Clinical Trials Browser

Amyloidosis, Urinary Bladder Neoplasms, Breast Neoplasms, Carcinoma, Basal Cell, Carcinoma, Renal Cell, Carcinoma, Squamous Cell, Carcinoma, Transitional Cell, Uterine Cervical Neoplasms, Fallopian Tube Neoplasms, Glioblastoma, Carcinoma, Hepatocellular, Hodgkin Disease, Lung Neoplasms, Melanoma, Multiple Myeloma, Myelodysplastic Syndromes, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Colorectal Neoplasms, Carcinoma, Merkel Cell, Endometrial Neoplasms, Lymphoma, Mantle-Cell

NCT06300463 2026-05-15

Platform Study of Immunotherapy Combinations in Colorectal Cancer Liver Metastases

Phase 2 Recruiting

24 enrolled

Gastrointestinal

Colorectal Neoplasms

NCT07136077 2026-05-15

A Phase 2 Trial of Fruquintinib and Tislelizumab in ctDNA-defined Minimal Residual Disease in Colorectal Cancer After Completion of Adjuvant Chemotherapy

Phase 2 Recruiting

20 enrolled

Gastrointestinal

Colorectal Neoplasms, Neoplasm, Residual

NCT07586813 2026-05-14

N01-A-PICIT-GI

Phase 2 Recruiting

220 enrolled

Classical hematologyGastrointestinal

Pathologic Complete Response, Digestive System Neoplasms, Gastrointestinal Neoplasms, Pancreatic Neoplasms, Thrombocytopenia, Colorectal Neoplasms

NCT06557733 2026-05-13

An Investigational Drug (TPST-1495) in Patients With Familial Adenomatous Polyposis

Phase 2 Recruiting

38 enrolled

Gastrointestinal

Adenomatous Polyposis Coli, Colorectal Neoplasms

NCT07581912 2026-05-12

FALCO

Phase 2 Recruiting

40 enrolled

Gastrointestinal

Colorectal Neoplasms

NCT06792695 2026-05-11

CANTOR

Phase 2 Recruiting

120 enrolled

Gastrointestinal

Neoplasm Metastasis, Colorectal Neoplasms

NCT06937177 2026-05-11

Safely Optimizing Body Weight With TCMCB07 in Patients With Newly Diagnosed Colorectal Cancer Undergoing Chemotherapy

Phase 2 Recruiting

120 enrolled

Gastrointestinal

Cachexia, Colorectal Neoplasms, Weight Loss

NCT06760819 2026-05-07

panSOHO

Phase 2 Recruiting

111 enrolled

BreastGastrointestinalGenitourinaryGynecologicSarcoma

Biliary Tract Neoplasms, Urinary Bladder Neoplasms, Breast Neoplasms, Uterine Cervical Neoplasms, Esophageal Neoplasms, Gallbladder Neoplasms, Gastrointestinal Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Sarcoma, Stomach Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms, Gastrointestinal Stromal Tumors

NCT07448142 2026-05-07

Low-Dose Radiotherapy to Sensitize Pucotenlimab Plus CAPEOX for pMMR Locally Advanced Rectal Cancer

Phase 2 Recruiting

50 enrolled

Gastrointestinal

Colorectal Neoplasms

NCT06205836 2026-05-06

Cemiplimab With or Without Fianlimab to Treat Older Patients With Localized or Locally Advanced MSI-H Colorectal Cancer

Phase 2 Recruiting

44 enrolled

Gastrointestinal

Adenocarcinoma, Carcinoma, Colorectal Neoplasms

NCT06728072 2026-05-06

Addition of Antibiotics to Upfront Treatment Regimen for Colorectal Cancer

Phase 2 Recruiting

97 enrolled

Gastrointestinal

Colorectal Neoplasms

NCT07503756 2026-05-05

JS212 Combination Therapies in Metastatic Colorectal Cancer

Phase 2 Recruiting

80 enrolled

Gastrointestinal

Colorectal Neoplasms

NCT05286814 2026-05-04

PDS01ADC in Combination With Hepatic Artery Infusion Pump (HAIP) and Systemic Therapy for Subjects With Metastatic Colorectal Cancer, Intrahepatic Cholangiocarcinoma, or Metastatic Adrenocortical Carcinoma

Phase 2 Recruiting

70 enrolled

EndocrineGastrointestinal

Cirrhosis, Familial, with Pulmonary Hypertension, Adrenal Cortex Neoplasms, Adrenal Gland Neoplasms, Bile Duct Neoplasms, Colorectal Neoplasms, Adrenocortical Carcinoma, Cholangiocarcinoma

NCT07562490 2026-05-01

CLEAR-04

Phase 2 Recruiting

100 enrolled

Gastrointestinal

Colorectal Neoplasms

NCT07562503 2026-05-01

CLEAR-03

Phase 2 Recruiting

340 enrolled

Gastrointestinal

Colorectal Neoplasms

NCT07562659 2026-05-01

CLEAR-01

Phase 2 Recruiting

80 enrolled

Gastrointestinal

Colorectal Neoplasms

NCT07562711 2026-05-01

CLEAR-02

Phase 2 Recruiting

340 enrolled

Gastrointestinal

Colorectal Neoplasms

NCT07559760 2026-04-30

New Second-Line Combo Therapy for MSS Metastatic Colorectal Cancer

Phase 2 Recruiting

30 enrolled

Gastrointestinal

Colorectal Neoplasms

NCT06356584 2026-04-28

Fruquintinib Combined With Sintilimab ± Radiotherapy for Third-line Treatment of Colorectal Cancer With Liver Metastases

Phase 2 Recruiting

62 enrolled

Gastrointestinal

Colorectal Neoplasms

NCT06589830 2026-04-28

TL938 and Trastuzumab for Patients With HER2-positive Metastatic Colorectal Cancer

Phase 2 Recruiting

80 enrolled

Gastrointestinal

Neoplasms, Colorectal Neoplasms

NCT06002789 2026-04-27

Safety and Efficacy of PD-1 ± mFOLFOX6 Neoadjuvant Therapy in Local Advanced sMPCC

Phase 2 Recruiting

17 enrolled

Gastrointestinal

Colorectal Neoplasms

NCT06475352 2026-04-23

FUDOSE

Phase 2 Recruiting

400 enrolled

Gastrointestinal

Gastrointestinal Neoplasms, Neoplasm Metastasis, Neoplasms, Recurrence, Colorectal Neoplasms

NCT07405476 2026-04-17

Zanidatamab Before Surgery for the Treatment of HER2 Positive Colon and Rectal Cancer in Patients Planned for Curative Intent Treatment

Phase 2 Recruiting

38 enrolled

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT04701476 2026-04-16

TATE and Pembrolizumab (MK3475) in mCRC and NSCLC

Phase 2 Recruiting

110 enrolled

GastrointestinalThoracic

Lung Neoplasms, Colorectal Neoplasms

NCT06617858 2026-04-16

Trial of AMB-05X for Patients With ctDNA(+) Colorectal Cancer After Curative-intent Treatment

Phase 2 Recruiting

15 enrolled

Gastrointestinal

Colorectal Neoplasms

NCT06695845 2026-04-09

A Phase 2 Study of Zanidatamab in Patients With HER2-expressing Tumors

Phase 2 Recruiting

200 enrolled

BreastGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Transitional Cell, Esophageal Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Salivary Gland Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms

NCT07042685 2026-04-09

Trial of 5-Fluorouracil (5FU)-Based Therapy in Combination With Fruquintinib in Patients With Locally Advanced Unresectable or Metastatic Colorectal Cancer

Phase 2 Recruiting

50 enrolled

Gastrointestinal

Neoplasm Metastasis, Colorectal Neoplasms

NCT07506109 2026-04-07

A Phase II Study of Sintilimab Combined With Ipilimumab N01, Cetuximab and Dabrafenib in Patients With Microsatellite-Stable, BRAF V600E-Mutated Metastatic Colorectal Cancer

Phase 2 Recruiting

49 enrolled

Gastrointestinal

Spinocerebellar Degenerations, Colorectal Neoplasms

NCT05854498 2026-04-02

Liposomal Irinotecan With TAS102 and Bevacizumab for Patients With Metastatic Colorectal Cancer

Phase 2 Recruiting

50 enrolled

Gastrointestinal

Colorectal Neoplasms

NCT04779554 2026-04-01

Flat Dose vs. Weight-based IP Chemotherapy for CRS/HIPEC

Phase 2 Recruiting

100 enrolled

GastrointestinalGynecologic

Appendiceal Neoplasms, Peritoneal Neoplasms, Pseudomyxoma Peritonei, Colorectal Neoplasms

NCT06553885 2026-04-01

Ph II Study of Enfortumab Vedotin in Patients With Advanced or Metastatic CRC or HCC

Phase 2 Recruiting

40 enrolled

Gastrointestinal

Carcinoma, Hepatocellular, Colorectal Neoplasms

NCT07033026 2026-04-01

An Evaluation of NGM120 in a Randomized, Double-blind, Placebo-controlled Study in Participants With Colorectal Cancer Who Have Cancer Cachexia.

Phase 2 Recruiting

136 enrolled

Gastrointestinal

Colorectal Neoplasms

NCT06634875 2026-03-31

Isunakinra Alone and in Combination With Pembrolizumab in Patients With Colorectal Cancer (MSS)

Phase 2 Recruiting

20 enrolled

Gastrointestinal

Neoplasm Metastasis, Colorectal Neoplasms

NCT03667170 2026-03-25

KN035 for dMMR/MSI-H Advanced Solid Tumors

Phase 2 Recruiting

200 enrolled

Gastrointestinal

Colorectal Neoplasms

NCT06850103 2026-03-25

SCRT-CAPEOX-Serplulimab for MSS/pMMR Rectal Cancer With Oligometastases

Phase 2 Recruiting

51 enrolled

Gastrointestinal

Colorectal Neoplasms

NCT06692959 2026-03-23

Neo-POLEM

Phase 2 Recruiting

44 enrolled

Gastrointestinal

Colorectal Neoplasms

NCT05489211 2026-03-19

Study of Dato-DXd as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid Tumours (TROPION-PanTumor03)

Phase 2 Recruiting

454 enrolled

GastrointestinalGynecologic

Biliary Tract Neoplasms, Ovarian Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms

NCT07011576 2026-03-18

FRUITFUL

Phase 2 Recruiting

60 enrolled

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT07071714 2026-03-18

A Phase II Study of SHR-8068 Injection in Combination With Anti-tumor Therapies in Colorectal Cancer

Phase 2 Recruiting

200 enrolled

Gastrointestinal

Colorectal Neoplasms

Clinical Trials

AndroMETa-CRC

Hydroxychloroquine in Combination With Encorafenib and Cetuximab or Panitumumab in the Treatment of Metastatic BRAF-mutated Colorectal Cancer Refractory

Immunotherapy Using Tumor Infiltrating Lymphocytes for Patients With Metastatic Cancer

PICC-3

A Study to Assess Adverse Events and Change in Disease Activity in Adult Participants Receiving Intravenously Infused Telisotuzumab Adizutecan Alone or With Standard of Care in Participants With Post Adjuvant Circulating Tumor DNA Positive Colorectal Cancer and No Radiographic Evidence of Disease

A Study to Test DSP107 in Combination With Atezolizumab in Comparison With Fruquintinib as a New Treatment for Colorectal Cancer.

A Phase II Randomized Trial of Serplulimab With Second-Line Chemo/Targeted Therapy for Early Relapse Colorectal Cancer After Adjuvant Chemotherapy

Phase II Study of Anti-PD-1/VEGF Bispecific Antibody Ivonescimab in Patients With Previously Treated Metastatic Colorectal Cancer

VISTA-1

A Study to Evaluate the Safety and Efficacy of Two Dose Levels of ONO-4578 With Opdivo®, in Combination With mFOLFOX6 and Bevacizumab Versus Standard of Care in Participants With Non-MSI-H/dMMR, PD-L1 Positive Advanced Colorectal Cancer

The Cancer Connected Access and Remote Expertise Beyond Walls Program to Provide In-Home Cancer Treatment and Improve Treatment Satisfaction in Cancer Patients Living in the Florida Panhandle and Surrounding Areas

Platform Study of Immunotherapy Combinations in Colorectal Cancer Liver Metastases

A Phase 2 Trial of Fruquintinib and Tislelizumab in ctDNA-defined Minimal Residual Disease in Colorectal Cancer After Completion of Adjuvant Chemotherapy

N01-A-PICIT-GI

An Investigational Drug (TPST-1495) in Patients With Familial Adenomatous Polyposis

FALCO

CANTOR

Safely Optimizing Body Weight With TCMCB07 in Patients With Newly Diagnosed Colorectal Cancer Undergoing Chemotherapy

panSOHO

Low-Dose Radiotherapy to Sensitize Pucotenlimab Plus CAPEOX for pMMR Locally Advanced Rectal Cancer

Cemiplimab With or Without Fianlimab to Treat Older Patients With Localized or Locally Advanced MSI-H Colorectal Cancer

Addition of Antibiotics to Upfront Treatment Regimen for Colorectal Cancer

JS212 Combination Therapies in Metastatic Colorectal Cancer

PDS01ADC in Combination With Hepatic Artery Infusion Pump (HAIP) and Systemic Therapy for Subjects With Metastatic Colorectal Cancer, Intrahepatic Cholangiocarcinoma, or Metastatic Adrenocortical Carcinoma

CLEAR-04

CLEAR-03

CLEAR-01

CLEAR-02

New Second-Line Combo Therapy for MSS Metastatic Colorectal Cancer

Fruquintinib Combined With Sintilimab ± Radiotherapy for Third-line Treatment of Colorectal Cancer With Liver Metastases

TL938 and Trastuzumab for Patients With HER2-positive Metastatic Colorectal Cancer

Safety and Efficacy of PD-1 ± mFOLFOX6 Neoadjuvant Therapy in Local Advanced sMPCC

FUDOSE

Zanidatamab Before Surgery for the Treatment of HER2 Positive Colon and Rectal Cancer in Patients Planned for Curative Intent Treatment

TATE and Pembrolizumab (MK3475) in mCRC and NSCLC

Trial of AMB-05X for Patients With ctDNA(+) Colorectal Cancer After Curative-intent Treatment

A Phase 2 Study of Zanidatamab in Patients With HER2-expressing Tumors

Trial of 5-Fluorouracil (5FU)-Based Therapy in Combination With Fruquintinib in Patients With Locally Advanced Unresectable or Metastatic Colorectal Cancer

A Phase II Study of Sintilimab Combined With Ipilimumab N01, Cetuximab and Dabrafenib in Patients With Microsatellite-Stable, BRAF V600E-Mutated Metastatic Colorectal Cancer

Liposomal Irinotecan With TAS102 and Bevacizumab for Patients With Metastatic Colorectal Cancer

Flat Dose vs. Weight-based IP Chemotherapy for CRS/HIPEC

Ph II Study of Enfortumab Vedotin in Patients With Advanced or Metastatic CRC or HCC

An Evaluation of NGM120 in a Randomized, Double-blind, Placebo-controlled Study in Participants With Colorectal Cancer Who Have Cancer Cachexia.

Isunakinra Alone and in Combination With Pembrolizumab in Patients With Colorectal Cancer (MSS)

KN035 for dMMR/MSI-H Advanced Solid Tumors

SCRT-CAPEOX-Serplulimab for MSS/pMMR Rectal Cancer With Oligometastases

Neo-POLEM

Study of Dato-DXd as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid Tumours (TROPION-PanTumor03)

FRUITFUL

A Phase II Study of SHR-8068 Injection in Combination With Anti-tumor Therapies in Colorectal Cancer