Announcements Trials
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Phase

Phase 2 2Phase 1 2Phase 3 1Phase 2/3 1

Status

Completed 6Unknown 5

Sponsor Class

OTHER 4NIH 1NETWORK 1

Study Type

Interventional 6

Sponsor

Cancer Type

Gastrointestinal 6

Conditions

Polycystic Ovary Syndrome 11Carcinoma, Non-Small-Cell Lung 9Recurrence 7Colorectal Neoplasms 6Ovarian Neoplasms 4Neoplasm Metastasis 4Lymphoma, T-Cell, Peripheral 4Colonic Neoplasms 4Rectal Neoplasms 3Lymphoma, T-Cell 3Lung Neoplasms 3Sezary Syndrome 2Mycosis Fungoides 2Meningeal Carcinomatosis 2Lymphoma, T-Cell, Cutaneous 2Lymphoma, B-Cell 2Lymphoma 2Infertility 2Hyperandrogenism 2Head and Neck Neoplasms 2Breast Neoplasms 2Atypical Squamous Cells of the Cervix 2Anovulation 2Adenoma 2Waldenstrom Macroglobulinemia 1Uterine Cervical Neoplasms 1Uterine Cervical Dysplasia 1Urinary Bladder Neoplasms 1Thyroid Diseases 1Thrombocytopenia 1

Interventions

Fluorouracil 255Leucovorin 224Oxaliplatin 218Irinotecan 206Bevacizumab 200Capecitabine 144Cetuximab 136Panitumumab 68Folfox protocol 63regorafenib 50Colonoscopy 44pembrolizumab 42IFL protocol 39Radiotherapy 32Nivolumab 31Drug Therapy 27trifluridine tipiracil drug combination 26Gemcitabine 24Blood Specimen Collection 23Chemotherapy, Adjuvant 20Surveys and Questionnaires 19Celecoxib 19Surgical Procedures, Operative 16durvalumab 15Neoadjuvant Therapy 15Cyclophosphamide 14Cisplatin 14aflibercept 13Standard of Care 13Pemetrexed 13

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

6 trials
RecentStart dateEnrollment
Completed × Colorectal Neoplasms × Folic Acid × Clear all
NCT00002650 2023-06-22

High-Dose Folic Acid in Preventing Colorectal Cancer in Patients Who Have Had Polyps Surgically Removed

Eastern Cooperative Oncology Group

Phase 2 Completed
80 enrolled
Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT01328171 2023-06-15

VOLFI

AIO-Studien-gGmbH

Phase 2 Completed
93 enrolled
Gastrointestinal

Colorectal Neoplasms

NCT00272324 2020-03-13

Aspirin/Folate Prevention of Large Bowel Polyps

Dartmouth-Hitchcock Medical Center

Phase 2/3 Completed
1,121 enrolled
Gastrointestinal

Adenoma, Polyps, Colorectal Neoplasms, Adenomatous Polyps

NCT00973609 2015-09-01

Optimal Maintenance Therapy With Bevacizumab After Induction in Metastatic Colorectal Cancer (CRC)

AIO-Studien-gGmbH

Phase 3 Completed
853 enrolled
Gastrointestinal

Colorectal Neoplasms

NCT00096330 2014-01-13

Folate-Depleted Diet Compared With Folate-Supplemented Diet in Preventing Colorectal Cancer in Patients at High Risk for Colorectal Cancer

Roswell Park Cancer Institute

Phase 1 Completed
20 enrolled
Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00611000 2009-02-17

Effect of Folate on DNA in Colon Tissue and Blood Samples From Patients at Increased Risk of Developing Colorectal Neoplasia

National Cancer Institute (NCI)

Phase 1 Completed
20 enrolled
Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

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