Clinical Trials Browser

Phase 2/3 × Colorectal Neoplasms × Clear all

NCT07509398 2026-04-03

FMT Combined With Standard First-Line Therapy in Initially Unresectable Colorectal Cancer

Phase 2/3 Not yet recruiting

Gastrointestinal

Neoplasm Metastasis, Colorectal Neoplasms

NCT07221357 2026-03-31

A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy Versus Bevacizumab in Combination With Chemotherapy in Participants With Previously Untreated, Unresectable, or Metastatic Colorectal Cancer

Phase 2/3 Recruiting

Gastrointestinal

Colorectal Neoplasms

NCT02758951 2026-03-24

CAIRO6

Phase 2/3 Active not recruiting

GastrointestinalGynecologic

Hyperthermia, Colonic Neoplasms, Peritoneal Neoplasms, Colorectal Neoplasms

NCT07440290 2026-02-27

DETERMINE

Phase 2/3 Not yet recruiting

CNSEndocrineGastrointestinalGynecologicHead & NeckLymphoidMyeloidOther hematologic neoplasmPlasma cellThoracic

Thyroid Cancer, Papillary, Carcinoma, Non-Small-Cell Lung, Gastrointestinal Neoplasms, Glioma, Histiocytosis, Langerhans-Cell, Laryngeal Neoplasms, Lymphoproliferative Disorders, Multiple Myeloma, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Ovarian Neoplasms, Colorectal Neoplasms, Hematologic Neoplasms, Erdheim-Chester Disease, Thyroid Carcinoma, Anaplastic

NCT00208260 2026-02-05

Intensified Chemotherapy in CRC After Resection of Liver Metastases

Phase 2/3 Completed

Gastrointestinal

Colorectal Neoplasms

NCT04137107 2026-01-26

Duloxetine to Prevent Oxaliplatin-Induced Peripheral Neuropathy in Patients With Stage II-III Colorectal Cancer

Phase 2/3 Active not recruiting

Gastrointestinal

Colorectal Neoplasms

NCT07321847 2026-01-07

INJECTABL-3

Phase 2/3 Not yet recruiting

Gastrointestinal

Neoplasm Metastasis, Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT05786716 2025-12-02

DETERMINE

Phase 2/3 Recruiting

DermatologicGastrointestinalGenitourinaryGynecologicHead & NeckOther hematologic neoplasmThoracic

Urinary Bladder Neoplasms, Gallbladder Neoplasms, Lung Neoplasms, Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Salivary Gland Neoplasms, Skin Neoplasms, Colorectal Neoplasms, Hematologic Neoplasms

NCT05768178 2025-11-24

DETERMINE

Phase 2/3 Recruiting

CNSDermatologicEndocrineGastrointestinalGynecologicHead & NeckMyeloidOther hematologic neoplasmPlasma cellThoracic

Thyroid Cancer, Papillary, Carcinoma, Non-Small-Cell Lung, Glioma, Laryngeal Neoplasms, Melanoma, Multiple Myeloma, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Ovarian Neoplasms, Colorectal Neoplasms, Hematologic Neoplasms, Erdheim-Chester Disease, Thyroid Carcinoma, Anaplastic

NCT05770102 2025-11-24

DETERMINE

Phase 2/3 Recruiting

DermatologicGastrointestinalGynecologicLymphoid

Lymphoproliferative Disorders, Melanoma, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Colorectal Neoplasms, Endometrial Neoplasms

NCT05945901 2025-11-18

A Phase II/III Study of HR070803 in Combination With Oxaliplatin, 5-fluorouracil, Calcium Folinate and Bevacizumab Versus FOLFOX in Combination With Bevacizumab for First-line Treatment of Advanced Colorectal Cancer

Phase 2/3 Active not recruiting

Gastrointestinal

Colorectal Neoplasms

NCT07219238 2025-10-21

Study to Evaluate the Diagnostic Performance of GEH300079 (68Ga) Injection PET/CT for Detection of PC in Patients With Colorectal, Gastric, Ovarian, or Pancreatic Cancers (PERISCOPE)

Phase 2/3 Not yet recruiting

GastrointestinalGynecologic

Ovarian Neoplasms, Pancreatic Neoplasms, Peritoneal Neoplasms, Stomach Neoplasms, Colorectal Neoplasms

NCT06958419 2025-08-07

Node-Sparing Short-Course Radiotherapy Plus Chemotherapy, Bevacizumab and PD-1 Inhibitor in Metastatic pMMR/MSS Colorectal Cancer (MODIFI-CRC)

Phase 2/3 Recruiting

Gastrointestinal

Colorectal Neoplasms

NCT03326791 2025-07-31

ASAC

Phase 2/3 Active not recruiting

Gastrointestinal

Colorectal Neoplasms

NCT06441565 2025-07-30

Fruquintinib With or Without HAI-FOLFOX for Refractory Colorectal Cancer

Phase 2/3 Recruiting

Gastrointestinal

Colorectal Neoplasms

NCT06280495 2025-05-30

Neoadjuvant Serplulimab & Bevacizumab With FOLFOX vs. FOLFOX Alone in RAS/BRAF WT, pMMR/MSS CRC Patients

Phase 2/3 Recruiting

Gastrointestinal

Colorectal Neoplasms

NCT04856787 2025-05-18

A Clinical Studyf of SHR-1701 or Placebo in Combination With BP102 and XELOX in the First-line Treatment of mCRC

Phase 2/3 Terminated

Gastrointestinal

Colorectal Neoplasms

NCT05141721 2025-05-16

A Study of a Patient-Specific Neoantigen Vaccine in Combination With Immune Checkpoint Blockade for Patients With Metastatic Colorectal Cancer

Phase 2/3 Active not recruiting

Gastrointestinal

Colorectal Neoplasms

NCT06959693 2025-05-06

A Clinical Study to Evaluate the Efficacy and Safety of Envafolimab Combined With Cetuxima-βand mFOLFOX6 in Patients With MSS, RAS/BRAF Wild-Type Metastatic Colorectal Cancer (mCRC)

Phase 2/3 Not yet recruiting

Gastrointestinal

Colorectal Neoplasms

NCT05462613 2024-12-20

REPROGRAM-02

Phase 2/3 Recruiting

Gastrointestinal

Colorectal Neoplasms

NCT02494973 2024-10-28

PACHA-01

Phase 2/3 Completed

Gastrointestinal

Colorectal Neoplasms

NCT04547166 2024-10-17

A Clinical Study to Evaluate Efficacy and Safety of Serplulimab（HLX10） Combined With Bevacizumab（HLX04) and Chemotherapy (XELOX) in Patients With Metastatic Colorectal Cancer (mCRC)

Phase 2/3 Recruiting

Gastrointestinal

Colorectal Neoplasms

NCT06185556 2024-08-23

COLDFIRE-III

Phase 2/3 Recruiting

Gastrointestinal

Colorectal Neoplasms

NCT06243393 2024-07-10

TROPHIT1

Phase 2/3 Recruiting

Gastrointestinal

Colorectal Neoplasms

NCT01515787 2024-02-02

PROSPECT: Chemotherapy Alone or Chemotherapy Plus Radiation Therapy in Treating Patients With Locally Advanced Rectal Cancer Undergoing Surgery

Phase 2/3 Unknown

1,194 enrolled 25 charts

Gastrointestinal

Rectal Neoplasms, Colorectal Neoplasms

NCT03414983 2023-11-18

CheckMate 9X8

Phase 2/3 Completed

196 enrolled 26 charts

Gastrointestinal

Colorectal Neoplasms

NCT03742596 2023-03-15

Effect of Probiotics Supplementation on the Side Effects of Radiation Therapy Among Colorectal Cancer Patients

Phase 2/3 Withdrawn

Gastrointestinal

Colorectal Neoplasms

NCT05698082 2023-01-26

FOS Immunohistochemical Staining of Colorectal Cancer and Its Adjacent Tissues

Phase 2/3 Unknown

Gastrointestinal

Colorectal Neoplasms, Mpox, Monkeypox

NCT05409417 2022-06-08

Exploratory Study on Combined Conversion Immunotherapy for Liver Metastasis of MSS Type Initial Unresectable Colorectal Cancer Based on Gene Status

Phase 2/3 Unknown

Gastrointestinal

Colorectal Neoplasms

NCT03158610 2021-05-03

Biological-guided Metronomic Chemotherapy as Maintenance Strategy in Metastatic Colorectal Cancer

Phase 2/3 Terminated

Gastrointestinal

Colorectal Neoplasms

NCT02942706 2021-04-30

Cetuximab Maintenance Treatment Versus Continuation After Induction Therapy in mCRC

Phase 2/3 Unknown

Gastrointestinal

Colorectal Neoplasms

NCT03031444 2021-02-01

PARECEC

Phase 2/3 Completed

Gastrointestinal

Neoplasm Metastasis, Colorectal Neoplasms

NCT03909724 2020-11-13

SUNRISE-CRC

Phase 2/3 Unknown

Gastrointestinal

Neoplasm Metastasis, Colorectal Neoplasms

NCT00212615 2020-11-06

XELOX III. Xeloda in Combination With Eloxatin for Patients With Advanced or Metastatic Colorectal Cancer

Phase 2/3 Completed

Gastrointestinal

Neoplasm Metastasis, Colorectal Neoplasms

NCT04552093 2020-09-17

PUMP-IT

Phase 2/3 Unknown

Gastrointestinal

Colorectal Neoplasms

NCT00952029 2020-03-30

Combination Chemotherapy and Bevacizumab With or Without Bevacizumab Maintenance Therapy in Treating Patients With Metastatic Colorectal Cancer

Phase 2/3 Completed

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00272324 2020-03-13

Aspirin/Folate Prevention of Large Bowel Polyps

Phase 2/3 Completed

Gastrointestinal

Adenoma, Polyps, Colorectal Neoplasms, Adenomatous Polyps

NCT01741038 2020-01-22

AlloStim® In-Situ Vaccine in Pre-Treated Metastatic Colorectal Cancer

Phase 2/3 Withdrawn

Gastrointestinal

Colorectal Neoplasms

NCT01902823 2019-12-13

Effect of Cancer Nurse Navigators on Patient Outcomes

Phase 2/3 Terminated

BreastGastrointestinalGenitourinaryThoracic

Breast Neoplasms, Lung Neoplasms, Prostatic Neoplasms, Colorectal Neoplasms

NCT02332499 2019-05-21

ALTER0703

Phase 2/3 Completed

Gastrointestinal

Colorectal Neoplasms

NCT00647530 2019-05-17

FOxTROT

Phase 2/3 Unknown

Gastrointestinal

Colonic Neoplasms, Colorectal Neoplasms

NCT01550055 2019-04-10

CRC009

Phase 2/3 Completed

Gastrointestinal

Colorectal Neoplasms

NCT02284139 2018-04-23

Pilot Trial of EGF Ointment for the Patients With EGFR-i Related Skin Side Effects

Phase 2/3 Completed

GastrointestinalThoracic

Carcinoma, Non-Small-Cell Lung, Pancreatic Neoplasms, Colorectal Neoplasms

NCT01196260 2018-02-20

Combination Chemotherapy Treatments in Patients With Colorectal Cancer Stage II and III

Phase 2/3 Unknown

Gastrointestinal

Colorectal Neoplasms

NCT01646554 2017-05-09

BOS3

Phase 2/3 Withdrawn

Gastrointestinal

Colorectal Neoplasms

NCT00384176 2017-04-14

HORIZON III

Phase 2/3 Completed

1,814 enrolled 13 charts

Gastrointestinal

Colorectal Neoplasms

NCT01523431 2017-03-30

Individual Dosage Selection of Irinotecan (CPT-11) Based on UGT1A1 Genotype in Metastatic Colorectal Cancer Patients

Phase 2/3 Completed

Gastrointestinal

Diarrhea, Neutropenia, Colorectal Neoplasms

NCT00153816 2017-03-15

Vitamin D/Calcium Polyp Prevention Study

Phase 2/3 Completed

2,813 enrolled 15 charts

Gastrointestinal

Adenoma, Polyps, Colorectal Neoplasms, Adenomatous Polyps

NCT02978313 2016-11-30

Cetuximab Monotherapy Maintenance Treatment in mCRC

Phase 2/3 Unknown

Gastrointestinal

Colorectal Neoplasms

NCT02208804 2016-11-09

SIM

Phase 2/3 Unknown

Gastrointestinal

Digestive System Neoplasms, Liver Diseases, Neoplasm Metastasis, Colorectal Neoplasms