Announcements Trials
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Phase

Phase 1 11Phase 1/2 6Phase 2 5Phase NA 1Phase EARLY_PHASE1 1

Status

Recruiting 4Not yet recruiting 1Completed 1

Sponsor Class

OTHER 5NETWORK 1

Study Type

Interventional 6

Sponsor

Cancer Type

CNS 6Sarcoma 1Lymphoid 1

Conditions

Carcinoma, Non-Small-Cell Lung 112Breast Neoplasms 79Neoplasms 74Neoplasm Metastasis 63Colorectal Neoplasms 62Prostatic Neoplasms 57Recurrence 56Pancreatic Neoplasms 54Leukemia, Myeloid, Acute 54Ovarian Neoplasms 53Multiple Myeloma 50Melanoma 39Glioblastoma 38Squamous Cell Carcinoma of Head and Neck 33Lung Neoplasms 33Triple Negative Breast Neoplasms 31Lymphoma, Non-Hodgkin 30Endometrial Neoplasms 30Precursor Cell Lymphoblastic Leukemia-Lymphoma 29Lymphoma 27Carcinoma, Renal Cell 27Lymphoma, Large B-Cell, Diffuse 26Stomach Neoplasms 25Lymphoma, B-Cell 25Carcinoma, Hepatocellular 24Advanced Solid Tumor 24Small Cell Lung Carcinoma 23Leukemia, Lymphocytic, Chronic, B-Cell 23Burkitt Lymphoma 23Brain Neoplasms 23

Interventions

lutetium Lu 177 dotatate 1Temozolomide 1Specimen Handling 1Nivolumab 1Fluid Therapy 1Eflornithine 1CBLC137 1Biopsy 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

6 trials
RecentStart dateEnrollment
Phase 1/2 × Diffuse Intrinsic Pontine Glioma × 90 days × Clear all
NCT04911621 2026-06-05

ADDICT-pedGLIO

University Hospital, Antwerp

Phase 1/2 Completed
10 enrolled
CNS

Diffuse Intrinsic Pontine Glioma, Glioma

NCT06465199 2026-06-03

Eflornithine (DFMO) and AMXT 1501 for Neuroblastoma, CNS Tumors, and Sarcomas

Milton S. Hershey Medical Center

Phase 1/2 Recruiting
289 enrolled
CNSSarcoma

Diffuse Intrinsic Pontine Glioma, Neuroblastoma, Sarcoma, Ewing, Osteosarcoma, Neuroectodermal Tumors, Primitive, Rhabdoid Tumor

NCT06639607 2026-06-03

PRiME II

Washington University School of Medicine

Phase 1/2 Not yet recruiting
68 enrolled
CNS

Diffuse Intrinsic Pontine Glioma, Ependymoma, Medulloblastoma, Recurrence

NCT04870944 2026-05-05

CBL0137 for the Treatment of Relapsed or Refractory Solid Tumors, Including CNS Tumors and Lymphoma

Children's Oncology Group

Phase 1/2 Recruiting
63 enrolled
CNSLymphoid

Diffuse Intrinsic Pontine Glioma, Lymphoma

NCT05278208 2026-04-13

Lutathera for Treatment of Recurrent or Progressive High-Grade CNS Tumors

Nationwide Children's Hospital

Phase 1/2 Recruiting
65 enrolled
CNS

Diffuse Intrinsic Pontine Glioma, Ependymoma, Glioma, Medulloblastoma, Meningioma, Neoplasms, Germ Cell and Embryonal, Central Nervous System Neoplasms

NCT07501156 2026-03-30

H3K27M-specific Immune Effector Cells Targeting DMG/DIPG

Shenzhen Geno-Immune Medical Institute

Phase 1/2 Recruiting
30 enrolled
CNS

Diffuse Intrinsic Pontine Glioma

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