Clinical Trials Browser

Active not recruiting × Colorectal Neoplasms, Hereditary Nonpolyposis × 1 year × Clear all

NCT02912559 2026-06-01

Combination Chemotherapy With or Without Atezolizumab in Treating Patients With Stage III Colon Cancer and Deficient DNA Mismatch Repair

Phase 3 Active not recruiting

712 enrolled 14 charts

Gastrointestinal

Colonic Neoplasms, Colorectal Neoplasms, Hereditary Nonpolyposis, DNA Repair-Deficiency Disorders

NCT05419011 2026-05-27

Testing a Combination of Vaccines for Cancer Prevention in Lynch Syndrome

Phase 2 Active not recruiting

Gastrointestinal

Colorectal Neoplasms, Hereditary Nonpolyposis, Colorectal Neoplasms

NCT02359565 2026-05-13

Pembrolizumab in Treating Younger Patients With Recurrent, Progressive, or Refractory High-Grade Gliomas, Diffuse Intrinsic Pontine Gliomas, Hypermutated Brain Tumors, Ependymoma or Medulloblastoma

Phase 1 Active not recruiting

CNSGastrointestinal

Familial ependymoma, Turcot syndrome, Diffuse Intrinsic Pontine Glioma, Brain Neoplasms, Colorectal Neoplasms, Hereditary Nonpolyposis, Ependymoma, Glioma, Medulloblastoma

NCT04125914 2026-04-16

Weight Management and Health Behavior Intervention in Lowering Cancer Risk for BRCA Positive and Lynch Syndrome Families

Phase NA Active not recruiting

BreastGastrointestinal

Breast Cancer, Familial, Colorectal Neoplasms, Hereditary Nonpolyposis

NCT05692596 2026-04-01

The Pancreas Interception Center (PIC) for Early Detection, Prevention, and Novel Therapeutics

Active not recruiting

Gastrointestinal

Ataxia Telangiectasia, Colorectal Neoplasms, Hereditary Nonpolyposis, Dysplastic Nevus Syndrome, Pancreatic Cyst, Peutz-Jeghers Syndrome, Pancreatitis, Chronic

NCT02194387 2026-03-09

Energy Balance Interventions in Increasing Physical Activity in Breast Cancer Gene Positive Patients, Lynch Syndrome-Positive Patients, CLL Survivors or High-Risk Family Members

Phase NA Active not recruiting

BreastGastrointestinalGynecologicLymphoidOther hematologic neoplasm

Breast Neoplasms, Colorectal Neoplasms, Hereditary Nonpolyposis, Fatigue, Ovarian Neoplasms, Leukemia, Lymphocytic, Chronic, B-Cell, Overweight

NCT05677048 2026-03-09

Feasibility Study: IGNITE-TX (Identifying Individuals for Genetic Testing & Treatment) Intervention

Phase NA Active not recruiting

BreastGastrointestinalGynecologic

Breast Neoplasms, Colonic Neoplasms, Colorectal Neoplasms, Hereditary Nonpolyposis, Ovarian Neoplasms, Pancreatic Neoplasms, Uterine Neoplasms, Endometrial Neoplasms, Hereditary Breast and Ovarian Cancer Syndrome

NCT05078866 2026-03-03

Cancer Preventive Vaccine Nous-209 for Lynch Syndrome Patients

Phase 1/2 Active not recruiting

Gastrointestinal

Colorectal Neoplasms, Hereditary Nonpolyposis, Colorectal Neoplasms

NCT02371135 2026-02-05

Metagenomic Evaluation of the Gut Microbiome in Patients With Lynch Syndrome and Other Hereditary Colonic Polyposis Syndromes

Active not recruiting

Gastrointestinal

Colorectal Neoplasms, Hereditary Nonpolyposis

NCT04261972 2026-01-14

CHARM1

Active not recruiting

BreastGastrointestinalGynecologic

Colorectal Neoplasms, Hereditary Nonpolyposis, Neoplasms, Neoplastic Syndromes, Hereditary, Hereditary Breast and Ovarian Cancer Syndrome

NCT00582296 2026-01-07

Multi-Organ Screening Recommendations in Patients With Lynch Syndrome

Active not recruiting

Gastrointestinal

Colorectal Neoplasms, Hereditary Nonpolyposis

NCT00261456 2025-09-26

The IMPACT Study - Identification of Men With a Genetic Predisposition to ProstAte Cancer

Active not recruiting

GastrointestinalGenitourinary

Colorectal Neoplasms, Hereditary Nonpolyposis, Prostatic Neoplasms, Genetic Predisposition to Disease

NCT02813824 2025-07-08

AAS-Lynch

Phase 3 Active not recruiting

Gastrointestinal

Colorectal Neoplasms, Hereditary Nonpolyposis