase 2 Completed

42 enrolled 12 charts

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00556413 2026-02-05

Cetuximab and Combination Chemotherapy as First-Line Therapy in Treating Patients With Metastatic Colorectal Cancer

Phase 2 Completed

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT06923787 2026-02-05

PILDI

Phase 2 Recruiting

Gastrointestinal

Colonic Neoplasms

NCT05062889 2026-02-03

ERASE-CRC

Phase 2 Suspended

Gastrointestinal

Colonic Neoplasms

NCT04505553 2026-01-21

Oral Cryotherapy Plus Acupressure and Acupuncture Versus Oral Cryotherapy for Decreasing Chemotherapy-Induced Peripheral Neuropathy From Oxaliplatin-Based Chemotherapy in Patients With Gastrointestinal Cancer

Phase 2 Completed

78 enrolled 14 charts

EndocrineGastrointestinalNET

Gastro-enteropancreatic neuroendocrine tumor, Anus Neoplasms, Appendiceal Neoplasms, Colonic Neoplasms, Esophageal Neoplasms, Gastrointestinal Neoplasms, Carcinoma, Hepatocellular, Adenoma, Islet Cell, Pancreatic Neoplasms, Rectal Neoplasms, Stomach Neoplasms

NCT00826540 2026-01-20

Sorafenib and Bevacizumab in Treating Patients With Metastatic Colorectal Cancer

Phase 2 Completed

83 enrolled 10 charts

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms

NCT05296681 2026-01-06

Microbiotic Product to Promote Microbiome Health and Improve Chemotherapy Delivery

Phase 2 Recruiting

Gastrointestinal

Colonic Neoplasms

NCT07279077 2025-12-26

MODIFI-L

Phase 2 Recruiting

Gastrointestinal

Colonic Neoplasms

NCT06731894 2025-12-05

Phytocannabinoids for Reducing Chronic Chemotherapy-Induced Peripheral Neuropathy in Breast and Colon Cancer Survivors

Phase 2 Recruiting

BreastGastrointestinal

Breast Neoplasms, Colonic Neoplasms

NCT06714292 2025-11-19

FLARECLIP

Phase 2 Active not recruiting

Gastrointestinal

Colonic Neoplasms

NCT05510895 2025-10-01

NeoBRAF

Phase 2 Completed

Gastrointestinal

Colonic Neoplasms, Colorectal Neoplasms

NCT07140679 2025-09-25

Immunotherapy (Toripalimab) for Reducing Recurrence Risk After Surgery for Mismatch Repair Deficient Stage IIB, IIC, or III Colon Cancer

Phase 2 Recruiting

Gastrointestinal

Colonic Neoplasms

NCT06124378 2025-09-24

Neoadjuvant Tislelizumab With Chemotherapy for the Treatment of MSS Colon Cancer

Phase 2 Active not recruiting

Gastrointestinal

Colonic Neoplasms

NCT06368141 2025-09-24

NeoCHIC

Phase 2 Recruiting

Gastrointestinal

Colonic Neoplasms

NCT07178717 2025-09-17

REFISH

Phase 2 Not yet recruiting

Gastrointestinal

Colonic Neoplasms

NCT05678257 2025-09-12

A Study of NUC-3373 in Combination With Other Agents in Patients With Colorectal Cancer

Phase 2 Terminated

180 enrolled 16 charts

Gastrointestinal

Colonic Neoplasms, Neoplasm Metastasis, Neoplasms, Colorectal Neoplasms

NCT02978612 2025-09-05

ACE

Phase 2 Completed

Gastrointestinal

Colonic Neoplasms, Colorectal Neoplasms

NCT07156682 2025-09-05

QL1706 Plus XELOX as Neoadjuvant Therapy for MSS/pMMR Clinical Stage III Colon Cancer

Phase 2 Not yet recruiting

Gastrointestinal

Colonic Neoplasms

NCT00766142 2025-08-29

COCHISE

Phase 2 Terminated

18 enrolled 9 charts

GastrointestinalGynecologic

Colonic Neoplasms, Peritoneal Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00492999 2025-08-17

Hepatic Arterial Infusion With Floxuridine and Dexamethasone Combined With Combination Chemotherapy in Treating Patients With Colorectal Cancer That Has Spread to the Liver

Phase 2 Active not recruiting

Gastrointestinal

Colonic Neoplasms, Neoplasm Metastasis, Rectal Neoplasms, Colorectal Neoplasms

NCT03482362 2025-08-03

EORTC1616

Phase 2 Completed

Gastrointestinal

Colonic Neoplasms

NCT07085169 2025-07-25

Low-dose Trifluridine/Tipiracil With Bevacizumab in mCRC

Phase 2 Recruiting

Gastrointestinal

Colonic Neoplasms

NCT03350126 2025-07-23

NIPICOL

Phase 2 Active not recruiting

Gastrointestinal

Colonic Neoplasms, Microsatellite Instability

NCT03442569 2025-07-01

PhII Trial Panitumumab, Nivolumab, Ipilimumab in Kras/Nras/BRAF Wild-type MSS Refractory mCRC

Phase 2 Completed

56 enrolled 13 charts

Gastrointestinal

Colonic Neoplasms

NCT06949111 2025-07-01

Radiotherapy + Systemic Therapy as Conversion Therapy for pMMR/MSS T4M0 Colon Cancer（Neo-Color）

Phase 2 Recruiting

Gastrointestinal

Colonic Neoplasms

NCT02368886 2025-06-18

Lower or Standard Dose Regorafenib in Treating Patients With Refractory Metastatic Colorectal Cancer

Phase 2 Completed

123 enrolled 21 charts

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT04625803 2025-06-17

Neoadjuvant Therapy for Locally Advanced Colon Cancer

Phase 2 Completed

64 enrolled 11 charts

Gastrointestinal

Colonic Neoplasms