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Phase

Phase EARLY_PHASE1 1Phase 2 1Phase 1/2 1

Status

Completed 1

Sponsor Class

OTHER 1

Study Type

Interventional 1

Sponsor

Cancer Type

Sarcoma 1

Conditions

Colorectal Neoplasms 38Pancreatic Neoplasms 16Colonic Neoplasms 12Rectal Neoplasms 11Stomach Neoplasms 9Neoplasms 9Neuroblastoma 8Small Cell Lung Carcinoma 7Rhabdomyosarcoma 7Neoplasm Metastasis 7Glioblastoma 7Sarcoma, Ewing 6Gastrointestinal Neoplasms 6Central Nervous System Neoplasms 6Carcinoma, Non-Small-Cell Lung 6Glioma 5Sarcoma 4Brain Neoplasms 4Medulloblastoma 3Intestinal Neoplasms 3Gliosarcoma 3Gastrointestinal Diseases 3Esophageal Neoplasms 3Digestive System Neoplasms 3Digestive System Diseases 3Astrocytoma 3Advanced Solid Tumors 3Recurrence 2Rectal Diseases 2Parkinson Disease 4, Autosomal Dominant Lewy Body 2

Interventions

Cyclophosphamide 2seclidemstat 1prexasertib 1pegylated granulocyte colony-stimulating factor 1pegfilgrastim 1Zoledronic Acid 1Vinorelbine 1Vincristine 1Topotecan 1Temozolomide 1Ramucirumab 1PM 01183 1Irinotecan 1HhAntag691 1Granulocyte Colony-Stimulating Factor 1Filgrastim 12,2-dimethyl-N-(6-oxo-6,7-dihydro-5H-dibenzo(b,d)azepin-7-yl)-N'-(2,2,3,3,3-pentafluoropropyl)malonamide 1

Date Range

30 days90 days1 yearAll

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Clinical Trials

1 trials
RecentStart dateEnrollment
Phase 1/2 × Desmoplastic Small Round Cell Tumor × Irinotecan × Clear all
NCT04095221 2025-02-20

A Study of the Drugs Prexasertib, Irinotecan, and Temozolomide in People With Desmoplastic Small Round Cell Tumor and Rhabdomyosarcoma

Memorial Sloan Kettering Cancer Center

Phase 1/2 Completed
21 enrolled
Sarcoma

Rhabdomyosarcoma, Desmoplastic Small Round Cell Tumor

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