Clinical Trials Browser

Colorectal Neoplasms × Folfox protocol × Clear all

NCT07284849 2026-04-16

A Study to Evaluate the Efficacy and Safety of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal Cancer

Phase 3 Recruiting

Gastrointestinal

Colonic Neoplasms, Colorectal Neoplasms

NCT06625775 2026-04-13

Open-Label Study of BBO-10203 in Subjects With Advanced Solid Tumors

Phase 1 Recruiting

BreastGastrointestinalThoracic

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Neoplasm Metastasis, Colorectal Neoplasms

NCT06663319 2026-04-13

A Study of JNJ-89402638 for Metastatic Colorectal and Gastric Cancers

Phase 1 Recruiting

Gastrointestinal

Gastrointestinal Neoplasms, Colorectal Neoplasms

NCT04929223 2026-03-31

A Study Evaluating the Safety and Efficacy of Targeted Therapies in Subpopulations of Patients With Metastatic Colorectal Cancer (INTRINSIC)

Phase 1 Recruiting

Gastrointestinal

Colorectal Neoplasms

NCT07221357 2026-03-31

A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy Versus Bevacizumab in Combination With Chemotherapy in Participants With Previously Untreated, Unresectable, or Metastatic Colorectal Cancer

Phase 2/3 Recruiting

Gastrointestinal

Colorectal Neoplasms

NCT07500298 2026-03-30

Phase 1 Study Of SAR445877 In Combination With FOLFOX6 And Bevacizumab As First-Line Treatment For Microsatellite Stable Metastatic Colorectal Cancer

Phase 1 Not yet recruiting

Gastrointestinal

Colorectal Neoplasms

NCT06917079 2026-03-23

BBO-11818 in Adult Subjects With KRAS Mutant Cancer

Phase 1 Recruiting

GastrointestinalThoracic

Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis, Colorectal Neoplasms

NCT06179160 2026-03-16

A Study to Evaluate INCB161734 in Participants With Advanced or Metastatic Solid Tumors With KRAS G12D Mutation

Phase 1 Recruiting

GastrointestinalThoracic

Carcinoma, Non-Small-Cell Lung, Colorectal Neoplasms

NCT07318389 2026-02-27

ASCEND-CRC: Profiling and Targeting Dynamic Tumor Resistance in Patients With Metastatic Colorectal Cancer

Phase EARLY_PHASE1 Not yet recruiting

Gastrointestinal

Colorectal Neoplasms

NCT07323576 2026-02-09

INAVO-CRC

Phase 2 Withdrawn

Gastrointestinal

Colorectal Neoplasms

NCT00208260 2026-02-05

Intensified Chemotherapy in CRC After Resection of Liver Metastases

Phase 2/3 Completed

Gastrointestinal

Colorectal Neoplasms

NCT07389265 2026-02-05

CAPRI-3 GOIM

Phase 3 Recruiting

Gastrointestinal

Colorectal Neoplasms

NCT07340567 2026-01-14

CIRCULATEIII

Phase 3 Not yet recruiting

Gastrointestinal

Colorectal Neoplasms

NCT06106308 2026-01-12

Study of Onvansertib in Combination With FOLFIRI and Bevacizumab or FOLFOX and Bevacizumab Versus FOLFIRI and Bevacizumab or FOLFOX and Bevacizumab for First-Line Treatment of Metastatic Colorectal Cancer in Adult Participants With a KRAS or NRAS Mutation

Phase 2 Active not recruiting

Gastrointestinal

Colorectal Neoplasms

NCT06838338 2026-01-08

JAB-21822 Combined With Chemotherapy and Bevacizumab in Second-line KRAS G12C CRC

Phase 1 Active not recruiting

Gastrointestinal

Colorectal Neoplasms

NCT07309289 2025-12-30

NALIRIFOX Plus Targeted Therapy Versus FOLFOX Plus Targeted Therapy as First-line Treatment for Metastatic Colorectal Cancer

Phase 3 Recruiting

Gastrointestinal

Colorectal Neoplasms

NCT06783491 2025-11-24

FOXHIPECT4

Phase 3 Not yet recruiting

Gastrointestinal

Colorectal Neoplasms

NCT04595266 2025-09-29

LIVERPEARL

Phase 2 Active not recruiting

Gastrointestinal

Colorectal Neoplasms

NCT06936527 2025-09-03

XS-03-II201

Phase 1/2 Enrolling by invitation

Gastrointestinal

Colorectal Neoplasms

NCT07106034 2025-08-12

ONTOP

Phase 2 Not yet recruiting

Gastrointestinal

Colorectal Neoplasms

NCT05480306 2025-08-03

DeFianCe

Phase 2 Completed

Gastrointestinal

Colonic Neoplasms, Colorectal Neoplasms

NCT03186326 2025-06-29

SAMCO

Phase 2 Completed

Gastrointestinal

Colorectal Neoplasms

NCT03584711 2025-06-29

OPTIPRIME

Phase 2 Completed

Gastrointestinal

Colorectal Neoplasms

NCT00873275 2025-06-22

Ursodiol, Combination Chemotherapy, and Bevacizumab in Treating Patients With Stage IV Colorectal Cancer

Phase 1 Completed

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT06991465 2025-05-28

Hypo-OPRA

Phase 2 Recruiting

Gastrointestinal

Colorectal Neoplasms

NCT06907342 2025-05-25

COSENSE-1

Phase 2 Recruiting

Gastrointestinal

Colorectal Neoplasms

NCT03597581 2025-04-03

A Study of RGX-202-01 (Ompenaclid) as Combination Therapy in RAS Mutant Advanced Colorectal Cancer

Phase 1 Completed

Gastrointestinal

Gastrointestinal Neoplasms, Stomach Neoplasms, Colorectal Neoplasms

NCT00059930 2025-03-26

Adjuvant Hepatic Arterial Infusion and Combination Chemotherapy in Treating Patients With Resectable Hepatic Metastases From Colorectal Cancer

Phase 1 Completed

Gastrointestinal

Colonic Neoplasms, Neoplasm Metastasis, Rectal Neoplasms, Colorectal Neoplasms

NCT06225843 2025-02-19

EGIA-003

Phase 2 Recruiting

Gastrointestinal

Colorectal Neoplasms

NCT06833866 2025-02-19

Phase I Trial of 5-Fluorouracil (5FU) -Based Therapy in Combination With Hydroxytyrosol (HT) in Patients With Advanced or Metastatic Colorectal Cancer

Phase 1 Recruiting

Gastrointestinal

Colorectal Neoplasms

NCT02162563 2025-02-06

CAIRO5

Phase 3 Completed

Gastrointestinal

Colorectal Neoplasms

NCT03117972 2025-02-05

CLavSyn

Phase 2 Terminated

Gastrointestinal

Colorectal Neoplasms

NCT01878422 2025-01-31

ITACa

Phase 3 Completed

Gastrointestinal

Colorectal Neoplasms

NCT03526835 2025-01-29

A Study of Bispecific Antibody MCLA-158 in Patients With Advanced Solid Tumors

Phase 1/2 Recruiting

GastrointestinalHead & Neck

Squamous Cell Carcinoma of Head and Neck, Esophageal Neoplasms, Stomach Neoplasms, Colorectal Neoplasms

NCT06475352 2025-01-27

FUDOSE

Phase 2 Recruiting

Gastrointestinal

Gastrointestinal Neoplasms, Neoplasm Metastasis, Neoplasms, Recurrence, Colorectal Neoplasms

NCT01167725 2024-12-27

Standard Therapy With or Without Surgery and Mitomycin C in Treating Patients With Advanced Limited Peritoneal Dissemination of Colon Cancer

Phase 3 Terminated

Gastrointestinal

Colonic Neoplasms, Colorectal Neoplasms

NCT05462613 2024-12-20

REPROGRAM-02

Phase 2/3 Recruiting

Gastrointestinal

Colorectal Neoplasms

NCT02009449 2024-11-15

IVY

Phase 1 Completed

BreastDermatologicGastrointestinalGenitourinaryGynecologicThoracic

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Melanoma, Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Colorectal Neoplasms

NCT04516681 2024-10-24

Combination of IV Ascorbic Acid and Adebrelimab in Metastatic Colorectal Cancer

Phase 3 Recruiting

Gastrointestinal

Colorectal Neoplasms

NCT03635021 2024-10-21

CR-SEQUENCE

Phase 3 Active not recruiting

Gastrointestinal

Colorectal Neoplasms

NCT06509880 2024-07-19

ISMCC

Phase 1/2 Active not recruiting

Gastrointestinal

Colorectal Neoplasms

NCT05039944 2024-07-18

SI-B001 as a Single Agent or in Combination With Chemotherapy in the Treatment of Digestive System Malignancies

Phase 2 Terminated

Gastrointestinal

Colorectal Neoplasms

NCT03043950 2024-04-24

VALIDATE

Gastrointestinal

Colorectal Neoplasms

NCT01515787 2024-02-02

PROSPECT: Chemotherapy Alone or Chemotherapy Plus Radiation Therapy in Treating Patients With Locally Advanced Rectal Cancer Undergoing Surgery

Phase 2/3 Unknown

1,194 enrolled 25 charts

Gastrointestinal

Rectal Neoplasms, Colorectal Neoplasms

NCT06218810 2024-01-23

Cadonilimab in Combination With Bevacizumab and FOLFOX Regimen for the First-Line Treatment of Advanced Unresectable MSS-Type, RAS-Mutated Metastatic Colorectal Cancer

Phase 2 Recruiting

Gastrointestinal

Colorectal Neoplasms

NCT06115174 2023-11-02

CRC - PTX

Phase 4 Unknown

Gastrointestinal

Colorectal Neoplasms

NCT00958737 2023-09-29

IDEA

Phase 3 Unknown

Gastrointestinal

Colonic Neoplasms, Colorectal Neoplasms

NCT01622543 2023-08-23

Reolysin in Combination With FOLFOX6 and Bevacizumab or FOLFOX6 and Bevacizumab Alone in Metastatic Colorectal Cancer

Phase 2 Completed

109 enrolled 13 charts

Gastrointestinal

Colorectal Neoplasms

NCT06003998 2023-08-22

INTERACT-II

Phase 2 Unknown

Gastrointestinal

Colorectal Neoplasms

NCT05832398 2023-06-28

Precision Chemotherapy Based on Organoid Drug Sensitivity for Colorectal Cancer

Phase NA Unknown

Gastrointestinal

Colorectal Neoplasms