Clinical Trials

Colorectal Neoplasms

NCT06756035 2026-06-04

CT-95 in Advanced Cancers Associated With Mesothelin Expression

GastrointestinalGynecologicOther solid neoplasmThoracic

70 enrolled

Carcinoma, Ovarian Epithelial, Mesothelioma, Malignant, Neoplasm Metastasis, Neoplasms, Colorectal Neoplasms

NCT06760819 2026-06-04

panSOHO

BreastGastrointestinalGenitourinaryGynecologicSarcoma

111 enrolled

Biliary Tract Neoplasms, Urinary Bladder Neoplasms, Breast Neoplasms, Uterine Cervical Neoplasms, Esophageal Neoplasms, Gallbladder Neoplasms, Gastrointestinal Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Sarcoma, Stomach Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms, Gastrointestinal Stromal Tumors

NCT06922383 2026-06-04

A Clinical Study of Arfolitixorin in Patients With mCRC

Phase 1/2 Recruiting

90 enrolled

Colorectal Neoplasms

NCT07066657 2026-06-04

A Study of MRG007 (ARR-217) in Patients With Advanced Solid Tumors

405 enrolled

Pancreatic Neoplasms, Stomach Neoplasms, Colorectal Neoplasms

NCT07213791 2026-06-04

FiREBOLT

BreastGastrointestinalGynecologic

241 enrolled

Pancreatic Intraductal Neoplasms, Breast Neoplasms, Esophageal Neoplasms, Ovarian Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Cholangiocarcinoma

NCT07222800 2026-06-04

Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer

Phase 3 Recruiting

800 enrolled

Phase NA Active not recruiting

Colonic Diseases, Colonic Neoplasms, Digestive System Diseases, Digestive System Neoplasms, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Intestinal Diseases, Intestinal Neoplasms, Neoplasm Metastasis, Neoplasms by Site, Rectal Diseases, Colorectal Neoplasms

NCT04403022 2026-06-03

da Vinci SP® Investigational Device Exemption Study in Colorectal Procedures

60 enrolled 9 charts

Colonic Neoplasms, Colorectal Neoplasms

NCT05319314 2026-06-03

CARABiNER

Phase 1/2 Recruiting

155 enrolled

Colorectal Neoplasms

NCT05546476 2026-06-03

PROACC-1

Phase 2 Completed

187 enrolled 24 charts

Anorexia, Cachexia, Carcinoma, Non-Small-Cell Lung, Fatigue, Neoplasms, Pancreatic Neoplasms, Colorectal Neoplasms, Weight Loss

NCT06040541 2026-06-03

Study of RMC-9805 in Participants With KRAS G12D-Mutant Solid Tumors

604 enrolled

Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Gastrointestinal Neoplasms, Lung Neoplasms, Neoplasm Metastasis, Pancreatic Neoplasms, Colorectal Neoplasms

NCT06764771 2026-06-03

A Study of BMS-986488 as Monotherapy and Combination Therapy in Participants With Advanced Malignant Tumors

GastrointestinalGenitourinaryThoracic

437 enrolled

Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Neoplasms, Colorectal Neoplasms

NCT07114601 2026-06-03

OMNIRAY

BreastGastrointestinalGenitourinaryGynecologic

421 enrolled

Breast Neoplasms, Esophageal Neoplasms, Neoplasm Metastasis, Prostatic Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms

NCT07527832 2026-06-03

An Observational Study to Learn About the Medicine - BEVACIZUMAB BS [Pfizer] in Colorectal Cancer Patients From Japan.

Completed

1,000 enrolled

Hemorrhage, Colorectal Neoplasms

NCT07623174 2026-06-03

A Study of Fruquintinib in Adults With Metastatic Colorectal Cancer in Poland

Not yet recruiting

110 enrolled

Phase 1 Not yet recruiting

Colorectal Neoplasms

NCT07623369 2026-06-03

A First-in-Human Study of HH160 in Patients With Advanced Solid Tumors

56 enrolled

BreastGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Transitional Cell, Uterine Cervical Neoplasms, Carcinoma, Hepatocellular, Ovarian Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms, Small Cell Lung Carcinoma, Triple Negative Breast Neoplasms

NCT07623642 2026-06-03

A Phase II Study of GV20-0251 in Combination With Anti-PD-1 Monoclonal Antibodies in Patients With Unresectable, Locally Advanced, or Metastatic Solid Tumors.

Phase 2 Not yet recruiting

227 enrolled

BreastGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

Squamous Cell Carcinoma of Head and Neck, Esophageal Squamous Cell Carcinoma, Carcinoma, Non-Small-Cell Lung, Uterine Cervical Neoplasms, Gallbladder Neoplasms, Prostatic Neoplasms, Colorectal Neoplasms, Cholangiocarcinoma, Small Cell Lung Carcinoma, Triple Negative Breast Neoplasms

NCT07624214 2026-06-03

Study of LT-010391 in Participants With KRAS G12D-Mutant Solid Tumors

Phase 1 Not yet recruiting

198 enrolled

Phase 1/2 Active not recruiting

Carcinoma, Non-Small-Cell Lung, Colorectal Neoplasms

NCT04083599 2026-06-02

GEN1042 Safety Trial and Anti-tumor Activity in Participants With Malignant Solid Tumors

350 enrolled

DermatologicGastrointestinalHead & NeckThoracic

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Melanoma, Colorectal Neoplasms

NCT04449874 2026-06-02

A Study to Evaluate the Safety, Pharmacokinetics, and Activity of GDC-6036 Alone or in Combination in Participants With Advanced or Metastatic Solid Tumors With a KRAS G12C Mutation

Phase 1 Active not recruiting

498 enrolled

BreastGastrointestinalGenitourinaryGynecologicOther solid neoplasmThoracic

Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis, Colorectal Neoplasms

NCT04981119 2026-06-02

BASECAMP-1

Recruiting

200 enrolled

Mesothelioma, Malignant, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Kidney Neoplasms, Mesothelioma, Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Colorectal Neoplasms, Triple Negative Breast Neoplasms

NCT05787587 2026-06-02

A Study of PARG Inhibitor IDE161 in Participants With Advanced Solid Tumors

Phase 1 Active not recruiting

216 enrolled

BreastGastrointestinalGenitourinaryGynecologicHead & Neck

Mental Retardation, X-Linked, With Or Without Seizures, Arx-Related, Breast Neoplasms, Head and Neck Neoplasms, Ovarian Neoplasms, Prostatic Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms

NCT06820463 2026-06-02

AndroMETa-CRC

390 enrolled

Colorectal Neoplasms

NCT06917079 2026-06-02

BBO-11818 in Adult Subjects With KRAS Mutant Cancer

665 enrolled

Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis, Colorectal Neoplasms

NCT07023289 2026-06-02

A Study to Assess Adverse Events and Change in Disease Activity in Adult Participants Receiving Intravenously Infused Telisotuzumab Adizutecan Alone or With Standard of Care in Participants With Post Adjuvant Circulating Tumor DNA Positive Colorectal Cancer and No Radiographic Evidence of Disease

140 enrolled

Neoplasms, Colorectal Neoplasms

NCT07454642 2026-06-02

FOCUS-01

174 enrolled

Phase 3 Not yet recruiting

Colorectal Neoplasms, Small Cell Lung Carcinoma

NCT07620574 2026-06-02

Long-Term Extension Study for Participants Previously Enrolled in an Exelixis-Sponsored Study

5,000 enrolled

GastrointestinalGenitourinary

Carcinoma, Renal Cell, Carcinoma, Hepatocellular, Neoplasms, Prostatic Neoplasms, Colorectal Neoplasms

NCT05783622 2026-06-01

Study of JANX008 in Subjects With Advanced or Metastatic Solid Tumor Malignancies

Phase 1 Active not recruiting

130 enrolled

BreastGastrointestinalGenitourinaryHead & NeckThoracic

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Colorectal Neoplasms, Small Cell Lung Carcinoma, Triple Negative Breast Neoplasms

NCT06607458 2026-06-01

DEL-LIVER

90 enrolled

Rectal Neoplasms, Colorectal Neoplasms

NCT06808685 2026-06-01

Real World Multicenter National Study to Evaluate the Effectiveness and Safety of Biosimilar Bevacizumab Elovie

Recruiting

133 enrolled

Colorectal Neoplasms

NCT07284849 2026-06-01

A Study to Evaluate the Efficacy and Safety of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal Cancer

Phase 3 Recruiting

700 enrolled

Colonic Neoplasms, Colorectal Neoplasms

NCT07349537 2026-06-01

Study of RMC-5127 in Patients With Advanced KRAS G12V-Mutant Solid Tumors

574 enrolled

BreastDermatologicGastrointestinalGenitourinaryHead & NeckThoracic

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Pancreatic Neoplasms, Colorectal Neoplasms

NCT03289962 2026-05-29

A Study of Autogene Cevumeran (RO7198457) as a Single Agent and in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Tumors

Phase 1 Completed

273 enrolled

Urinary Bladder Neoplasms, Carcinoma, Non-Small-Cell Lung, Head and Neck Neoplasms, Kidney Neoplasms, Melanoma, Colorectal Neoplasms, Triple Negative Breast Neoplasms

NCT03693170 2026-05-29

ANCHOR-CRC

Phase 2 Completed

95 enrolled 30 charts

Phase 1/2 Active not recruiting

Colorectal Neoplasms

NCT04956640 2026-05-29

Study of LY3537982 in Cancer Patients With a Specific Genetic Mutation (KRAS G12C)

540 enrolled

GastrointestinalGynecologicThoracic

Biliary Tract Neoplasms, Carcinoma, Non-Small-Cell Lung, Ovarian Neoplasms, Pancreatic Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms

NCT06598007 2026-05-29

A Study to Determine the Effect of CT3001 in Patients With Advanced Solid Tumors

Phase 1/2 Recruiting

78 enrolled

Colorectal Neoplasms

NCT06848348 2026-05-29

Efficacy and Safety Study of Halneuron in the Treatment of Chemotherapy-Induced Neuropathic Pain

240 enrolled

BreastGastrointestinal

Cancer Pain, Breast Neoplasms, Neoplasms, Neuralgia, Pain, Peripheral Nervous System Diseases, Colorectal Neoplasms

NCT07321106 2026-05-29

A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Anti-tumor Activity of CBI-1214 T Cell Engager in Participants With Advanced or Metastatic MSS/MSI-L Colorectal Cancer

80 enrolled

Colonic Neoplasms, Neoplasms, Colorectal Neoplasms

NCT07544589 2026-05-29

A Phase 1 Study Evaluating DISP-10 in Participants With Advanced Gastrointestinal Cancers

66 enrolled