Clinical Trials

GastrointestinalGynecologic

17 enrolled

Colonic Neoplasms, Rectal Neoplasms, Endometrial Neoplasms, Microsatellite Instability

NCT05983367 2026-02-20

A Study to Investigate Ompenaclid Combined With FOLFIRI Plus Bevacizumab in Advanced/Metastatic Colorectal Cancer

76 enrolled 19 charts

Colonic Neoplasms, Colorectal Neoplasms

NCT05578092 2026-02-19

A Phase 1 Study of MRTX0902 in Solid Tumors With Mutations in the KRAS MAPK Pathway

64 enrolled

GastrointestinalThoracic

Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Colorectal Neoplasms

NCT06457997 2026-01-29

A Study of PHN-010 in Patients With Advanced Solid Tumors

GastrointestinalGynecologicThoracic

26 enrolled

Carcinoma, Uterine Cervical Neoplasms, Colonic Neoplasms, Lung Neoplasms, Neoplasms, Ovarian Neoplasms, Endometrial Neoplasms

NCT04294160 2025-12-24

A Study of Select Drug Combinations in Adult Patients With Advanced/Metastatic BRAF V600 Colorectal Cancer

122 enrolled

Colonic Neoplasms, Neoplasm Metastasis, Rectal Neoplasms, Colorectal Neoplasms

NCT04844073 2025-12-04

A Study of TAK-186 (Also Known as MVC-101) in Adults With Advanced or Metastatic Cancer

GastrointestinalHead & NeckThoracic

95 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Head and Neck Neoplasms, Lung Neoplasms, Neoplasm Metastasis, Colorectal Neoplasms

NCT05169437 2025-10-29

PAVO

BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

22 enrolled 17 charts

Breast Neoplasms, Colonic Neoplasms, Esophageal Neoplasms, Head and Neck Neoplasms, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Pancreatic Neoplasms, Urologic Neoplasms, Endometrial Neoplasms

NCT02784795 2025-08-21

A Study of LY3039478 in Participants With Advanced or Metastatic Solid Tumors

BreastGastrointestinalSarcoma

94 enrolled 28 charts

Breast Neoplasms, Colonic Neoplasms, Sarcoma, Cholangiocarcinoma

NCT05124743 2025-07-30

HLA Typing & Tumor Neoantigen Identification for Phase I/II Study of Autologous TCR-T Cells in Subjects With Solid Tumors

Terminated

19 enrolled

GastrointestinalGynecologicThoracic

Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Endometrial Neoplasms, Cholangiocarcinoma

NCT04209465 2025-04-17

MasterKey-01

BreastGastrointestinalGenitourinaryGynecologicThoracic

91 enrolled 26 charts

Biliary Tract Neoplasms, Urinary Bladder Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Lung Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms

NCT05737706 2025-04-06

Study of MRTX1133 in Patients With Advanced Solid Tumors Harboring a KRAS G12D Mutation

63 enrolled

GastrointestinalThoracic

Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Pancreatic Neoplasms, Colorectal Neoplasms

NCT04975256 2024-12-16

Adagrasib in Combination With BI 1701963 in Patients With Cancer (KRYSTAL 14)

7 enrolled

GastrointestinalThoracic

Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Lung Neoplasms, Neoplasm Metastasis, Neoplasms, Pancreatic Neoplasms

NCT03127098 2024-08-06

QUILT-3.040: ETBX-011 (Ad5 [E1-, E2b-]-CEA(6D)) Vaccine in Combination With ALT-803 (Super-agonist IL-15) in Subjects Having CEA-Expressing Cancer

BreastGastrointestinalGynecologicHead & NeckThoracic

3 enrolled 6 charts

Breast Neoplasms, Colonic Neoplasms, Lung Neoplasms, Neoplasm Metastasis, Ovarian Neoplasms, Pancreatic Neoplasms, Thyroid Neoplasms

NCT04408599 2024-07-25

A Safety and Tolerability Study of NC410 in Subjects With Advanced or Metastatic Solid Tumors

GastrointestinalGynecologic

46 enrolled 21 charts

Colonic Neoplasms, Neoplasm Metastasis, Ovarian Neoplasms, Stomach Neoplasms

NCT03621982 2024-06-13

Study of ADCT-301 in Patients With Selected Advanced Solid Tumors

BreastDermatologicGastrointestinalGenitourinaryGynecologicThoracic

78 enrolled 39 charts

Urinary Bladder Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Colonic Neoplasms, Esophageal Neoplasms, Fallopian Tube Neoplasms, Melanoma, Ovarian Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms, Triple Negative Breast Neoplasms

NCT05121948 2024-03-08

A Study of HC-7366 to Establish the Maximum Tolerated Dose (MTD) and Recommended Phase 2 Dose (RP2D)

GastrointestinalGenitourinaryHead & NeckThoracic

35 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Colonic Neoplasms

NCT01605318 2024-01-24

Study of Labetuzumab Govitecan in Participants With Metastatic Colorectal Cancer

92 enrolled

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT04171700 2023-10-02

LODESTAR

BreastGastrointestinalGenitourinaryGynecologicSarcomaThoracic

83 enrolled 16 charts

Urinary Bladder Neoplasms, Breast Neoplasms, Carcinosarcoma, Uterine Cervical Neoplasms, Colonic Neoplasms, Esophageal Neoplasms, Fallopian Tube Neoplasms, Leiomyosarcoma, Lung Neoplasms, Neoplasm Metastasis, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Sarcoma, Stomach Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms

NCT01347645 2023-06-22

Irinotecan Plus E7820 Versus FOLFIRI in Second-Line Therapy in Patients With Locally Advanced or Metastatic Colon or Rectal Cancer

82 enrolled 14 charts

Colonic Neoplasms, Rectal Neoplasms

NCT01464593 2022-10-13

ABLATE

2 enrolled 5 charts

Colonic Neoplasms, Liver Neoplasms

NCT04555135 2022-04-01

ColonCADe

Phase NA Terminated

769 enrolled

Colonic Neoplasms, Colonic Polyps

NCT02628535 2022-02-08

Safety Study of MGD009 in B7-H3-expressing Tumors

BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckOther solid neoplasmSarcomaThoracic

67 enrolled

Squamous Cell Carcinoma of Head and Neck, Urinary Bladder Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Colonic Neoplasms, Melanoma, Mesothelioma, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Sarcoma, Thyroid Neoplasms

NCT01505166 2021-11-01

FANG-CLM

3 enrolled 9 charts

Colonic Neoplasms, Colorectal Neoplasms

NCT00041691 2021-08-19

Safety Study of 90Y-hMN14 to Treat Colorectal Cancer Patients With Limited Residual Disease After Surgery

30 enrolled

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT03449030 2021-03-22

A Study of TAK-164 in Participants With Advanced Gastrointestinal (GI) Cancer Expressing Guanylyl Cyclase C (GCC)

31 enrolled 28 charts

Colonic Neoplasms, Gastrointestinal Neoplasms

NCT03404934 2020-04-30

Clinical Study Verifying C-REX LapAid in Clinical Practice

Phase NA Terminated

13 enrolled

Colonic Neoplasms, Colorectal Neoplasms

NCT02425683 2020-02-10

Study of Colorectal Cancer Patients (Stage IIIC) With Either Regorafenib or Standard of Care (No Treatment) After Adjuvant FOLFOX

24 enrolled

BreastGastrointestinalThoracic

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT02883790 2019-02-22

Effects of Somnage® in the Management on Sleep and Mood in Cancer Patients

Phase NA Terminated

3 enrolled

Breast Neoplasms, Colonic Neoplasms, Lung Neoplasms

NCT01925274 2019-01-08

A Study Of PF-05212384 Plus Irinotecan Vs Cetuximab Plus Irinotecan In Patients With KRAS And NRAS Wild Type Metastatic Colorectal Cancer

19 enrolled 32 charts

Colonic Neoplasms, Colorectal Neoplasms

NCT00816777 2018-09-07

PARAGON

4 enrolled 5 charts

BreastDermatologicGastrointestinalGenitourinaryThoracic

Carcinoma, Colonic Neoplasms, Gastrointestinal Neoplasms, Neoplasm Metastasis, Neoplasms, Rectal Neoplasms, Stomach Neoplasms, Colorectal Neoplasms

NCT03073473 2018-07-20

Evaluation of the NantHealth GPS Cancer Test in Patients With Advanced Cancers

Terminated

40 enrolled

Breast Neoplasms, Colonic Neoplasms, Lung Neoplasms, Melanoma, Pancreatic Neoplasms, Prostatic Neoplasms

NCT00845039 2018-07-02

FC-4

4 enrolled 9 charts

DermatologicGastrointestinalSarcoma

Colonic Neoplasms, Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT02113683 2018-06-21

MMS-TM

Terminated

100 enrolled

Colonic Neoplasms, Melanoma, Sarcoma, Stomach Neoplasms

NCT02119676 2018-02-13

Study of Ruxolitinib in Colorectal Cancer Patients

396 enrolled 15 charts

Adenocarcinoma, Colonic Neoplasms, Colorectal Neoplasms

NCT01302405 2017-08-17

Safety and Efficacy Study of PRI-724 in Subjects With Advanced Solid Tumors

23 enrolled

Colonic Neoplasms, Neoplasm Metastasis, Neoplasms, Pancreatic Neoplasms

NCT02102412 2017-08-01

First in Man Aer-O-Scope

101 enrolled

Colonic Neoplasms

NCT01832857 2016-12-29

Phase 2 Safety, Tolerability and Efficacy Study of CPI-613 in Cancer Patients

BreastGastrointestinalThoracic

7 enrolled

Breast Neoplasms, Colonic Neoplasms, Esophageal Neoplasms, Carcinoma, Hepatocellular, Lung Neoplasms, Neoplasm Metastasis, Neoplasms, Stomach Neoplasms

NCT02002689 2016-05-02

SIGNATURE

DermatologicGastrointestinalGynecologicOther hematologic neoplasm

10 enrolled 9 charts

Basal Cell Nevus Syndrome, Colonic Neoplasms, Endometrial Neoplasms, Hematologic Neoplasms

NCT00689065 2013-11-01

Safety Study of CALAA-01 to Treat Solid Tumor Cancers

BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

24 enrolled

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Colonic Neoplasms, Lung Neoplasms, Melanoma, Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Skin Neoplasms, Thyroid Neoplasms, Endometrial Neoplasms

NCT01344902 2013-10-23

An Open Dose-finding Study of Oral Applied Hexaminolevulinate (HAL) Imaging in Patients With Suspicion or High Risk of Neoplasia in the Colon

13 enrolled

Colonic Neoplasms

NCT00147550 2013-09-13

MEK Inhibitor PD-325901 To Treat Advanced Breast Cancer, Colon Cancer, And Melanoma.

BreastDermatologicGastrointestinal

79 enrolled

Breast Neoplasms, Colonic Neoplasms, Melanoma

NCT01329809 2013-04-10

Neoadjuvant Study of Recombinant Vaccinia Virus to Treat Metastatic Colorectal Carcinoma in Patients Undergoing Complete Resection of Liver Tumors

2 enrolled

GastrointestinalGenitourinaryThoracic

Colonic Neoplasms, Colorectal Neoplasms

NCT00332280 2013-03-20

Study to Evaluate the Clinical Benefit Response in Cancer Patients With Advanced Disease With AMT2003 Versus Placebo

Phase 2/3 Terminated

67 enrolled

Colonic Neoplasms, Esophageal Neoplasms, Gallbladder Neoplasms, Gastrointestinal Neoplasms, Genital Neoplasms, Female, Liver Neoplasms, Lung Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Stomach Neoplasms

NCT00006269 2012-05-25

Octreotide in the Prevention of Diarrhea in Patients Receiving Irinotecan for Metastatic Colon Cancer

Phase 3 Terminated

89 enrolled

Colonic Neoplasms, Diarrhea, Rectal Neoplasms, Colorectal Neoplasms

NCT00277303 2010-02-22

Study of XL999 in Patients With Metastatic Colorectal Cancer

17 enrolled

Colonic Neoplasms, Colorectal Neoplasms

NCT00249301 2008-04-01

A Study of MLN8054 in Patients With Advanced Solid Tumors