Announcements Trials
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Phase

Phase 2 3Phase 1/2 3Phase 1 2Phase NA 1

Status

Recruiting 1Not yet recruiting 1Completed 1

Sponsor Class

OTHER 3

Study Type

Interventional 3

Sponsor

Cancer Type

CNS 3Sarcoma 1

Conditions

Carcinoma, Non-Small-Cell Lung 48Neoplasms 27Colorectal Neoplasms 26Neoplasm Metastasis 24Recurrence 22Ovarian Neoplasms 22Pancreatic Neoplasms 21Breast Neoplasms 20Squamous Cell Carcinoma of Head and Neck 18Prostatic Neoplasms 18Melanoma 17Glioblastoma 15Lymphoma, Large B-Cell, Diffuse 14Precursor Cell Lymphoblastic Leukemia-Lymphoma 13Lymphoma, Non-Hodgkin 13Endometrial Neoplasms 13Multiple Myeloma 12Lung Neoplasms 12Colonic Neoplasms 12Triple Negative Breast Neoplasms 11Carcinoma, Renal Cell 11Stomach Neoplasms 10Leukemia, Myeloid, Acute 10Glioma 10Gastrointestinal Neoplasms 10Rectal Neoplasms 9Lymphoma, Follicular 9Lymphoma 9Head and Neck Neoplasms 8Burkitt Lymphoma 8

Interventions

Temozolomide 1Nivolumab 1Eflornithine 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Phase 1/2 × Diffuse Intrinsic Pontine Glioma × 30 days × Clear all
NCT04911621 2026-06-05

ADDICT-pedGLIO

University Hospital, Antwerp

Phase 1/2 Completed
10 enrolled
CNS

Diffuse Intrinsic Pontine Glioma, Glioma

NCT06465199 2026-06-03

Eflornithine (DFMO) and AMXT 1501 for Neuroblastoma, CNS Tumors, and Sarcomas

Milton S. Hershey Medical Center

Phase 1/2 Recruiting
289 enrolled
CNSSarcoma

Diffuse Intrinsic Pontine Glioma, Neuroblastoma, Sarcoma, Ewing, Osteosarcoma, Neuroectodermal Tumors, Primitive, Rhabdoid Tumor

NCT06639607 2026-06-03

PRiME II

Washington University School of Medicine

Phase 1/2 Not yet recruiting
68 enrolled
CNS

Diffuse Intrinsic Pontine Glioma, Ependymoma, Medulloblastoma, Recurrence

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