Announcements Trials
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Phase

Phase 1 2Phase 1/2 1

Status

Active not recruiting 2Completed 1

Sponsor Class

OTHER 3

Study Type

Interventional 3

Sponsor

Cancer Type

Lymphoid 2Other hematologic neoplasm 1CNS 1

Conditions

Leukemia, Myeloid, Acute 196Myelodysplastic Syndromes 128Precursor Cell Lymphoblastic Leukemia-Lymphoma 123Leukemia, Lymphocytic, Chronic, B-Cell 102Leukemia 102Lymphoma 86Multiple Myeloma 81Lymphoma, Non-Hodgkin 80Hematologic Neoplasms 65Leukemia, Myelogenous, Chronic, BCR-ABL Positive 62Hodgkin Disease 62Recurrence 52Lymphoma, B-Cell 40Lymphoma, Mantle-Cell 39Myeloproliferative Disorders 36Lymphoma, Follicular 35Melanoma 34Lymphoma, Large B-Cell, Diffuse 31Burkitt Lymphoma 31Graft vs Host Disease 28Neoplasms, Plasma Cell 24Primary Myelofibrosis 23Ovarian Neoplasms 23Lymphoma, B-Cell, Marginal Zone 23Anemia, Refractory, with Excess of Blasts 21Leukemia, Myelomonocytic, Chronic 20Leukemia, Biphenotypic, Acute 17Lymphoma, T-Cell 16Neuroblastoma 15Neoplasms 14

Interventions

siltuximab 4fludarabine 3Cyclophosphamide 3fludarabine phosphate 2Interleukin 1 Receptor Antagonist Protein 2AP 1903 reagent 2tocilizumab 1talquetamab 1axicabtagene ciloleucel 1Neuropsychological Tests 1Metoprolol 1Magnetic Resonance Spectroscopy 1Leukapheresis 1Infliximab 1Etanercept 1Dexamethasone 1Contrast Media 1Calcium Dobesilate 1Blood Specimen Collection 1Bendamustine Hydrochloride 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
OTHER × Cytokine Release Syndrome × fludarabine × Clear all
NCT03696784 2025-12-08

Anti-CD19 CAR-T Cells With Inducible Caspase 9 Safety Switch for B-cell Lymphoma

UNC Lineberger Comprehensive Cancer Center

Phase 1 Active not recruiting
19 enrolled
Lymphoid

Cytokine Release Syndrome, Immune System Diseases, Immunoproliferative Disorders, Lymphatic Diseases, Lymphoma, Lymphoma, B-Cell, Neurotoxicity Syndromes

NCT03016377 2025-10-27

Administration of Autologous CAR-T CD19 Antigen With Inducible Safety Switch in Patients With Relapsed/Refractory ALL

UNC Lineberger Comprehensive Cancer Center

Phase 1/2 Active not recruiting
17 enrolled
LymphoidOther hematologic neoplasm

Cytokine Release Syndrome, Immune System Diseases, Immunoproliferative Disorders, Leukemia, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT02761915 2021-08-17

A Phase I Trial of Anti-GD2 T-cells (1RG-CART)

Cancer Research UK

Phase 1 Completed
17 enrolled 17 charts
CNS

Cytokine Release Syndrome, Neuroblastoma, Recurrence

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