Announcements Trials
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Phase

Phase 2 2Phase 1/2 2Phase 3 1

Status

Completed 5Recruiting 4Unknown 2Withdrawn 1Terminated 1Active not recruiting 1

Sponsor Class

INDUSTRY 3OTHER 2

Study Type

Interventional 5

Sponsor

Cancer Type

Gastrointestinal 5

Conditions

Colorectal Neoplasms 5Colonic Neoplasms 3Rectal Neoplasms 2Neoplasm Metastasis 2Malignant Solid Tumour 1Intestinal Neoplasms 1Gastrointestinal Neoplasms 1Gastrointestinal Diseases 1Digestive System Neoplasms 1

Interventions

Fluorouracil 255Leucovorin 224Oxaliplatin 218Irinotecan 206Bevacizumab 200Capecitabine 144Cetuximab 136Panitumumab 68Folfox protocol 63regorafenib 50Colonoscopy 44pembrolizumab 42IFL protocol 39Radiotherapy 32Nivolumab 31Drug Therapy 27trifluridine tipiracil drug combination 26Gemcitabine 24Blood Specimen Collection 23Chemotherapy, Adjuvant 20Surveys and Questionnaires 19Celecoxib 19Surgical Procedures, Operative 16durvalumab 15Neoadjuvant Therapy 15Cyclophosphamide 14Cisplatin 14aflibercept 13Standard of Care 13Pemetrexed 13

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
Completed × Colorectal Neoplasms × Levoleucovorin × Clear all
NCT03428958 2025-04-23

A Safety, Pharmacokinetic and Efficacy Study of NUC-3373 in Combination With Standard Agents Used in Colorectal Cancer Treatment

NuCana plc

Phase 1/2 Completed
111 enrolled 22 charts
Gastrointestinal

Colonic Neoplasms, Colorectal Neoplasms

NCT04456699 2024-10-29

LYNK-003

Merck Sharp & Dohme LLC

Phase 3 Completed
335 enrolled 19 charts
Gastrointestinal

Colorectal Neoplasms

NCT03698461 2024-01-31

CLIMB

Asan Medical Center

Phase 2 Completed
20 enrolled
Gastrointestinal

Colonic Neoplasms, Neoplasm Metastasis, Rectal Neoplasms, Colorectal Neoplasms

NCT01681472 2020-09-25

PK/PD Investigation of Modufolin (Arfolitixorin) in Plasma, Tumor and Adjacent Mucosa Adjacent Mucosa in Patients With Colon Cancer

Isofol Medical AB

Phase 1/2 Completed
32 enrolled 52 charts
Gastrointestinal

Colonic Neoplasms, Digestive System Neoplasms, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Intestinal Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00865709 2014-12-11

Study of Modified FOLFOX6 Plus or Minus Sorafenib in Stage IV Metastatic Colorectal Carcinoma (mCRC) Subjects

Bayer

Phase 2 Completed
198 enrolled 18 charts
Gastrointestinal

Neoplasm Metastasis, Colorectal Neoplasms

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