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Phase

Phase 1/2 1

Status

Recruiting 1

Sponsor Class

OTHER 1

Study Type

Interventional 1

Sponsor

Cancer Type

Sarcoma 1CNS 1

Conditions

Breast Neoplasms 3Pain 2Neoplasm Metastasis 2Stomach Neoplasms 1Sarcoma, Synovial 1Sarcoma, Ewing 1Sarcoma, Clear Cell 1Sarcoma, Alveolar Soft Part 1Sarcoma 1Rhabdomyosarcoma 1Rhabdoid Tumor 1Osteosarcoma 1Neuroblastoma 1Nerve Sheath Neoplasms 1Neoplasms, Plasma Cell 1Myoepithelioma 1Multiple Myeloma 1Kidney Neoplasms 1Humoral Hypercalcemia Of Malignancy 1Giant Cell Tumors of Bone 1Desmoplastic Small Round Cell Tumor 1Chordoma 1Carcinoma, Renal Cell 1Ascites 1Adenocarcinoma 1

Interventions

Cyclophosphamide 2seclidemstat 1prexasertib 1pegylated granulocyte colony-stimulating factor 1pegfilgrastim 1Zoledronic Acid 1Vinorelbine 1Vincristine 1Topotecan 1Temozolomide 1Ramucirumab 1PM 01183 1Irinotecan 1HhAntag691 1Granulocyte Colony-Stimulating Factor 1Filgrastim 12,2-dimethyl-N-(6-oxo-6,7-dihydro-5H-dibenzo(b,d)azepin-7-yl)-N'-(2,2,3,3,3-pentafluoropropyl)malonamide 1

Date Range

30 days90 days1 yearAll

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Clinical Trials

1 trials
RecentStart dateEnrollment
Phase 1/2 × Desmoplastic Small Round Cell Tumor × Zoledronic Acid × Clear all
NCT06625190 2026-03-11

Alpha/Beta T and B Cell Depletion With Zoledronic Acid for Solid Tumors

University of Florida

Phase 1/2 Recruiting
27 enrolled
CNSSarcoma

Chordoma, Myoepithelioma, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Sarcoma, Synovial, Sarcoma, Clear Cell, Sarcoma, Alveolar Soft Part, Nerve Sheath Neoplasms, Rhabdoid Tumor, Desmoplastic Small Round Cell Tumor

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