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Phase

Phase 2 6Phase 1 2Phase NA 1Phase 2/3 1Phase 1/2 1

Status

Completed 1

Sponsor Class

OTHER 1

Study Type

Interventional 1

Sponsor

Cancer Type

Other hematologic neoplasm 1Myeloid 1Lymphoid 1

Conditions

Myelodysplastic Syndromes 5Leukemia 5Precursor Cell Lymphoblastic Leukemia-Lymphoma 4Leukemia, Myeloid, Acute 4Breast Neoplasms 4Lymphoma, Non-Hodgkin 3Lymphoma 3Ovarian Neoplasms 2Leukemia, Myelomonocytic, Juvenile 2Leukemia, Myeloid, Accelerated Phase 2Leukemia, Myelogenous, Chronic, BCR-ABL Positive 2Hematologic Neoplasms 2Carcinoma, Ovarian Epithelial 2Blast Crisis 2Shwachman-Diamond Syndrome 1Primary Immunodeficiency Diseases 1Neutropenia, Severe Congenital, Autosomal Recessive 3 1Neuroblastoma 1Neoplasms, Plasma Cell 1Macrophage Activation Syndrome 1Lymphohistiocytosis, Hemophagocytic 1Leukemia, Myeloid, Chronic-Phase 1Leukemia, Lymphocytic, Chronic, B-Cell 1Leukemia, Biphenotypic, Acute 1Immunologic Deficiency Syndromes 1Hodgkin Disease 1Histiocytosis, Langerhans-Cell 1Histiocytosis 1High Risk Myeloid Malignancies 1Hemoglobinopathies 1

Interventions

Cytarabine 12Peripheral Blood Stem Cell Transplantation 10fludarabine phosphate 7Cyclosporine 7Mycophenolic Acid 6Busulfan 6Methotrexate 5Melphalan 4Idarubicin 4Filgrastim 4Etoposide 4Clofarabine 4aldesleukin 3Whole-Body Irradiation 3Tacrolimus 3Radiotherapy 3Mitoxantrone 3Flow Cytometry 3Daunorubicin 3Cyclophosphamide 3Antilymphocyte Serum 3Transplantation 2Radiotherapy, Intensity-Modulated 2Interleukin-2 2Granulocyte Colony-Stimulating Factor 2Cytogenetic Analysis 2Bortezomib 2Alemtuzumab 2tipifarnib 1liposomal doxorubicin 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Phase 1/2 × Congenital Abnormalities × Thiotepa × Clear all
NCT00423514 2022-12-27

Clofarabine, Melphalan, and Thiotepa Followed By a Donor Stem Cell Transplant in Treating Patients With High-Risk and/or Advanced Hematologic Cancer or Other Disease

Memorial Sloan Kettering Cancer Center

Phase 1/2 Completed
38 enrolled 12 charts
LymphoidMyeloidOther hematologic neoplasm

Congenital Abnormalities, Blast Crisis, Graft vs Host Disease, Leukemia, Myelodysplastic Syndromes, Leukemia, Biphenotypic, Acute, Leukemia, Myeloid, Accelerated Phase, Leukemia, Myeloid, Chronic-Phase, Leukemia, Myeloid, Acute, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Leukemia, Myelomonocytic, Juvenile

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