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Phase

Phase EARLY_PHASE1 1Phase 2 1Phase 1/2 1

Status

Active not recruiting 2Recruiting 1

Sponsor Class

OTHER 3

Study Type

Interventional 3

Sponsor

Cancer Type

Sarcoma 2

Conditions

Glioblastoma 393Brain Neoplasms 162Glioma 156Gliosarcoma 130Astrocytoma 111Central Nervous System Neoplasms 109Melanoma 75Oligodendroglioma 73Neuroblastoma 44Neoplasms 33Medulloblastoma 33Neoplasm Metastasis 29Recurrence 28Ependymoma 25Sarcoma 23Sarcoma, Ewing 22Rhabdomyosarcoma 18Small Cell Lung Carcinoma 16Lymphoma 16Carcinoma, Non-Small-Cell Lung 16Diffuse Intrinsic Pontine Glioma 15Lung Neoplasms 14Breast Neoplasms 14Ovarian Neoplasms 13Neuroendocrine Tumors 13Choroid Plexus Neoplasms 13Optic Nerve Glioma 11Neuroectodermal Tumors, Primitive 11Spinal Cord Neoplasms 10Rhabdoid Tumor 10

Interventions

Cyclophosphamide 10Doxorubicin 9Vincristine 7Etoposide 7Ifosfamide 6Filgrastim 5Radiotherapy 4fludarabine phosphate 3Topotecan 3Thiotepa 3Temozolomide 3Peripheral Blood Stem Cell Transplantation 3Melphalan 3Irinotecan 3Cisplatin 3Carboplatin 3Brachytherapy 3seclidemstat 2Tacrolimus 2PM 01183 2Neoadjuvant Therapy 2Injections 2Hyperthermic Intraperitoneal Chemotherapy 2Granulocyte Colony-Stimulating Factor 2Epirubicin 2Dactinomycin 2Cytoreduction Surgical Procedures 2Cyclosporine 2Chemotherapy, Adjuvant 2thymoglobulin 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Interventional × Desmoplastic Small Round Cell Tumor × Temozolomide × Clear all
NCT01946529 2026-02-23

Therapeutic Trial for Patients With Ewing Sarcoma Family of Tumor and Desmoplastic Small Round Cell Tumors

St. Jude Children's Research Hospital

Phase 2 Active not recruiting
24 enrolled 11 charts

Neuroectodermal Tumors, Primitive, Peripheral, Desmoplastic Small Round Cell Tumor

NCT06709495 2026-02-19

Phase 1/2 Trial to Evaluate the Safety and Efficacy of PEEL-224 in Combination With Vincristine and Temozolomide in Adolescents and Young Adults With Relapsed or Refractory Sarcomas

Dana-Farber Cancer Institute

Phase 1/2 Recruiting
63 enrolled
Sarcoma

Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Desmoplastic Small Round Cell Tumor

NCT01189643 2025-09-05

Irinotecan, Temozolomide and Bevacizumab in Combination With Existing High Dose Alkylator Based Chemotherapy for Treatment of Newly Diagnosed Patients With Desmoplastic Small Round Cell Tumor

Memorial Sloan Kettering Cancer Center

Phase EARLY_PHASE1 Active not recruiting
15 enrolled
Sarcoma

Sarcoma, Desmoplastic Small Round Cell Tumor

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