Announcements Trials
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Phase

Phase 1/2 1

Status

Completed 1

Sponsor Class

OTHER 1

Study Type

Interventional 1

Sponsor

Cancer Type

Sarcoma 1

Conditions

Neoplasms 4Neoplasm Metastasis 3Colorectal Neoplasms 2Central Nervous System Neoplasms 2Carcinoma, Non-Small-Cell Lung 2Squamous Cell Carcinoma of Head and Neck 1Solid Tumor 1Small Cell Lung Carcinoma 1Rhabdomyosarcoma 1Ovarian Neoplasms 1Microphthalmia, Isolated, with Coloboma 5 1Medulloblastoma 1Leukemia, Myelomonocytic, Chronic 1Leukemia, Myeloid, Acute 1Head and Neck Neoplasms 1Fanconi Anemia 1Desmoplastic Small Round Cell Tumor 1Carcinoma, Squamous Cell 1Breast Neoplasms 1Brain Neoplasms 1Anus Neoplasms 1Advanced Cancer 1

Interventions

Cyclophosphamide 6Vincristine 5Etoposide 5Doxorubicin 5Radiotherapy 4Ifosfamide 4Filgrastim 3Carboplatin 3Peripheral Blood Stem Cell Transplantation 2Neoadjuvant Therapy 2Epirubicin 2Dactinomycin 2Cisplatin 2Chemotherapy, Adjuvant 2Brachytherapy 2tanespimycin 1prexasertib 1pazopanib 1ganitumab 1fludarabine phosphate 1exatecan 1cixutumumab 1Vinorelbine 1Topotecan 1Thiotepa 1Taxes 1Tacrolimus 1Sunitinib 1Sirolimus 1Ramucirumab 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Completed × Desmoplastic Small Round Cell Tumor × prexasertib × Clear all
NCT04095221 2025-02-20

A Study of the Drugs Prexasertib, Irinotecan, and Temozolomide in People With Desmoplastic Small Round Cell Tumor and Rhabdomyosarcoma

Memorial Sloan Kettering Cancer Center

Phase 1/2 Completed
21 enrolled
Sarcoma

Rhabdomyosarcoma, Desmoplastic Small Round Cell Tumor

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