Clinical Trials

107 trials
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Observational × Diabetes Mellitus × Clear all
NCT04306939 2026-01-07

GREAT1

University of Pittsburgh

Suspended
120,000 enrolled
Gastrointestinal

Arthritis, Rheumatoid, Celiac Disease, Cholecystitis, Cholelithiasis, Chronic Disease, Crohn Disease, Cystic Fibrosis, Diabetes Mellitus, Fibrosis, Gastritis, Hepatitis, Liver Cirrhosis, Biliary, Multiple Sclerosis, Pancreatic Cyst, Exocrine Pancreatic Insufficiency, Pancreatitis, Inflammatory Bowel Diseases, Irritable Bowel Syndrome, Dyslipidemias, Pancreatitis, Chronic, Renal Insufficiency, Chronic, Chronic Pain, Non-alcoholic Fatty Liver Disease

NCT04031469 2025-07-31

A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Disease

ProgenaBiome

Suspended
1,000 enrolled
GastrointestinalOtherOther solid neoplasmThoracic

Autism Spectrum Disorder, Bipolar and Related Disorders, Post-Lyme Disease Syndrome, Generalized Anxiety Disorder, Acne Vulgaris, Alzheimer Disease, Amyotrophic Lateral Sclerosis, Anxiety Disorders, Arthritis, Rheumatoid, Autistic Disorder, Bipolar Disorder, Celiac Disease, Colitis, Ulcerative, Colonic Neoplasms, Compulsive Personality Disorder, Constipation, Crohn Disease, Depression, Depressive Disorder, Major, Diabetes Mellitus, Eczema, Epidermolysis Bullosa, Gout, Hypercholesterolemia, Lyme Disease, Mesothelioma, Migraine Disorders, Multiple Sclerosis, Myasthenia Gravis, Neoplasms, Obsessive-Compulsive Disorder, Parkinson Disease, Psoriasis, Colorectal Neoplasms, Fatigue Syndrome, Chronic, Multiple Sclerosis, Chronic Progressive, Multiple Sclerosis, Relapsing-Remitting, Lyme Neuroborreliosis, Irritable Bowel Syndrome

NCT03655223 2025-04-04

Early Check: Expanded Screening in Newborns

RTI International

Enrolling by invitation
30,000 enrolled
Classical hematologyEndocrineHead & NeckOther solid neoplasm

Severe combined immunodeficiency due to adenosine deaminase deficiency, 3-methylcrotonyl CoA carboxylase 1 deficiency, 3-methylcrotonyl CoA carboxylase 2 deficiency, 3-Hydroxyacyl-CoA Dehydrogenase Deficiency, Ataxia with vitamin E deficiency, Beta ketothiolase deficiency, Bile acid synthesis defect, congenital, 2, Carnitine palmitoyl transferase 1A deficiency, Carnitine palmitoyl transferase 2 deficiency, Creatine deficiency, X-linked, Adrenocorticotropic hormone deficiency, Maple syrup urine disease, type 1A, Maple syrup urine disease, type 1B, Maple syrup urine disease, type 2, Congenital disorder of glycosylation type 1B, Medium chain acyl CoA dehydrogenase deficiency, N-acetyl glutamate synthetase deficiency, Niemann-Pick disease, type C2, Pyridoxine-dependent epilepsy, VLCAD deficiency, Primary hyperoxaluria type 1, Primary hyperoxaluria type 2, Waardenburg syndrome type 2, Waardenburg syndrome type 2A, Usher syndrome, type 1B, Usher syndrome, type 1C, Usher syndrome, type 1F, Amaurosis congenita of Leber, type 2, Glut1 Deficiency Syndrome, Glutaric Acidemia I, Glutathione synthetase deficiency, Brown-Vialetto-Van Laere syndrome, Methylenetetrahydrofolate reductase deficiency, Methylmalonic acidemia with homocystinuria, Methylmalonic aciduria cblA type, Methylmalonic aciduria cblB type, Pitt-Hopkins syndrome, Stickler syndrome, type 1, Stickler syndrome, type 2, Segawa syndrome, autosomal recessive, Guanidinoacetate methyltransferase deficiency, Basal ganglia disease, biotin-responsive, Acidemia, isovaleric, Acrodermatitis enteropathica, Adenine phosphoribosyltransferase deficiency, Adrenal hyperplasia, congenital, type 5, 3-Hydroxy-3-Methylglutaryl-CoA Lyase Deficiency, Hyperinsulinemic hypoglycemia, familial, 6, HHH syndrome, Glycogen Storage Disease IB, Hyperphenylalaninemia, BH4-Deficient, B, Thyroid Dyshormonogenesis 3, Thyroid Dyshormonogenesis 5, Glycogen Storage Disease IC, Carnitine-Acylcarnitine Translocase Deficiency, Glycogen Storage Disease IXB, Thyroid Dyshormonogenesis 2A, Intrinsic Factor Deficiency, Hyperparathyroidism, Neonatal Severe Primary, Diabetes Mellitus, Permanent Neonatal, With Neurologic Features, Diabetes Mellitus, Permanent Neonatal, Maturity-Onset Diabetes of the Young, Type 4, Thyroid Dyshormonogenesis 6, Thyroid Dyshormonogenesis 1, Tuberous Sclerosis 1, Molybdenum Cofactor Deficiency, Complementation Group A, Methylmalonic Aciduria due to Methylmalonyl-CoA Mutase Deficiency, Homocystinuria-Megaloblastic Anemia due to Defect in Cobalamin Metabolism, CblE Complementation Type, Tuberous Sclerosis 2, Pyridoxamine 5-Prime-Phosphate Oxidase Deficiency, Trifunctional Protein Deficiency With Myopathy And Neuropathy, Arginine-Glycine Amidinotransferase Deficiency, Jervell And Lange-Nielsen Syndrome 2, Glycogen Storage Disease, Type IXA2, Pituitary Hormone Deficiency, Combined, 1, Glycogen Storage Disease IXC, Anemia, Sickle Cell, Hemophilia B, Congenital Hypothyroidism, Cystic Fibrosis, Cystinosis, Diabetes Mellitus, Disease, Epilepsy, Epilepsies, Myoclonic, Factor VII Deficiency, Factor X Deficiency, Fragile X Syndrome, Fructose Intolerance, Galactosemias, Glycogen Storage Disease Type I, Glucosephosphate Dehydrogenase Deficiency, Glycogen Storage Disease Type II, Granulomatous Disease, Chronic, Hemophilia A, Hepatolenticular Degeneration, Homocystinuria, Hypophosphatasia, Menkes Kinky Hair Syndrome, Leukodystrophy, Globoid Cell, Leukodystrophy, Metachromatic, Mucopolysaccharidosis I, Mucopolysaccharidosis III, Mucopolysaccharidosis IV, Mucopolysaccharidosis VI, Muscular Atrophy, Spinal, Nephritis, Hereditary, Phenylketonurias, Prader-Willi Syndrome, Pseudohypoaldosteronism, Retinoblastoma, Stress Disorders, Post-Traumatic, Waardenburg Syndrome, Wolman Disease, Fructose-1,6-Diphosphatase Deficiency, Rett Syndrome, Gyrate Atrophy, Mucopolysaccharidosis II, Mucopolysaccharidosis VII, beta-Thalassemia, Angelman Syndrome, Canavan Disease, Multiple Endocrine Neoplasia Type 2b, Peroxisomal Disorders, Smith-Lemli-Opitz Syndrome, Xanthomatosis, Cerebrotendinous, Citrullinemia, Hyperargininemia, Ornithine Carbamoyltransferase Deficiency Disease, Carbamoyl-Phosphate Synthase I Deficiency Disease, Tyrosinemias, Muscular Dystrophy, Duchenne, Aortic Stenosis, Supravalvular, Hermanski-Pudlak Syndrome, Biotinidase Deficiency, Holocarboxylase Synthetase Deficiency, Jervell-Lange Nielsen Syndrome, Mineralocorticoid Excess Syndrome, Apparent, Congenital Hyperinsulinism, Niemann-Pick Disease, Type A, Niemann-Pick Disease, Type C, Familial Hypophosphatemic Rickets, X-Linked Combined Immunodeficiency Diseases, Propionic Acidemia, von Willebrand Disease, Type 3, Argininosuccinic Aciduria, Barth Syndrome, Liddle Syndrome

NCT06203106 2025-03-03

NYSCF Scientific Discovery Biobank

New York Stem Cell Foundation Research Institute

Recruiting
10,000 enrolled
Gynecologic

Corticobasal Degeneration, Alzheimer Disease, Amyotrophic Lateral Sclerosis, Uterine Cervical Neoplasms, Dementia, Diabetes Mellitus, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2, Huntington Disease, Macular Degeneration, Multiple Sclerosis, Neuronal Ceroid-Lipofuscinoses, Ovarian Neoplasms, Parkinson Disease, Stress Disorders, Post-Traumatic, Supranuclear Palsy, Progressive, Uterine Neoplasms, Vaginal Neoplasms, Vulvar Neoplasms, Multiple System Atrophy, Parkinsonian Disorders, Lewy Body Disease, Frontotemporal Dementia

NCT06583395 2024-11-01

QUANTUM

VitaMed Research LLC

Enrolling by invitation
3,000 enrolled
BreastCNSDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckLymphoidThoracic

Amyotrophic Lateral Sclerosis, Anxiety Disorders, Arthritis, Rheumatoid, Asthma, Atrial Fibrillation, Brain Neoplasms, Breast Neoplasms, Cerebral Palsy, Cluster Headache, Colitis, Ulcerative, Colonic Neoplasms, Crohn Disease, Deafness, Depression, Diabetes Mellitus, Eczema, Epilepsy, Fibromyalgia, Heart Failure, Hypertension, Hyperthyroidism, Hypothyroidism, Infertility, Leiomyoma, Lung Neoplasms, Lyme Disease, Lymphoma, Macular Degeneration, Migraine Disorders, Multiple Sclerosis, Neoplasms, Osteoarthritis, Osteoporosis, Ovarian Cysts, Ovarian Neoplasms, Parkinson Disease, Phantom Limb, Prostatic Neoplasms, Psoriasis, Skin Neoplasms, Spinal Cord Injuries, Spinal Stenosis, Stress Disorders, Post-Traumatic, Thyroid Neoplasms, Tinnitus, Fatigue Syndrome, Chronic, Tension-Type Headache, Stroke, Pulmonary Disease, Chronic Obstructive, Irritable Bowel Syndrome, Renal Insufficiency, Chronic, Angina, Stable

NCT05635266 2024-05-07

Tissue Repository Providing Annotated Biospecimens for Approved Investigator-directed Biomedical Research Initiatives

Sanguine Biosciences

Recruiting
20,000 enrolled
Classical hematologyGenitourinaryHead & NeckLymphoidOther hematologic neoplasmPlasma cell

red meat allergy, Alopecia Areata, Alzheimer Disease, Amyloidosis, Anemia, Sickle Cell, Arthritis, Asthma, Autistic Disorder, Behcet Syndrome, Celiac Disease, Colitis, Ulcerative, Crohn Disease, Cystic Fibrosis, Dermatitis, Atopic, Diabetes Mellitus, Epilepsies, Myoclonic, Fibrosis, Fibromyalgia, Graves Disease, Heart Diseases, Hepatitis, Hypersensitivity, Kidney Diseases, Leukemia, Lupus Erythematosus, Systemic, Lymphoma, Macular Degeneration, Multiple Sclerosis, Myasthenia Gravis, Neoplasms, Parkinson Disease, Pemphigus, Psoriasis, Schizophrenia, Spondylitis, Ankylosing, Thyroid Diseases, Vasculitis, Vitiligo, beta-Thalassemia, Hidradenitis Suppurativa, Hepatitis, Autoimmune, Stroke, Pulmonary Disease, Chronic Obstructive, Scleroderma, Diffuse

NCT01931644 2024-04-18

At-Home Research Study for Patients With Autoimmune, Inflammatory, Genetic, Hematological, Infectious, Neurological, CNS, Oncological, Respiratory, Metabolic Conditions

Sanguine Biosciences

Completed
17,667 enrolled
BreastClassical hematologyDermatologicGastrointestinalGenitourinaryGynecologicLymphoidOther hematologic neoplasmPlasma cellThoracic

Generalized Anxiety Disorder, Acquired Immunodeficiency Syndrome, Alopecia Areata, Anemia, Sickle Cell, Asthma, Bipolar Disorder, Breast Neoplasms, Celiac Disease, Uterine Cervical Neoplasms, Colitis, Ulcerative, Colonic Neoplasms, Crohn Disease, Cystic Fibrosis, Depression, Diabetes Mellitus, Down Syndrome, Endometriosis, Epilepsy, Glucosephosphate Dehydrogenase Deficiency, Hepatitis B, Huntington Disease, Sleep Initiation and Maintenance Disorders, Kidney Neoplasms, Polycystic Kidney Diseases, Leukemia, Lung Neoplasms, Lupus Erythematosus, Systemic, Lupus Nephritis, Lymphoma, Melanoma, Multiple Myeloma, Multiple Sclerosis, Muscular Atrophy, Spinal, Myositis, Myotonic Dystrophy, Ovarian Neoplasms, Pancreatic Neoplasms, Parkinson Disease, Prostatic Neoplasms, Psoriasis, Purpura, Thrombotic Thrombocytopenic, Rosacea, Sickle Cell Trait, Sjogren's Syndrome, Skin Neoplasms, Spondylitis, Ankylosing, Telangiectasia, Hereditary Hemorrhagic, Colorectal Neoplasms, Arthritis, Psoriatic, Purpura, Thrombocytopenic, Idiopathic, beta-Thalassemia, Polyradiculoneuropathy, Chronic Inflammatory Demyelinating, Muscular Dystrophy, Duchenne, Muscular Dystrophy, Facioscapulohumeral, Pulmonary Disease, Chronic Obstructive, Scleroderma, Diffuse, Renal Insufficiency, Chronic

NCT03840928 2023-12-13

PatientSpot Formerly Known as ArthritisPower

Global Healthy Living Foundation

Unknown
40,000 enrolled
CNSDermatologicOtherThoracic

Intervertebral disc disease, Undifferentiated Connective Tissue Diseases, Axial Spondyloarthritis, Alopecia, Alzheimer Disease, Amyotrophic Lateral Sclerosis, Angina, Unstable, Arrhythmias, Cardiac, Arthritis, Juvenile, Arthritis, Rheumatoid, Asthma, Ataxia, Brain Neoplasms, Intracranial Aneurysm, Cluster Headache, Crohn Disease, Cystic Fibrosis, Dermatomyositis, Diabetes Mellitus, Hyperostosis, Diffuse Idiopathic Skeletal, Eczema, Epilepsy, Fibromyalgia, Gout, Craniocerebral Trauma, Headache, Heart Defects, Congenital, Heart Failure, Heart Valve Diseases, Hydrocephalus, Hypertension, Lung Neoplasms, Meningitis, Multiple Sclerosis, Muscular Dystrophies, Myocardial Infarction, Myositis, Obesity, Osteoarthritis, Osteoporosis, Parkinson Disease, Polychondritis, Relapsing, Polymyalgia Rheumatica, Psoriasis, Sleep Apnea Syndromes, Spinal Cord Injuries, Spondylitis, Ankylosing, Giant Cell Arteritis, Granulomatosis with Polyangiitis, Inflammatory Bowel Diseases, Arthritis, Psoriatic, Polymyositis, Tension-Type Headache, Guillain-Barre Syndrome, Bell Palsy, Stroke, Neurocutaneous Syndromes, Pulmonary Disease, Chronic Obstructive, Scleroderma, Diffuse, Peripheral Arterial Disease

NCT06072287 2023-10-12

LTC

King's College London

Unknown
600 enrolled
Classical hematologyOther

Psychological Well-Being, Post-Acute COVID-19 Syndrome, Acquired Immunodeficiency Syndrome, Amyotrophic Lateral Sclerosis, Anemia, Sickle Cell, Anxiety Disorders, Arthritis, Arthritis, Rheumatoid, Asthma, Atrial Fibrillation, Celiac Disease, Cerebrovascular Disorders, Chronic Disease, Cystic Fibrosis, Dementia, Depression, Diabetes Mellitus, Eczema, Endometriosis, Epilepsy, Fibromyalgia, Heart Diseases, Heart Failure, Hepatitis, Hypertension, Liver Diseases, Migraine Disorders, Multiple Sclerosis, Neoplasms, Nervous System Diseases, Obesity, Osteoarthritis, Osteoporosis, Pain, Parkinson Disease, Spondylitis, Fatigue Syndrome, Chronic, Hidradenitis Suppurativa, Stroke, Pulmonary Disease, Chronic Obstructive, Postural Orthostatic Tachycardia Syndrome