Announcements Trials
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Phase

Phase 1 3Phase 2 2

Status

Terminated 2Completed 1

Sponsor Class

INDUSTRY 2OTHER 1

Study Type

Interventional 3

Sponsor

Cancer Type

CNS 3Sarcoma 1

Conditions

Precursor Cell Lymphoblastic Leukemia-Lymphoma 72Multiple Myeloma 70Leukemia, Myeloid, Acute 70Lymphoma, Large B-Cell, Diffuse 61Lymphoma, Non-Hodgkin 58Leukemia, Lymphocytic, Chronic, B-Cell 57Lymphoma 56Melanoma 52Leukemia 52Breast Neoplasms 49Burkitt Lymphoma 48Myelodysplastic Syndromes 44Recurrence 41Lymphoma, Follicular 41Lymphoma, B-Cell 38Lymphoma, Mantle-Cell 37Ovarian Neoplasms 32Neuroblastoma 32Lymphoma, B-Cell, Marginal Zone 27Sarcoma 26Neoplasms 26Carcinoma, Non-Small-Cell Lung 25Hodgkin Disease 24Neoplasm Metastasis 23Triple Negative Breast Neoplasms 18Carcinoma, Renal Cell 18Neoplasms, Plasma Cell 17Hematologic Neoplasms 17Leukemia, Myelomonocytic, Chronic 16Colorectal Neoplasms 16

Interventions

Radiotherapy 6Radiation 3Panobinostat 3Cyclophosphamide 3ribociclib 2Temozolomide 2Specimen Handling 2Magnetic Resonance Spectroscopy 2Everolimus 2Etoposide 2Dasatinib 2vandetanib 1temsirolimus 1spartalizumab 1sargramostim 1reolysin 1pembrolizumab 1ovex 1marizomib 1irinotecan sucrosofate 1gallium maltolate 1etoposide phosphate 1crenolanib 1balstilimab 1adavosertib 1abemaciclib 1X-Rays 1Vorinostat 1Vaccines 1Topotecan 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Phase 1 × Diffuse Intrinsic Pontine Glioma × Cyclophosphamide × Clear all
NCT03396575 2025-10-29

BRAVO

University of Florida

Phase 1 Terminated
11 enrolled
CNS

Diffuse Intrinsic Pontine Glioma, Brain Neoplasms, Influenza, Human, Xanthomatosis, Cerebrotendinous

NCT04239092 2025-07-17

9-ING-41 in Pediatric Patients With Refractory Malignancies.

Actuate Therapeutics Inc.

Phase 1 Terminated
40 enrolled
CNS

Diffuse Intrinsic Pontine Glioma, Meningioma, Neoplasms, Neuroblastoma

NCT02502708 2020-06-04

Study of the IDO Pathway Inhibitor, Indoximod, and Temozolomide for Pediatric Patients With Progressive Primary Malignant Brain Tumors

Lumos Pharma

Phase 1 Completed
81 enrolled
CNSSarcoma

Diffuse Intrinsic Pontine Glioma, Brain Neoplasms, Ependymoma, Glioblastoma, Glioma, Medulloblastoma, Gliosarcoma

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