Announcements Trials
Browse Landscape

Phase

Phase 1 2Phase 2 1

Status

Completed 3

Sponsor Class

NIH 3INDUSTRY 3OTHER 1

Study Type

Interventional 3

Sponsor

Cancer Type

Gastrointestinal 3

Conditions

Neurofibromatosis 1 4Melanoma 4Pancreatic Neoplasms 3Neurofibroma, Plexiform 3Colorectal Neoplasms 3Carcinoma, Hepatocellular 3Rectal Neoplasms 2Colonic Neoplasms 2Carcinoma, Non-Small-Cell Lung 2Bile Duct Neoplasms 2Adult Solid Neoplasm 2Uveal Melanoma 1Thyroid Neoplasms 1Thyroid Cancer, Papillary 1Thymoma 1Small Cell Lung Carcinoma 1Sarcoma 1Peripheral Nervous System Diseases 1Pain 1Neuroblastoma 1Neoplasms, Nerve Tissue 1Myelodysplastic-Myeloproliferative Diseases 1Myelodysplastic Syndromes 1Multiple Myeloma 1Lymphoma, Non-Hodgkin 1Lymphoma, Large B-Cell, Diffuse 1Lung Neoplasms 1Leukemia, Promyelocytic, Acute 1Leukemia, Myeloid, Acute 1Heredodegenerative Disorders, Nervous System 1

Interventions

Fluorouracil 61Leucovorin 56Oxaliplatin 36Irinotecan 27Specimen Handling 23Biopsy 20Chemotherapy, Adjuvant 17Capecitabine 14Cetuximab 13Magnetic Resonance Spectroscopy 12Folfox protocol 12Bevacizumab 12Neoadjuvant Therapy 10sargramostim 6aldesleukin 6Melphalan 6Radiotherapy 5Floxuridine 5Cyclophosphamide 5dehydroftorafur 4X-Rays 4Nivolumab 4Interferon-alpha 4Immunoglobulin G 4Gemcitabine 4Disulfides 4Celecoxib 4fludarabine 3durvalumab 3Trastuzumab 3

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
NIH × Colorectal Neoplasms × AZD 6244 × Clear all
NCT02188264 2025-02-11

Selumetinib and Cyclosporine in Treating Patients With Advanced Solid Tumors or Advanced or Metastatic Colorectal Cancer

National Cancer Institute (NCI)

Phase 1 Completed
40 enrolled
Gastrointestinal

Colorectal Neoplasms

NCT01287130 2019-12-17

AZD6244 With Cetuximab for Solid Tumors and Colorectal Cancer

National Institutes of Health Clinical Center (CC)

Phase 1 Completed
10 enrolled
Gastrointestinal

Colonic Neoplasms, Colorectal Neoplasms

NCT01333475 2015-09-30

MK-2206 and AZD6244 in Patients With Advanced Colorectal Carcinoma

National Institutes of Health Clinical Center (CC)

Phase 2 Completed
21 enrolled 11 charts
Gastrointestinal

Colorectal Neoplasms

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