Announcements Trials
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Phase

Phase 1 8Phase 3 4Phase 2 2Phase 1/2 2

Status

Terminated 1Recruiting 1Not yet recruiting 1Active not recruiting 1

Sponsor Class

OTHER 2NIH 1NETWORK 1

Study Type

Interventional 4

Sponsor

Cancer Type

Gastrointestinal 4

Conditions

Colorectal Neoplasms 4Colonic Neoplasms 3Urinary Bladder Neoplasms 2Squamous Cell Carcinoma of Head and Neck 2Pancreatic Neoplasms 2Adenocarcinoma Of Esophagus 2Tongue Neoplasms 1Stage I Nasopharyngeal Keratinizing Squamous Cell Carcinoma AJCC v7 1Salivary Gland Neoplasms 1Pancreatic Intraductal Neoplasms 1PRETEXT I Hepatoblastoma 1Oropharyngeal Neoplasms 1Mouth Neoplasms 1Lymphoid Interstitial Pneumonia 1Laryngeal Neoplasms 1Hypopharyngeal Neoplasms 1Hepatoblastoma 1Fibrolamellar hepatocellular carcinoma 1DNA Repair-Deficiency Disorders 1Colorectal Neoplasms, Hereditary Nonpolyposis 1Clinical Stage I Esophageal Adenocarcinoma AJCC v8 1Carcinoma 1Appendiceal Neoplasms 1

Interventions

Fluorouracil 131Leucovorin 127Oxaliplatin 93Bevacizumab 86Irinotecan 74Capecitabine 63Cetuximab 47Folfox protocol 32Panitumumab 18regorafenib 16trifluridine tipiracil drug combination 15Drug Therapy 14Chemotherapy, Adjuvant 13IFL protocol 10Floxuridine 10Radiotherapy 9Tegafur 7Neoadjuvant Therapy 7Levoleucovorin 7Laparoscopy 7Aspirin 7pembrolizumab 6atezolizumab 6Trifluridine 6Celecoxib 6XELOX 5Mitomycin 5Colonoscopy 5tipiracil 4sintilimab 4

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
Phase 3 × Colorectal Neoplasms × dehydroftorafur × Clear all
NCT02997228 2026-06-03

Testing the Addition of Atezolizumab to Combination Chemotherapy or Atezolizumab Alone for Metastatic Colon or Rectal Cancer, the COMMIT Study

National Cancer Institute (NCI)

Phase 3 Active not recruiting
120 enrolled
Gastrointestinal

Colorectal Neoplasms

NCT05863195 2026-06-01

Testing Pump Chemotherapy in Addition to Standard of Care Chemotherapy Versus Standard of Care Chemotherapy Alone for Patients With Unresectable Colorectal Liver Metastases: The PUMP Trial

Eastern Cooperative Oncology Group

Phase 3 Recruiting
408 enrolled
Gastrointestinal

Colorectal Neoplasms

NCT07271355 2025-12-09

Pressurized Intraperitoneal Aerosolized Chemotherapy With Mitomycin for the Treatment of Unresectable Appendix or Colorectal Cancer With Peritoneal Metastases, The IMPACT Trial

City of Hope Medical Center

Phase 3 Not yet recruiting
129 enrolled
Gastrointestinal

Appendiceal Neoplasms, Colorectal Neoplasms

NCT03300609 2020-06-11

5-FU Based Maintenance Therapy in RAS Wild Type Metastatic Colorectal Cancer After Induction With FOLFOX Plus Panitumumab

University of Southern California

Phase 3 Terminated
4 enrolled
Gastrointestinal

Colorectal Neoplasms

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