Clinical Trials Browser

Phase 2 × OTHER × Colorectal Neoplasms × Clear all

NCT05576896 2026-05-26

Hydroxychloroquine in Combination With Encorafenib and Cetuximab or Panitumumab in the Treatment of Metastatic BRAF-mutated Colorectal Cancer Refractory

Phase 2 Recruiting

Gastrointestinal

Colorectal Neoplasms

NCT02350530 2026-05-22

FORBES

Phase 2 Completed

Gastrointestinal

Colorectal Neoplasms

NCT04007770 2026-05-22

Acupuncture Pilot Study for Cancer-related Cognitive Function

Phase 2 Active not recruiting

BreastGastrointestinalGenitourinary

Breast Neoplasms, Prostatic Neoplasms, Colorectal Neoplasms

NCT05571293 2026-05-22

NEST-1

Phase 2 Active not recruiting

26 enrolled 15 charts

Gastrointestinal

Diabetes Mellitus, Insulin-Dependent, 12, Colorectal Neoplasms

NCT06903858 2026-05-22

PICC-3

Phase 2 Recruiting

Gastrointestinal

Turcot syndrome, Colorectal Neoplasms

NCT07604909 2026-05-22

A Phase II Randomized Trial of Serplulimab With Second-Line Chemo/Targeted Therapy for Early Relapse Colorectal Cancer After Adjuvant Chemotherapy

Phase 2 Recruiting

Gastrointestinal

Recurrence, Colorectal Neoplasms

NCT03722680 2026-05-20

RILUZOX-01

Phase 2 Suspended

Gastrointestinal

Colorectal Neoplasms

NCT04787341 2026-05-20

PARERE

Phase 2 Active not recruiting

Gastrointestinal

Colorectal Neoplasms

NCT06959550 2026-05-20

Phase II Study of Anti-PD-1/VEGF Bispecific Antibody Ivonescimab in Patients With Previously Treated Metastatic Colorectal Cancer

Phase 2 Recruiting

Gastrointestinal

Colorectal Neoplasms

NCT07359456 2026-05-19

COLIBRI-GI

Phase 2 Not yet recruiting

Gastrointestinal

Colorectal Neoplasms

NCT07285044 2026-05-18

The Cancer Connected Access and Remote Expertise Beyond Walls Program to Provide In-Home Cancer Treatment and Improve Treatment Satisfaction in Cancer Patients Living in the Florida Panhandle and Surrounding Areas

Phase 2 Recruiting

BreastCNSDermatologicGastrointestinalGenitourinaryGynecologicLymphoidMyeloidPlasma cellThoracic

Amyloidosis, Urinary Bladder Neoplasms, Breast Neoplasms, Carcinoma, Basal Cell, Carcinoma, Renal Cell, Carcinoma, Squamous Cell, Carcinoma, Transitional Cell, Uterine Cervical Neoplasms, Fallopian Tube Neoplasms, Glioblastoma, Carcinoma, Hepatocellular, Hodgkin Disease, Lung Neoplasms, Melanoma, Multiple Myeloma, Myelodysplastic Syndromes, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Colorectal Neoplasms, Carcinoma, Merkel Cell, Endometrial Neoplasms, Lymphoma, Mantle-Cell

NCT06300463 2026-05-15

Platform Study of Immunotherapy Combinations in Colorectal Cancer Liver Metastases

Phase 2 Recruiting

Gastrointestinal

Colorectal Neoplasms

NCT07136077 2026-05-15

A Phase 2 Trial of Fruquintinib and Tislelizumab in ctDNA-defined Minimal Residual Disease in Colorectal Cancer After Completion of Adjuvant Chemotherapy

Phase 2 Recruiting

Gastrointestinal

Colorectal Neoplasms, Neoplasm, Residual

NCT07586813 2026-05-14

N01-A-PICIT-GI

Phase 2 Recruiting

Classical hematologyGastrointestinal

Pathologic Complete Response, Digestive System Neoplasms, Gastrointestinal Neoplasms, Pancreatic Neoplasms, Thrombocytopenia, Colorectal Neoplasms

NCT07446387 2026-05-12

A Clinical Study of Iparomlimab and Tuvonralimab Combined With Bevacizumab and Alternating Triweekly CAPOX/mCAPIRI Regimen as First-line Treatment for Unresectable Advanced Colorectal Cancer

Phase 2 Not yet recruiting

Gastrointestinal

Colorectal Neoplasms

NCT07581912 2026-05-12

FALCO

Phase 2 Recruiting

Gastrointestinal

Colorectal Neoplasms

NCT07576725 2026-05-08

Low Dose, Reduced Frequency Nivolumab for the Treatment of Unresectable or Metastatic Cancer, AFFORD IO Trial

Phase 2 Not yet recruiting

DermatologicGastrointestinalGenitourinaryGynecologicHead & NeckLymphoidSarcomaThoracic

Clear-cell metastatic renal cell carcinoma, Squamous Cell Carcinoma of Head and Neck, Carcinoma, Basal Cell, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Transitional Cell, Uterine Cervical Neoplasms, Hodgkin Disease, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Sarcoma, Kaposi, Colorectal Neoplasms, Carcinoma, Merkel Cell

NCT07448142 2026-05-07

Low-Dose Radiotherapy to Sensitize Pucotenlimab Plus CAPEOX for pMMR Locally Advanced Rectal Cancer

Phase 2 Recruiting

Gastrointestinal

Colorectal Neoplasms

NCT06205836 2026-05-06

Cemiplimab With or Without Fianlimab to Treat Older Patients With Localized or Locally Advanced MSI-H Colorectal Cancer

Phase 2 Recruiting

Gastrointestinal

Adenocarcinoma, Carcinoma, Colorectal Neoplasms

NCT06258525 2026-05-06

SAMe in Prevention of Oxaliplatin-associated Liver Injury

Phase 2 Not yet recruiting

Classical hematologyGastrointestinal

Hepatic Veno-Occlusive Disease, Colorectal Neoplasms, Chemical and Drug Induced Liver Injury

NCT06728072 2026-05-06

Addition of Antibiotics to Upfront Treatment Regimen for Colorectal Cancer

Phase 2 Recruiting

Gastrointestinal

Colorectal Neoplasms

NCT07281768 2026-05-06

Capecitabine/Oxaliplatin Chemotherapy and Cemiplimab With or Without Fianlimab or REGN7075 in Locally Advanced Rectal Cancer

Phase 2 Not yet recruiting

Gastrointestinal

Adenocarcinoma, Carcinoma, Rectal Neoplasms, Colorectal Neoplasms

NCT07570914 2026-05-06

Hepatic Arterial Infusion of Liposomal Irinotecan Plus Oxaliplatin and Capecitabine as Adjuvant Therapy for Colorectal Cancer Liver Metastases

Phase 2 Not yet recruiting

Gastrointestinal

Colorectal Neoplasms

NCT07503756 2026-05-05

JS212 Combination Therapies in Metastatic Colorectal Cancer

Phase 2 Recruiting

Gastrointestinal

Colorectal Neoplasms

NCT07562490 2026-05-01

CLEAR-04

Phase 2 Recruiting

Gastrointestinal

Colorectal Neoplasms

NCT07562503 2026-05-01

CLEAR-03

Phase 2 Recruiting

Gastrointestinal

Colorectal Neoplasms

NCT07562659 2026-05-01

CLEAR-01

Phase 2 Recruiting

Gastrointestinal

Colorectal Neoplasms

NCT07562711 2026-05-01

CLEAR-02

Phase 2 Recruiting

Gastrointestinal

Colorectal Neoplasms

NCT05776381 2026-04-30

The Impact of a Patient Decision Aid on Treatment Choices for Patients With an Unexpected Malignant Colorectal Polyp

Phase 2 Not yet recruiting

Gastrointestinal

Colonic Polyps, Colorectal Neoplasms

NCT07024537 2026-04-30

HAIC，CRLM

Phase 2 Completed

Gastrointestinal

Colorectal Neoplasms

NCT07559760 2026-04-30

New Second-Line Combo Therapy for MSS Metastatic Colorectal Cancer

Phase 2 Recruiting

Gastrointestinal

Colorectal Neoplasms

NCT06356584 2026-04-28

Fruquintinib Combined With Sintilimab ± Radiotherapy for Third-line Treatment of Colorectal Cancer With Liver Metastases

Phase 2 Recruiting

Gastrointestinal

Colorectal Neoplasms

NCT06002789 2026-04-27

Safety and Efficacy of PD-1 ± mFOLFOX6 Neoadjuvant Therapy in Local Advanced sMPCC

Phase 2 Recruiting

Gastrointestinal

Colorectal Neoplasms

NCT06428487 2026-04-27

Neoadjuvant Prolgolimab Monotherapy in Locally Advanced MMR-deficient Colorectal Cancer

Phase 2 Completed

Gastrointestinal

Colorectal Neoplasms, Microsatellite Instability

NCT07542262 2026-04-24

NIVO402025

Phase 2 Enrolling by invitation

Gastrointestinal

Stomach Neoplasms, Colorectal Neoplasms

NCT07550088 2026-04-24

BAL/BOT/agenT-797 in pMMR CRC With Liver Metastases

Phase 2 Not yet recruiting

Gastrointestinal

Colorectal Neoplasms

NCT06475352 2026-04-23

FUDOSE

Phase 2 Recruiting

Gastrointestinal

Gastrointestinal Neoplasms, Neoplasm Metastasis, Neoplasms, Recurrence, Colorectal Neoplasms

NCT03981146 2026-04-22

ANICCA

Phase 2 Completed

35 enrolled 15 charts

Gastrointestinal

Colorectal Neoplasms

NCT07405476 2026-04-17

Zanidatamab Before Surgery for the Treatment of HER2 Positive Colon and Rectal Cancer in Patients Planned for Curative Intent Treatment

Phase 2 Recruiting

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT07523763 2026-04-17

NIVO1002024

Phase 2 Active not recruiting

Gastrointestinal

Colorectal Neoplasms

NCT07535632 2026-04-17

BEST

Phase 2 Not yet recruiting

Gastrointestinal

Colorectal Neoplasms

NCT04355156 2026-04-16

AXMUS-C

Phase 2 Completed

52 enrolled 12 charts

Gastrointestinal

Colorectal Neoplasms

NCT06617858 2026-04-16

Trial of AMB-05X for Patients With ctDNA(+) Colorectal Cancer After Curative-intent Treatment

Phase 2 Recruiting

Gastrointestinal

Colorectal Neoplasms

NCT07042685 2026-04-09

Trial of 5-Fluorouracil (5FU)-Based Therapy in Combination With Fruquintinib in Patients With Locally Advanced Unresectable or Metastatic Colorectal Cancer

Phase 2 Recruiting

Gastrointestinal

Neoplasm Metastasis, Colorectal Neoplasms

NCT07506109 2026-04-07

A Phase II Study of Sintilimab Combined With Ipilimumab N01, Cetuximab and Dabrafenib in Patients With Microsatellite-Stable, BRAF V600E-Mutated Metastatic Colorectal Cancer

Phase 2 Recruiting

Gastrointestinal

Spinocerebellar Degenerations, Colorectal Neoplasms

NCT07515820 2026-04-07

SHR-3821 in Advanced Colorectal Cancer: an Exploratory Study

Phase 2 Not yet recruiting

Gastrointestinal

Colorectal Neoplasms

NCT07515963 2026-04-07

FULIRI Plus Targeted Therapy for First-line Conversion Therapy of Colorectal Cancer Liver Metastases.

Phase 2 Not yet recruiting

Gastrointestinal

Colonic Neoplasms, Colorectal Neoplasms

NCT04245865 2026-04-03

Toco-CoR

Phase 2 Active not recruiting

Gastrointestinal

Colorectal Neoplasms

NCT03796884 2026-04-02

Linaclotide in Treating Patients With Stages 0-3 Colorectal Cancer

Phase 2 Active not recruiting

Gastrointestinal

Colorectal Neoplasms

NCT05854498 2026-04-02

Liposomal Irinotecan With TAS102 and Bevacizumab for Patients With Metastatic Colorectal Cancer

Phase 2 Recruiting

Gastrointestinal

Colorectal Neoplasms