Clinical Trials

64 enrolled

Colonic Neoplasms, Neoplasm Metastasis, Rectal Neoplasms, Colorectal Neoplasms

NCT02465060 2026-06-03

Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial)

BreastCNSDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckLymphoidOther hematologic neoplasmPlasma cellThoracic

6,452 enrolled 1 FDA

Urinary Bladder Neoplasms, Breast Neoplasms, Carcinoma, Renal Cell, Uterine Cervical Neoplasms, Colonic Neoplasms, Esophageal Neoplasms, Glioma, Carcinoma, Hepatocellular, Lung Neoplasms, Lymphoma, Melanoma, Multiple Myeloma, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Rectal Neoplasms, Stomach Neoplasms, Thyroid Neoplasms, Uterine Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms, Hematologic Neoplasms

NCT05546476 2026-06-03

PROACC-1

187 enrolled 24 charts

GastrointestinalThoracic

Anorexia, Cachexia, Carcinoma, Non-Small-Cell Lung, Fatigue, Neoplasms, Pancreatic Neoplasms, Colorectal Neoplasms, Weight Loss

NCT07622550 2026-06-03

A Single-arm, Multicenter Clinical Study of Fruquintinib Combined With Serplulimab and Chemotherapy as First-line Treatment for Patients With RAS/BRAF-mutated Advanced Colorectal Cance

80 enrolled

Colorectal Neoplasms

NCT07623642 2026-06-03

A Phase II Study of GV20-0251 in Combination With Anti-PD-1 Monoclonal Antibodies in Patients With Unresectable, Locally Advanced, or Metastatic Solid Tumors.

BreastGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

227 enrolled

Squamous Cell Carcinoma of Head and Neck, Esophageal Squamous Cell Carcinoma, Carcinoma, Non-Small-Cell Lung, Uterine Cervical Neoplasms, Gallbladder Neoplasms, Prostatic Neoplasms, Colorectal Neoplasms, Cholangiocarcinoma, Small Cell Lung Carcinoma, Triple Negative Breast Neoplasms

NCT06692959 2026-06-02

Neo-POLEM

Phase 2 Terminated

3 enrolled

Colorectal Neoplasms

NCT06820463 2026-06-02

AndroMETa-CRC

390 enrolled

Colorectal Neoplasms

NCT07023289 2026-06-02

A Study to Assess Adverse Events and Change in Disease Activity in Adult Participants Receiving Intravenously Infused Telisotuzumab Adizutecan Alone or With Standard of Care in Participants With Post Adjuvant Circulating Tumor DNA Positive Colorectal Cancer and No Radiographic Evidence of Disease

140 enrolled

Neoplasms, Colorectal Neoplasms

NCT07621497 2026-06-02

FOLFOX8 Versus mFOLFOX6 With Bevacizumab or Cetuximab for First-Line Unresectable Metastatic Colorectal Cancer (Phase II)

229 enrolled

Colorectal Neoplasms

NCT03935893 2026-06-01

Adoptive Transfer of Tumor Infiltrating Lymphocytes for Advanced Solid Cancers

DermatologicEndocrineGastrointestinalNETOther solid neoplasmSarcomaThoracic

20 enrolled

Turcot syndrome, Mesothelioma, Pancreatic Neoplasms, Sarcoma, Stomach Neoplasms, Colorectal Neoplasms, Carcinoma, Merkel Cell, Neoplasms, Squamous Cell, Neuroendocrine Tumors, Microsatellite Instability

NCT05411718 2026-06-01

A Phase IIa Randomized, Double-Blinded Clinical Trial of Naproxen or Aspirin for Cancer Immune Interception in Lynch Syndrome

40 enrolled

Colorectal Neoplasms, Hereditary Nonpolyposis, Colorectal Neoplasms

NCT06607458 2026-06-01

DEL-LIVER

90 enrolled

Rectal Neoplasms, Colorectal Neoplasms

NCT06680739 2026-06-01

SERPENTINE

GastrointestinalGynecologic

60 enrolled

Colorectal Neoplasms, Endometrial Neoplasms

NCT07136077 2026-06-01

A Phase 2 Trial of Fruquintinib and Tislelizumab in ctDNA-defined Minimal Residual Disease in Colorectal Cancer After Completion of Adjuvant Chemotherapy

20 enrolled

Colorectal Neoplasms, Neoplasm, Residual

NCT07612007 2026-06-01

HRX215, A First Generation MKK4 Inhibitor Drug, for the Treatment of Patients With Colorectal Liver Metastasis After Undergoing a Portal Vein Embolization

80 enrolled

Colorectal Neoplasms

NCT03693170 2026-05-29

ANCHOR-CRC

95 enrolled 30 charts

Colorectal Neoplasms

NCT05185947 2026-05-29

Intravenous and Intraperitoneal Paclitaxel and Oral Nilotinib for Peritoneal Carcinomatosis

BreastGastrointestinalGynecologic

21 enrolled 21 charts

Appendiceal Neoplasms, Breast Neoplasms, Genital Neoplasms, Female, Ovarian Neoplasms, Peritoneal Neoplasms, Colorectal Neoplasms, Cholangiocarcinoma

NCT06848348 2026-05-29

Efficacy and Safety Study of Halneuron in the Treatment of Chemotherapy-Induced Neuropathic Pain

240 enrolled

BreastGastrointestinal

Cancer Pain, Breast Neoplasms, Neoplasms, Neuralgia, Pain, Peripheral Nervous System Diseases, Colorectal Neoplasms

NCT02134925 2026-05-28

Vaccine Therapy in Treating Patients With Newly Diagnosed Advanced Colon Polyps

110 enrolled 12 charts

Colorectal Neoplasms

NCT02965703 2026-05-28

Aspirin in Preventing Colorectal Cancer in Patients With Colorectal Adenoma

81 enrolled 13 charts

Colorectal Neoplasms

NCT02568267 2026-05-27

STARTRK-2

BreastCNSDermatologicEndocrineGastrointestinalGenitourinaryGynecologicHead & NeckLymphoidNETSarcomaThoracic

534 enrolled 1 FDA

Thyroid Cancer, Papillary, Brain Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Head and Neck Neoplasms, Melanoma, Ovarian Neoplasms, Pancreatic Neoplasms, Salivary Gland Neoplasms, Sarcoma, Colorectal Neoplasms, Lymphoma, Large-Cell, Anaplastic, Cholangiocarcinoma, Neuroendocrine Tumors

NCT05419011 2026-05-27

Testing a Combination of Vaccines for Cancer Prevention in Lynch Syndrome

186 enrolled

Colorectal Neoplasms, Hereditary Nonpolyposis, Colorectal Neoplasms

NCT02350530 2026-05-22

FORBES

138 enrolled

Colorectal Neoplasms

NCT04007770 2026-05-22

Acupuncture Pilot Study for Cancer-related Cognitive Function

BreastGastrointestinalGenitourinary

48 enrolled

Breast Neoplasms, Prostatic Neoplasms, Colorectal Neoplasms

NCT05571293 2026-05-22

NEST-1

26 enrolled 15 charts

Diabetes Mellitus, Insulin-Dependent, 12, Colorectal Neoplasms

NCT06903858 2026-05-22

PICC-3

105 enrolled

Turcot syndrome, Colorectal Neoplasms

NCT07235293 2026-05-22

A Study to Test DSP107 in Combination With Atezolizumab in Comparison With Fruquintinib as a New Treatment for Colorectal Cancer.

90 enrolled

Colorectal Neoplasms

NCT07604909 2026-05-22

A Phase II Randomized Trial of Serplulimab With Second-Line Chemo/Targeted Therapy for Early Relapse Colorectal Cancer After Adjuvant Chemotherapy

40 enrolled

Recurrence, Colorectal Neoplasms

NCT03722680 2026-05-20

RILUZOX-01

Phase 2 Suspended

80 enrolled

Colorectal Neoplasms

NCT04787341 2026-05-20

PARERE

214 enrolled

Colorectal Neoplasms

NCT06959550 2026-05-20

Phase II Study of Anti-PD-1/VEGF Bispecific Antibody Ivonescimab in Patients With Previously Treated Metastatic Colorectal Cancer

90 enrolled

Colorectal Neoplasms

NCT07359456 2026-05-19

COLIBRI-GI

130 enrolled

Colorectal Neoplasms

NCT06699836 2026-05-18

CLOVER

66 enrolled

Colorectal Neoplasms

NCT06824064 2026-05-18

VISTA-1

150 enrolled

Neoplasm Metastasis, Colorectal Neoplasms

NCT06948448 2026-05-18

A Study to Evaluate the Safety and Efficacy of Two Dose Levels of ONO-4578 With Opdivo®, in Combination With mFOLFOX6 and Bevacizumab Versus Standard of Care in Participants With Non-MSI-H/dMMR, PD-L1 Positive Advanced Colorectal Cancer

144 enrolled

Colorectal Neoplasms

NCT07285044 2026-05-18

The Cancer Connected Access and Remote Expertise Beyond Walls Program to Provide In-Home Cancer Treatment and Improve Treatment Satisfaction in Cancer Patients Living in the Florida Panhandle and Surrounding Areas

BreastCNSDermatologicGastrointestinalGenitourinaryGynecologicLymphoidMyeloidPlasma cellThoracic

27 enrolled

Amyloidosis, Urinary Bladder Neoplasms, Breast Neoplasms, Carcinoma, Basal Cell, Carcinoma, Renal Cell, Carcinoma, Squamous Cell, Carcinoma, Transitional Cell, Uterine Cervical Neoplasms, Fallopian Tube Neoplasms, Glioblastoma, Carcinoma, Hepatocellular, Hodgkin Disease, Lung Neoplasms, Melanoma, Multiple Myeloma, Myelodysplastic Syndromes, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Colorectal Neoplasms, Carcinoma, Merkel Cell, Endometrial Neoplasms, Lymphoma, Mantle-Cell

NCT06300463 2026-05-15

Platform Study of Immunotherapy Combinations in Colorectal Cancer Liver Metastases

24 enrolled

Colorectal Neoplasms

NCT07551596 2026-05-15

Testing the Combination of Anti-Cancer Drugs, Botensilimab (AGEN1181) and Balstilimab (AGEN2034), After Standard Treatment for Colorectal Cancer, Combat Trial

20 enrolled

Colorectal Neoplasms

NCT04486378 2026-05-14

A Phase II Clinical Trial Comparing the Efficacy of RO7198457 Versus Watchful Waiting in Patients With ctDNA-positive, Resected Stage II (High Risk) and Stage III Colorectal Cancer

327 enrolled

Neoplasms, Colorectal Neoplasms

NCT05223036 2026-05-14

Testing Obeticholic Acid for Familial Adenomatous Polyposis

Phase 2 Terminated

15 enrolled

Attenuated familial adenomatous polyposis, Duodenal Neoplasms, Adenomatous Polyposis Coli, Colorectal Neoplasms

NCT07586813 2026-05-14

N01-A-PICIT-GI