Clinical Trials

280 enrolled

Phase NA Active not recruiting

Digestive System Neoplasms, Gastrointestinal Neoplasms, Intestinal Neoplasms, Neoplasm Metastasis, Colorectal Neoplasms

NCT04832763 2026-06-05

Medical and Psychosocial Issues in Adolescents and Young Adults With Colorectal Cancer

32 enrolled

Colorectal Neoplasms

NCT05379595 2026-06-05

OrigAMI-1

225 enrolled

Colorectal Neoplasms

NCT06149481 2026-06-05

Phase I/II Study of the Combination Immunotherapy Regimen: SX-682, TriAdeno Vaccine, Retifanlimab and IL-15 Agonist N-803 (STAR15) for Metastatic Colorectal Cancer (mCRC)

60 enrolled

Colorectal Neoplasms

NCT06307548 2026-06-05

Fluorescence Image Guided Surgery Followed by Intraoperative Photodynamic Therapy for Improving Local Tumor Control in Patients With Locally Advanced or Recurrent Colorectal Cancer

21 enrolled

Colorectal Neoplasms

NCT06420726 2026-06-05

Resistance Exercise and Creatine in Colorectal Cancer

Phase NA Completed

27 enrolled

Colorectal Neoplasms

NCT06662786 2026-06-05

OrigAMI-2

1,000 enrolled

Colorectal Neoplasms

NCT06710756 2026-06-05

Lead-212 PSV359 Therapy for Patients With Solid Tumors

GastrointestinalGynecologicHead & NeckOther solid neoplasmSarcomaThoracic

112 enrolled

Esophageal Neoplasms, Head and Neck Neoplasms, Mesothelioma, Ovarian Neoplasms, Sarcoma, Stomach Neoplasms, Colorectal Neoplasms

NCT06750094 2026-06-05

OrigAMI-3

700 enrolled

Colorectal Neoplasms

NCT07071961 2026-06-05

Regorafenib (Reg) and Lorigerlimab (Lor), RELO Regimen, in Treatment of High-risk Patients With Colorectal Cancer With Radiographic Occult Molecular Residual Disease After End of Established Definitive Therapy [ReLOAD Trial]

Phase 2 Suspended

16 enrolled

Colorectal Neoplasms

NCT07107230 2026-06-05

A Study of JNJ-95437446 in Participants With Advanced-Stage Solid Tumors

380 enrolled

Colorectal Neoplasms

NCT07213609 2026-06-05

A Study to Investigate the Safety and Preliminary Efficacy of GSK5460025 Alone or in Combination With Other Anti-cancer Agents in Participants With Solid Tumors

GastrointestinalGynecologic

47 enrolled

Turcot syndrome, Colonic Neoplasms, Neoplasms, Rectal Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms

NCT07328516 2026-06-05

Natural History Study of Early Life Exposures in Agriculture (ELEA)

Enrolling by invitation

64,277 enrolled

BreastDermatologicGastrointestinalGenitourinaryOther hematologic neoplasm

Breast Neoplasms, Leukemia, Melanoma, Prostatic Neoplasms, Colorectal Neoplasms

NCT07618273 2026-06-05

Smart Symptom Tracking ALEX Application for Tracking and Monitoring Gastrointestinal Health, Smart Horizons Pilot Trial

50 enrolled

Phase EARLY_PHASE1 Not yet recruiting

Colorectal Neoplasms

NCT07627191 2026-06-05

GLP-1 RA Plus SOC Treatment in First-line, Metastatic Pancreatic, Colorectal, or Hepatocellular Cancer

30 enrolled

Gastrointestinal Neoplasms, Carcinoma, Hepatocellular, Pancreatic Neoplasms, Colorectal Neoplasms

NCT07628998 2026-06-05

Impact of SMS Messaging on Participation in Colorectal Cancer Screening.

10,084 enrolled

Patient Compliance, Patient Participation, Colorectal Neoplasms

NCT07629960 2026-06-05

A First-in-Human Trial of BLU-924 (SAR449336) in Advanced Solid Tumors Harboring KRAS Mutations

Phase 1 Not yet recruiting

265 enrolled

GastrointestinalThoracic

Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Lung Neoplasms, Neoplasm Metastasis, Pancreatic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT07630961 2026-06-05

Phase I Study of JFI447 [68Ga]Ga-DFC413 and Comparison to FFG233 [68Ga]Ga-NNS309 in Patients With Solid Tumors

66 enrolled

BreastGastrointestinalSarcomaThoracic

Carcinoma, Non-Small-Cell Lung, Sarcoma, Colorectal Neoplasms, Triple Negative Breast Neoplasms

NCT01719926 2026-06-04

PIFA

Phase 1 Completed

13 enrolled

GastrointestinalGynecologic

Esophageal Neoplasms, Ovarian Neoplasms, Colorectal Neoplasms

NCT02070146 2026-06-04

PLCRC

Recruiting

50,000 enrolled

DermatologicGastrointestinalGenitourinaryGynecologicThoracic

Colorectal Neoplasms

NCT04458259 2026-06-04

Study of PF-07265807 in Participants With Metastatic Solid Tumors.

Phase 1 Terminated

88 enrolled

Parkinson Disease 4, Autosomal Dominant Lewy Body, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Transitional Cell, Uterine Cervical Neoplasms, Esophageal Neoplasms, Carcinoma, Hepatocellular, Melanoma, Neoplasm Metastasis, Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Carcinoma, Merkel Cell, Endometrial Neoplasms, Small Cell Lung Carcinoma

NCT04566393 2026-06-04

Expanded Access to Ulixertinib (BVD-523) in Patients With Advanced MAPK Pathway-Altered Malignancies

Available

CNSDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

Urinary Bladder Neoplasms, Carcinoma, Non-Small-Cell Lung, Esophageal Neoplasms, Glioblastoma, Head and Neck Neoplasms, Carcinoma, Hepatocellular, Melanoma, Ovarian Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms, Thyroid Neoplasms, Colorectal Neoplasms, Cholangiocarcinoma

NCT04800822 2026-06-04

PF-07284892 in Participants With Advanced Solid Tumors

Phase 1 Terminated

53 enrolled

CNSGastrointestinalThoracic

Carcinoma, Non-Small-Cell Lung, Neurofibromatosis 1, Hereditary Sensory and Autonomic Neuropathies, Colorectal Neoplasms

NCT05253651 2026-06-04

MOUNTAINEER-03

400 enrolled

Phase 2 Active not recruiting

Colorectal Neoplasms

NCT05576896 2026-06-04

Hydroxychloroquine in Combination With Encorafenib and Cetuximab or Panitumumab in the Treatment of Metastatic BRAF-mutated Colorectal Cancer Refractory

7 enrolled

Colorectal Neoplasms

NCT06314022 2026-06-04

PREPCOLON

470 enrolled

Colorectal Neoplasms

NCT06756035 2026-06-04

CT-95 in Advanced Cancers Associated With Mesothelin Expression

GastrointestinalGynecologicOther solid neoplasmThoracic

70 enrolled

Carcinoma, Ovarian Epithelial, Mesothelioma, Malignant, Neoplasm Metastasis, Neoplasms, Colorectal Neoplasms

NCT06760819 2026-06-04

panSOHO

Phase 2 Recruiting

111 enrolled

BreastGastrointestinalGenitourinaryGynecologicSarcoma

Biliary Tract Neoplasms, Urinary Bladder Neoplasms, Breast Neoplasms, Uterine Cervical Neoplasms, Esophageal Neoplasms, Gallbladder Neoplasms, Gastrointestinal Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Sarcoma, Stomach Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms, Gastrointestinal Stromal Tumors

NCT06822530 2026-06-04

A Multilevel Intervention to Increase Colorectal Cancer Screening Tests in Patients With Abnormal Fecal Immunochemical Test Results, PROACT Trial

Phase NA Enrolling by invitation

682 enrolled

Colorectal Neoplasms

NCT06922383 2026-06-04

A Clinical Study of Arfolitixorin in Patients With mCRC

90 enrolled

Colorectal Neoplasms

NCT07066657 2026-06-04

A Study of MRG007 (ARR-217) in Patients With Advanced Solid Tumors

405 enrolled

Pancreatic Neoplasms, Stomach Neoplasms, Colorectal Neoplasms

NCT07162337 2026-06-04

BILMOD

40 enrolled

GastrointestinalOther

Obesity, Colorectal Neoplasms

NCT07213791 2026-06-04

FiREBOLT

BreastGastrointestinalGynecologic

241 enrolled

Pancreatic Intraductal Neoplasms, Breast Neoplasms, Esophageal Neoplasms, Ovarian Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Cholangiocarcinoma

NCT07222800 2026-06-04

Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer

800 enrolled

Colonic Diseases, Colonic Neoplasms, Digestive System Diseases, Digestive System Neoplasms, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Intestinal Diseases, Intestinal Neoplasms, Neoplasm Metastasis, Neoplasms by Site, Rectal Diseases, Colorectal Neoplasms

NCT07225309 2026-06-04

A Study of Meaning-Centered Therapy for Mexican Adults With Advanced Cancer

BreastGastrointestinalGenitourinaryHead & Neck

300 enrolled

Breast Neoplasms, Prostatic Neoplasms, Thyroid Neoplasms, Colorectal Neoplasms

NCT07403981 2026-06-04

Advocacy, Partnership, Outreach, and Yielding Optimized Care for Oncology Patients

60 enrolled

Colorectal Neoplasms

NCT07569250 2026-06-04

CoSMMO

7,220 enrolled

Colorectal Neoplasms

NCT07611071 2026-06-04

AI-Integrated Emotional Granularity Training for Resilience and Quality of Life in Colorectal Cancer Survivors

54 enrolled

Emotional Regulation, Colorectal Neoplasms

NCT07612436 2026-06-04

AI-empowered Nudge to Improve Colonoscopy Uptake (AINC)

1,680 enrolled

Colorectal Neoplasms

NCT07619859 2026-06-04

Impact of Fusobacterium Nucleatum on Response to Anti-EGFR Therapy in Metastatic Colorectal Cancer

Active not recruiting

500 enrolled

Phase 2 Active not recruiting

Colorectal Neoplasms

NCT00492999 2026-06-03

Hepatic Arterial Infusion With Floxuridine and Dexamethasone Combined With Combination Chemotherapy in Treating Patients With Colorectal Cancer That Has Spread to the Liver

64 enrolled

Phase 2 Active not recruiting

Colonic Neoplasms, Neoplasm Metastasis, Rectal Neoplasms, Colorectal Neoplasms

NCT02465060 2026-06-03

Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial)

6,452 enrolled 1 FDA

BreastCNSDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckLymphoidOther hematologic neoplasmPlasma cellThoracic

Urinary Bladder Neoplasms, Breast Neoplasms, Carcinoma, Renal Cell, Uterine Cervical Neoplasms, Colonic Neoplasms, Esophageal Neoplasms, Glioma, Carcinoma, Hepatocellular, Lung Neoplasms, Lymphoma, Melanoma, Multiple Myeloma, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Rectal Neoplasms, Stomach Neoplasms, Thyroid Neoplasms, Uterine Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms, Hematologic Neoplasms

NCT02997228 2026-06-03

Testing the Addition of Atezolizumab to Combination Chemotherapy or Atezolizumab Alone for Metastatic Colon or Rectal Cancer, the COMMIT Study

Phase 3 Active not recruiting

120 enrolled

Phase NA Active not recruiting

Colorectal Neoplasms

NCT04403022 2026-06-03

da Vinci SP® Investigational Device Exemption Study in Colorectal Procedures

60 enrolled 9 charts

Colonic Neoplasms, Colorectal Neoplasms

NCT05319314 2026-06-03

CARABiNER

155 enrolled

Colorectal Neoplasms

NCT05546476 2026-06-03

PROACC-1

Phase 2 Completed

187 enrolled 24 charts

GastrointestinalThoracic

Anorexia, Cachexia, Carcinoma, Non-Small-Cell Lung, Fatigue, Neoplasms, Pancreatic Neoplasms, Colorectal Neoplasms, Weight Loss

NCT06040541 2026-06-03

Study of RMC-9805 in Participants With KRAS G12D-Mutant Solid Tumors