Announcements Trials
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Phase

Phase NA 5Phase 4 1

Status

Not yet recruiting 3Completed 2Recruiting 1

Sponsor Class

OTHER 6

Study Type

Interventional 6

Sponsor

Cancer Type

Breast 3Gynecologic 1

Conditions

Depression 6Breast Neoplasms 4Anxiety Disorders 4Pain, Postoperative 3Pain 3Carcinoma, Hepatocellular 2Spinal Cord Neoplasms 1Sleep Initiation and Maintenance Disorders 1Sleep Deprivation 1Ovarian Neoplasms 1Breast Cancer Surgery 1

Interventions

Therapeutics 29Psychiatric Rehabilitation 20Cognitive Behavioral Therapy 12Early Intervention, Educational 10Psilocybin 9Ketamine 9Methods 8Saline Solution 7Yoga 6Surveys and Questionnaires 6Mindfulness-Based Cognitive Therapy 6Esketamine 6Counseling 6Psychosocial Intervention 5Mindfulness 5Methylphenidate 5Educational Status 5Behavior Therapy 5Acupuncture Therapy 5Interviews as Topic 4Exercise Therapy 4Exercise 4Escitalopram 4Control Groups 4Caregivers 4Psychotherapy 3Palliative Care 3Niacin 3Mindfulness-Based Stress Reduction 3Melatonin 3

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

6 trials
RecentStart dateEnrollment
Interventional × Depression × Esketamine × Clear all
NCT06624878 2026-02-27

Esketamine for Prevention of Depression After Cytoreductive Surgery in Ovarian Cancer

Zhejiang Cancer Hospital

Phase NA Completed
568 enrolled
Gynecologic

Depression, Ovarian Neoplasms

NCT07374198 2026-01-28

Effect of Continuous Intraoperative Esketamine Infusion on Perioperative Negative Emotions in Breast Cancer Surgery Patients With Mild-to-Severe Depression

Chinese PLA General Hospital

Phase NA Not yet recruiting
142 enrolled
Breast

Anxiety Disorders, Breast Neoplasms, Depression

NCT07374211 2026-01-28

Effect of Esketamine on Perioperative Negative Emotions in Breast Cancer Surgery Patients With Severe Depression

Chinese PLA General Hospital

Phase NA Not yet recruiting
242 enrolled
Breast

Anxiety Disorders, Breast Neoplasms, Depression

NCT07367542 2026-01-27

Effect of Esketamine on Perioperative Negative Emotions in Patients Undergoing Breast Cancer Surgery

Chinese PLA General Hospital

Phase NA Not yet recruiting
218 enrolled
Breast

Anxiety Disorders, Breast Neoplasms, Depression

NCT04303325 2024-07-22

ESPOD-BI

China Medical University, China

Phase 4 Recruiting
72 enrolled

Depression, Sleep Deprivation

NCT04850937 2022-07-28

Effect of Low-dose Esketamine on Postoperative Depression in Patients With Breast Cancer

Yangzhou University

Phase NA Completed
90 enrolled

Depression, Pain

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