Clinical Trials Browser

Phase 1/2 × Colorectal Neoplasms × 30 days × Clear all

NCT05379595 2026-06-05

OrigAMI-1

Phase 1/2 Recruiting

Gastrointestinal

Colorectal Neoplasms

NCT06149481 2026-06-05

Phase I/II Study of the Combination Immunotherapy Regimen: SX-682, TriAdeno Vaccine, Retifanlimab and IL-15 Agonist N-803 (STAR15) for Metastatic Colorectal Cancer (mCRC)

Phase 1/2 Recruiting

Gastrointestinal

Colorectal Neoplasms

NCT06307548 2026-06-05

Fluorescence Image Guided Surgery Followed by Intraoperative Photodynamic Therapy for Improving Local Tumor Control in Patients With Locally Advanced or Recurrent Colorectal Cancer

Phase 1/2 Recruiting

Gastrointestinal

Colorectal Neoplasms

NCT06710756 2026-06-05

Lead-212 PSV359 Therapy for Patients With Solid Tumors

Phase 1/2 Recruiting

GastrointestinalGynecologicHead & NeckOther solid neoplasmSarcomaThoracic

Esophageal Neoplasms, Head and Neck Neoplasms, Mesothelioma, Ovarian Neoplasms, Sarcoma, Stomach Neoplasms, Colorectal Neoplasms

NCT07213609 2026-06-05

A Study to Investigate the Safety and Preliminary Efficacy of GSK5460025 Alone or in Combination With Other Anti-cancer Agents in Participants With Solid Tumors

Phase 1/2 Recruiting

GastrointestinalGynecologic

Turcot syndrome, Colonic Neoplasms, Neoplasms, Rectal Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms

NCT07629960 2026-06-05

A First-in-Human Trial of BLU-924 (SAR449336) in Advanced Solid Tumors Harboring KRAS Mutations

Phase 1/2 Recruiting

GastrointestinalThoracic

Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Lung Neoplasms, Neoplasm Metastasis, Pancreatic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT06922383 2026-06-04

A Clinical Study of Arfolitixorin in Patients With mCRC

Phase 1/2 Recruiting

Gastrointestinal

Colorectal Neoplasms

NCT05319314 2026-06-03

CARABiNER

Phase 1/2 Recruiting

Gastrointestinal

Colorectal Neoplasms

NCT04083599 2026-06-02

GEN1042 Safety Trial and Anti-tumor Activity in Participants With Malignant Solid Tumors

Phase 1/2 Active not recruiting

DermatologicGastrointestinalHead & NeckThoracic

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Melanoma, Colorectal Neoplasms

NCT04956640 2026-05-29

Study of LY3537982 in Cancer Patients With a Specific Genetic Mutation (KRAS G12C)

Phase 1/2 Active not recruiting

GastrointestinalGynecologicThoracic

Biliary Tract Neoplasms, Carcinoma, Non-Small-Cell Lung, Ovarian Neoplasms, Pancreatic Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms

NCT06598007 2026-05-29

A Study to Determine the Effect of CT3001 in Patients With Advanced Solid Tumors

Phase 1/2 Recruiting

Gastrointestinal

Colorectal Neoplasms

NCT00159484 2026-05-28

Phase I/II Study of Celebrex and EPO906 in Patients With Metastatic Colorectal Cancer

Phase 1/2 Completed

75 enrolled 25 charts

Gastrointestinal

Colonic Neoplasms, Colorectal Neoplasms

NCT05919264 2026-05-28

FOG-001 in Locally Advanced or Metastatic Solid Tumors

Phase 1/2 Recruiting

CNSGastrointestinalGenitourinaryGynecologicSarcoma

Craniopharyngioma, Carcinoma, Hepatocellular, Neoplasm Metastasis, Neoplasms, Adenomatous Polyposis Coli, Prostatic Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms, Desmoid Tumors

NCT07223047 2026-05-28

A Study to Evaluate the Safety, Tolerability, and Efficacy of BMS-986523 Alone and in Combination With Anti-Cancer Agents in Participants With Advanced Solid Malignancies

Phase 1/2 Recruiting

GastrointestinalThoracic

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Pancreatic Neoplasms, Colorectal Neoplasms

NCT06051695 2026-05-26

EVEREST-2

Phase 1/2 Recruiting

GastrointestinalGynecologicOther solid neoplasmThoracic

Mesothelioma, Malignant, Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Lung Neoplasms, Mesothelioma, Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Rectal Neoplasms, Recurrence, Colorectal Neoplasms

NCT06324357 2026-05-26

Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in Combination With Other Treatments to Test Whether it Helps People With Different Types of HER2+ Cancer That Has Spread

Phase 1/2 Recruiting

BreastGastrointestinal

Adenocarcinoma Of Esophagus, Breast Neoplasms, Colorectal Neoplasms

NCT04017650 2026-05-22

Encorafenib, Cetuximab, and Nivolumab in Treating Patients With Microsatellite Stable, BRAFV600E Mutated Unresectable or Metastatic Colorectal Cancer

Phase 1/2 Active not recruiting

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms, Disease Progression

NCT05426005 2026-05-22

Cadonilimab for PD-1/PD-L1 Blockade-refractory, MSI-H/dMMR, Advanced Colorectal Cancer

Phase 1/2 Recruiting

Gastrointestinal

Turcot syndrome, Diabetes Mellitus, Insulin-Dependent, 12, Colorectal Neoplasms

NCT06305247 2026-05-20

A Study to Assess IPN01194 When Administered Alone in Adults With Advanced Solid Tumours

Phase 1/2 Active not recruiting

DermatologicGastrointestinalHead & Neck

Squamous Cell Carcinoma of Head and Neck, Melanoma, Colorectal Neoplasms

NCT07540572 2026-05-20

A Study to Investigate the Safety, Pharmacokinetics, and Preliminary Efficacy of IDE574 Therapy in Adult Participants With Advanced Solid Tumors

Phase 1/2 Recruiting

GastrointestinalThoracic

Carcinoma, Non-Small-Cell Lung, Spinocerebellar Degenerations, Colorectal Neoplasms

NCT07587619 2026-05-20

Intraoperative Use of Oxygen Saturation Imaging to Assess Intestinal Perfusion

Phase 1/2 Active not recruiting

Gastrointestinal

Colorectal Neoplasms

NCT05726864 2026-05-19

AMPLIFY-7P

Phase 1/2 Active not recruiting

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT04421820 2026-05-18

BOLD-100 in Combination With FOLFOX for the Treatment of Advanced Solid Tumours

Phase 1/2 Recruiting

Gastrointestinal

Pancreatic Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Cholangiocarcinoma

NCT07591597 2026-05-18

IGNITE-CRC

Phase 1/2 Not yet recruiting

Gastrointestinal

Colorectal Neoplasms

NCT05379985 2026-05-15

Study of RMC-6236 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS

Phase 1/2 Recruiting

DermatologicGastrointestinalThoracic

Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Gastrointestinal Neoplasms, Intestinal Neoplasms, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Neoplastic Processes, Pancreatic Neoplasms, Thoracic Neoplasms, Colorectal Neoplasms, Carcinoma, Pancreatic Ductal

NCT07589517 2026-05-15

DUO-CRC-NK-111

Phase 1/2 Recruiting

Gastrointestinal

Colorectal Neoplasms