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Phase

Phase 2 4Phase 1 2Phase 2/3 1Phase 1/2 1

Status

Completed 1

Sponsor Class

NIH 1

Study Type

Interventional 1

Sponsor

Cancer Type

Other hematologic neoplasm 1Myeloid 1Classical hematology 1

Conditions

Leukemia, Myeloid, Acute 9Myelodysplastic Syndromes 4Leukemia 2Anemia, Refractory, with Excess of Blasts 2Lymphoma, T-Cell, Peripheral 1Lymphoma, Large B-Cell, Diffuse 1Lymphoma, B-Cell, Marginal Zone 1Leukemia, Myelomonocytic, Chronic 1Leukemia, Myelomonocytic, Acute 1Leukemia, Monocytic, Acute 1Leukemia, Megakaryoblastic, Acute 1Leukemia, Erythroblastic, Acute 1Leukemia, Eosinophilic, Acute 1Leukemia, Basophilic, Acute 1Hematologic Neoplasms 1Hematologic Diseases 1GATA2 Deficiency 1Frailty 1Congenital Abnormalities 1

Interventions

Busulfan 3fludarabine phosphate 2Whole-Body Irradiation 2Melphalan 2Gemtuzumab 2Etoposide 2Cyclophosphamide 2tipifarnib 1sargramostim 1Thiotepa 1Peripheral Blood Stem Cell Transplantation 1Immunologic Techniques 1Hematopoietic Stem Cell Transplantation 1Granulocyte Colony-Stimulating Factor 1Gene Expression Profiling 1Dexamethasone 1Daunorubicin 1DNA Methylation 1Cytogenetic Analysis 1Cytarabine 1Clofarabine 1Carboplatin 1Calcium Dobesilate 1Bone Marrow Transplantation 1Azacitidine 1Arsenic Trioxide 1Antilymphocyte Serum 1Alemtuzumab 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Phase 2/3 × Congenital Abnormalities × Azacitidine × Clear all
NCT00454480 2013-08-26

Combination Chemotherapy With or Without Gemtuzumab Ozogamicin or Tipifarnib in Treating Patients With Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndromes

National Cancer Institute (NCI)

Phase 2/3 Completed
2,000 enrolled
Classical hematologyMyeloidOther hematologic neoplasm

Congenital Abnormalities, Anemia, Refractory, with Excess of Blasts, Leukemia, Erythroblastic, Acute, Leukemia, Leukemia, Megakaryoblastic, Acute, Leukemia, Monocytic, Acute, Myelodysplastic Syndromes, Leukemia, Myeloid, Acute, Leukemia, Basophilic, Acute, Leukemia, Eosinophilic, Acute, Leukemia, Myelomonocytic, Acute

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