Clinical Trials

Colorectal Neoplasms

NCT06991465 2025-05-28

Hypo-OPRA

Phase 2 Recruiting

35 enrolled

Colorectal Neoplasms

NCT03135652 2024-01-03

Consolidative Radiotherapy for Colorectal Cancer Liver Metastases Receiving Surgery or Radiofrequency Ablation

Phase 2 Withdrawn

Colorectal Neoplasms

NCT06120127 2023-11-07

IMPROVE

80 enrolled

Phase 2 Not yet recruiting

Colorectal Neoplasms

NCT06099951 2023-10-25

Total Neoadjuvant Treatment for pMMR Locally Advanced Low Rectal Cancer: Anti-PD-1 Antibody With FOLFOXIRI and Preoperative Radiation Therapy

53 enrolled

Colorectal Neoplasms

NCT02535988 2023-09-21

Abscopal Effect for Metastatic Colorectal Cancer

Phase 2 Withdrawn

Phase 2 Active not recruiting

Colorectal Neoplasms

NCT04304209 2023-02-01

Pd1 Antibody Sintilimab ± Chemoradiotherapy for Locally Advanced Rectal Cancer

195 enrolled

Colorectal Neoplasms

NCT00280761 2022-08-11

Biomarkers in Patients With Rectal Cancer Undergoing Chemotherapy and Radiation Therapy

Completed

47 enrolled

Rectal Neoplasms, Colorectal Neoplasms

NCT03122509 2022-07-06

A Clinical Trial of Durvalumab and Tremelimumab, Administered With Radiation Therapy or Ablation in Patients With Colorectal Cancer

25 enrolled 7 charts

Colorectal Neoplasms

NCT01759238 2022-07-01

OLGA

1 enrolled

Neoplasm Metastasis, Colorectal Neoplasms

NCT02121405 2022-05-11

PSSR

Phase 3 Suspended

350 enrolled

Radiation Injuries, Colorectal Neoplasms

NCT05292417 2022-03-31

Radiotherapy in Combination With Sintilimab，GM-CSF and Fruquintinib in Patients With MSS mCRC

71 enrolled

Colorectal Neoplasms

NCT05160727 2021-12-20

Radiotherapy Combined With Tislelizumab and Irinotecan in MSS/pMMR Recurrence and Metastatic Colorectal Cancer

44 enrolled

Colorectal Neoplasms

NCT00308516 2021-12-10

5-Fluorouracil, Bevacizumab, and Radiation Followed by Modified FOLFOX6 and Bevacizumab in Stage II/III Rectal Cancer

66 enrolled 6 charts

Rectal Neoplasms, Colorectal Neoplasms

NCT00227747 2021-02-17

Radiation Therapy and Capecitabine With or Without Oxaliplatin in Treating Patients Who Are Undergoing Surgery for Stage II or Stage III Rectal Cancer

Phase 3 Completed

598 enrolled

Rectal Neoplasms, Colorectal Neoplasms

NCT01224392 2020-12-30

RectumSIB

Phase 3 Completed

156 enrolled

Rectal Neoplasms, Colorectal Neoplasms

NCT02010567 2020-11-03

Neoadjuvant Chemoradiotherapy With CRLX-101 and Capecitabine for Rectal Cancer

Phase 1/2 Terminated

32 enrolled 18 charts

Rectal Neoplasms, Colorectal Neoplasms

NCT00021398 2020-06-05

Radiation Therapy and Chemotherapy Followed by Surgery and Combination Chemotherapy in Treating Patients With Rectal Cancer

23 enrolled

Rectal Neoplasms, Colorectal Neoplasms

NCT00541112 2020-02-11

Radiation Therapy, Chemotherapy, and Cetuximab Followed by Surgery, Chemotherapy, and Cetuximab in Treating Patients With Locally Advanced or Metastatic Rectal Cancer That Can Be Removed by Surgery

19 enrolled

Rectal Neoplasms, Colorectal Neoplasms

NCT00869570 2019-05-15

External-Beam Radiation Therapy, Capecitabine, and Sorafenib in Treating Patients With Locally Advanced Rectal Cancer

54 enrolled

Rectal Neoplasms, Colorectal Neoplasms

NCT03823079 2019-01-30

Comparison of Interleukin-11 and rhTPO for Recurrent Colorectal Cancer Patients With Thrombocytopenia

Classical hematologyGastrointestinal

50 enrolled

Thrombocytopenia, Colorectal Neoplasms

NCT00003344 2018-05-16

Radiation Therapy Plus Irinotecan in Treating Patients With Colon Cancer

49 enrolled

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00114231 2018-03-29

Capecitabine, Oxaliplatin, and Radiation Therapy in Treating Patients Who Are Undergoing Surgery for Stage I Rectal Cancer

90 enrolled 10 charts

Rectal Neoplasms, Colorectal Neoplasms

NCT00625183 2017-11-17

Capecitabine, Oxaliplatin, Selenomethionine, and Radiation Therapy in Treating Patients Undergoing Surgery For Newly Diagnosed Stage II or III Rectal Adenocarcinoma

5 enrolled 6 charts

Rectal Neoplasms, Colorectal Neoplasms

NCT00004005 2017-04-26

Irinotecan Followed By Fluorouracil and Leucovorin in Treating Patients With Stage III or Stage IV Colorectal Carcinoma (Cancer), Other Refractory Carcinoma, or Metastatic Adenoma (Cancer) of Unknown Primary Origin

12 enrolled

Colonic Neoplasms, Neoplasms, Unknown Primary, Rectal Neoplasms, Colorectal Neoplasms

NCT00081224 2016-12-15

Neoadjuvant Celecoxib and Capecitabine Combined With Pelvic Irradiation in Treating Patients With Stage II or Stage III Adenocarcinoma (Cancer) of the Rectum

3 enrolled

Rectal Neoplasms, Colorectal Neoplasms

NCT01263171 2016-09-21

COPERNICUS

60 enrolled

Rectal Neoplasms, Colorectal Neoplasms

NCT00023751 2016-07-06

Surgery With or Without Chemotherapy and Radiation Therapy in TreatingPatients With Stage I Rectal Cancer

320 enrolled

Rectal Neoplasms, Colorectal Neoplasms

NCT00296608 2016-05-30

Radiation Therapy With or Without Chemotherapy Before Surgery in Treating Patients With Stage II or Stage III Rectal Cancer

Phase 3 Completed

762 enrolled

Rectal Neoplasms, Colorectal Neoplasms

NCT00462501 2016-01-20

Combination Chemotherapy and Bevacizumab With or Without Radiation Therapy in Treating Patients With Locally Advanced Rectal Cancer

Phase NA Completed

35 enrolled 6 charts

Rectal Neoplasms, Colorectal Neoplasms

NCT00305643 2015-12-24

Celecoxib in Preventing Hand/Foot Syndrome Caused By Capecitabine With Metastatic Breast or Colorectal Cancer

Phase 3 Terminated

11 enrolled 7 charts

BreastGastrointestinal

Breast Neoplasms, Colonic Neoplasms, Pain, Rectal Neoplasms, Colorectal Neoplasms, Breast Neoplasms, Male, Hand-Foot Syndrome, Drug-Related Side Effects and Adverse Reactions

NCT00004891 2015-12-22

PET and CT Scans in Patients With Locally Advanced Primary Rectal Cancer That Can Be Removed During Surgery

Phase NA Completed

149 enrolled

Rectal Neoplasms, Colorectal Neoplasms

NCT00084773 2015-12-22

Neoadjuvant Cetuximab, Fluorouracil, and Pelvic Irradiation in Treating Patients With Locally Advanced or Locally Recurrent Rectal Cancer

Phase NA Completed

28 enrolled

Rectal Neoplasms, Colorectal Neoplasms

NCT00960427 2013-04-16

Studying Biomarkers in Tumor Tissue and Blood Samples From Patients Undergoing Chemotherapy and Radiation Therapy for Stage II or Stage III Rectal Cancer That Can Be Removed By Surgery

Phase 1 Withdrawn

BreastCNSGastrointestinalGenitourinaryHead & NeckThoracic

Rectal Neoplasms, Colorectal Neoplasms

NCT00897793 2013-04-12

Growth Factor Levels in the Blood of Patients Undergoing Radiation Therapy for Epithelial Cancer

Completed

25 enrolled

Squamous Cell Carcinoma of Head and Neck, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Head and Neck Neoplasms, Lung Neoplasms, Prostatic Neoplasms, Rectal Neoplasms, Salivary Gland Neoplasms, Colorectal Neoplasms, Esthesioneuroblastoma, Olfactory, Breast Neoplasms, Male, Small Cell Lung Carcinoma

NCT00086931 2013-03-08

Oxaliplatin, Capecitabine, and Radiation Therapy in Treating Patients With Locally Advanced Cancer of the Rectum

37 enrolled

Rectal Neoplasms, Colorectal Neoplasms

NCT00336960 2013-03-05

Celecoxib, Fluorouracil, and Radiation Therapy in Treating Patients With Stage II or Stage III Rectal Cancer That Can Be Removed By Surgery

24 enrolled

Rectal Neoplasms, Colorectal Neoplasms

NCT00280176 2012-02-14

Bortezomib, Fluorouracil, and External-Beam Radiation Therapy in Treating Patients With Stage II, Stage III, or Stage IV Rectal Cancer

Phase 1 Completed

11 enrolled

Rectal Neoplasms, Colorectal Neoplasms

NCT01016639 2011-10-17

CORGI

106 enrolled

Gallbladder Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms, Colorectal Neoplasms

NCT00725400 2011-07-20

Comparative Study of Cetuximab and Radiation Vs Surgery Before or After Radiation in Patients With Colorectal Carcinoma

Phase 2 Withdrawn

450 enrolled

Colorectal Neoplasms

NCT00084591 2010-02-12

Intensity-Modulated Radiation Therapy With Incorporated Boost and Capecitabine Before Surgery in Treating Patients With Locally Advanced Rectal Cancer

Phase 1 Completed

Rectal Neoplasms, Colorectal Neoplasms

NCT00383695 2010-01-13

EXPERT-C

164 enrolled