Clinical Trials

Digestive System Neoplasms

NCT07222800 2026-04-08

Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer

Phase 3 Recruiting

800 enrolled

EndocrineGastrointestinalHead & NeckNETSarcomaThoracic

Colonic Diseases, Colonic Neoplasms, Digestive System Diseases, Digestive System Neoplasms, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Intestinal Diseases, Intestinal Neoplasms, Neoplasm Metastasis, Neoplasms by Site, Rectal Diseases, Colorectal Neoplasms

NCT03093116 2026-04-03

TRIDENT-1

Phase 1/2 Recruiting

500 enrolled 5 FDA

Adenocarcinoma, Bronchial Neoplasms, Carcinoma, Carcinoma, Bronchogenic, Carcinoma, Non-Small-Cell Lung, Colonic Diseases, Colonic Neoplasms, Digestive System Neoplasms, Endocrine System Diseases, Endocrine Gland Neoplasms, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Head and Neck Neoplasms, Intestinal Diseases, Intestinal Neoplasms, Lung Diseases, Lung Neoplasms, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Respiratory Tract Diseases, Respiratory Tract Neoplasms, Sarcoma, Thoracic Neoplasms, Thyroid Diseases, Thyroid Neoplasms, Neuroectodermal Tumors, Carcinoma, Neuroendocrine, Neuroendocrine Tumors

NCT06096779 2026-04-03

Kirros

Phase 2 Recruiting

30 enrolled

Digestive System Neoplasms, Fatty Liver, Fibrosis, Carcinoma, Hepatocellular, Liver Diseases, Liver Neoplasms

NCT07377487 2026-03-30

INDIGO

EndocrineGastrointestinalNET

51 enrolled

Carcinoma, Colonic Diseases, Digestive System Diseases, Digestive System Neoplasms, Carcinoma, Hepatocellular, Liver Diseases, Liver Neoplasms, Neoplasm Metastasis, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Glandular and Epithelial, Colorectal Neoplasms, Carcinoma, Neuroendocrine, Neuroendocrine Tumors

NCT05063565 2026-03-27

ROWAN

Phase 2 Active not recruiting

100 enrolled

Adenocarcinoma, Carcinoma, Digestive System Diseases, Digestive System Neoplasms, Carcinoma, Hepatocellular, Liver Diseases, Liver Neoplasms, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Glandular and Epithelial

NCT05039177 2026-03-25

HERKULES-3

Phase 1/2 Completed

101 enrolled

Digestive System Neoplasms, Gastrointestinal Neoplasms, Pancreatic Neoplasms, Colorectal Neoplasms

NCT03221335 2026-03-20

EUS-guided RFA for Solid Abdominal Neoplasms

GastrointestinalGenitourinary

30 enrolled

Carcinoma, Renal Cell, Digestive System Neoplasms

NCT06263205 2026-03-03

Dressing

Phase NA Completed

1,138 enrolled

Phase 1 Active not recruiting

Digestive System Neoplasms, Gastrointestinal Neoplasms, Pain, Postoperative, Surgical Wound Infection

NCT03833700 2026-02-27

A Study of E7386 in Participants With Advanced Solid Tumor Including Colorectal Cancer (CRC)

70 enrolled

EndocrineGastrointestinalNETSarcoma

Gastro-enteropancreatic neuroendocrine tumor, Digestive System Neoplasms, Carcinoma, Hepatocellular, Colorectal Neoplasms, Desmoid Tumors, Adrenocortical Carcinoma

NCT07279428 2026-02-27

A Study of BL-M24D1 in Patients With Locally Advanced or Metastatic Gastrointestinal Tumors and Other Solid Tumors

33 enrolled

Digestive System Neoplasms

NCT07404527 2026-02-13

Bioelectrical Impedance Analysis for Perioperative Fluid Evaluation in Colorectal Cancer Surgery

60 enrolled

Phase 2 Not yet recruiting

Digestive System Neoplasms, Gastrointestinal Neoplasms

NCT07406633 2026-02-12

KQB198 in Combination With Imatinib in Participants With Advanced/Metastatic GIST in 1st Line Setting

46 enrolled

GastrointestinalSarcoma

Digestive System Neoplasms, Gastrointestinal Stromal Tumors

NCT01625351 2026-02-06

A Study of CD45RA+ Depleted Haploidentical Stem Cell Transplantation in Children With Relapsed or Refractory Solid Tumors and Lymphomas

Phase 1 Completed

23 enrolled

CNSDermatologicGastrointestinalGenitourinaryLymphoidSarcoma

Carcinoma, Renal Cell, Digestive System Neoplasms, Carcinoma, Hepatocellular, Lymphoma, Melanoma, Neoplasms, Germ Cell and Embryonal, Wilms Tumor, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Ewing, Adenocarcinoma, Clear Cell, Rhabdoid Tumor

NCT07313579 2026-01-13

G-PEC

Recruiting

200 enrolled

Digestive System Neoplasms, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Stomach Diseases, Stomach Neoplasms

NCT07232407 2026-01-07

A Study of Lutetium [177Lu] BL-ARC001 in Patients With Locally Advanced or Metastatic Gastrointestinal Tumors and Other Solid Tumors

22 enrolled

Digestive System Neoplasms

NCT06715839 2025-12-31

Target-specific immunoPET Imaging of Digestive System Carcinoma

400 enrolled

Phase EARLY_PHASE1 Recruiting

Simpson-Golabi-Behmel syndrome, Appendiceal Neoplasms, Bile Duct Neoplasms, Colonic Neoplasms, Digestive System Neoplasms, Esophageal Neoplasms, Gallbladder Neoplasms, Gastrointestinal Neoplasms, Liver Neoplasms, Neoplasms, Pancreatic Neoplasms, Rectal Neoplasms, Stomach Neoplasms

NCT04960072 2025-12-23

A Study of GC101 TIL in r/r Gastrointestinal Tumors (10hospital)

50 enrolled

Phase 1/2 Not yet recruiting

Digestive System Neoplasms

NCT03508180 2025-12-19

REFYO-R

Phase NA Completed

80 enrolled

GastrointestinalThoracic

Digestive System Neoplasms, Lung Neoplasms, Nausea, Neoplasms, Vomiting

NCT04556344 2025-12-05

EmoVie_K2

Phase NA Completed

26 enrolled

GastrointestinalThoracic

Digestive System Neoplasms, Thoracic Neoplasms

NCT07263594 2025-12-04

A Study of DB-1324 in Advanced/Metastatic Gastrointestinal Tumors

127 enrolled

Digestive System Neoplasms, Gastrointestinal Neoplasms

NCT05980416 2025-11-14

Study of EO-3021 in Adult Patients With Solid Tumors Likely to Express CLDN18.2

Phase 1 Terminated

88 enrolled 18 charts

Phase 2 Not yet recruiting

Adenocarcinoma, Digestive System Neoplasms, Gastrointestinal Neoplasms, Neoplasms, Neoplasms by Site, Stomach Neoplasms

NCT07196540 2025-09-29

IP rmhTNF-NC + Tislelizumab + Palliat RT for GIT Tumor Malignant Ascites After Failed Std Tx

78 enrolled

Digestive System Neoplasms

NCT05262491 2025-09-26

A Study of BL-B01D1 in Patients With Locally Advanced or Metastatic Gastrointestinal Tumor and Other Solid Tumor

96 enrolled

Digestive System Neoplasms, Esophageal Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms, Colorectal Neoplasms

NCT02246725 2025-09-12

ALLAN

Completed

108 enrolled

Phase NA Not yet recruiting

Depression, Digestive System Diseases, Digestive System Neoplasms, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Intestinal Diseases, Intestinal Neoplasms, Colorectal Neoplasms

NCT06794073 2025-08-29

Efficacy and Safety of Multimodal Ablation Combined With PD-1 Monoclonal Antibody, Lenvatinib and TACE in the Treatment of Unresectable Primary Hepatocellular Carcinoma: A Single-Arm, Single-Center Clinical Study

17 enrolled

Phase 3 Active not recruiting

Adenocarcinoma, Digestive System Neoplasms, Carcinoma, Hepatocellular, Liver Neoplasms, Neoplasms, Glandular and Epithelial

NCT04607421 2025-08-14

A Study of Encorafenib Plus Cetuximab With or Without Chemotherapy in People With Previously Untreated Metastatic Colorectal Cancer

831 enrolled 5 FDA

Phase NA Active not recruiting

Colonic Diseases, Colonic Neoplasms, Digestive System Diseases, Digestive System Neoplasms, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Intestinal Diseases, Intestinal Neoplasms, Neoplasms, Rectal Diseases, Rectal Neoplasms, Colorectal Neoplasms

NCT07104877 2025-08-05

A Study of SYS6010 in Combination With SYH2051 in Patients With Advanced Colorectal Cancer and Other Gastrointestinal Tumors

25 enrolled

Digestive System Neoplasms, Stomach Neoplasms, Colorectal Neoplasms

NCT05981235 2025-07-31

Phase 1 Trial of AZD6422 in CLDN18.2+ GI Tumors

Phase 1 Completed

8 enrolled

Digestive System Neoplasms

NCT07067385 2025-07-16

PCV-GSTT

40 enrolled

590 enrolled 58 charts 8 FDA

Digestive System Neoplasms

NCT03037385 2025-05-31

ARROW

Phase 1/2 Completed

EndocrineGastrointestinalHead & NeckNETThoracic

Thyroid Cancer, Papillary, Adenocarcinoma, Adenocarcinoma, Papillary, Bronchial Neoplasms, Carcinoma, Carcinoma, Bronchogenic, Carcinoma, Non-Small-Cell Lung, Colonic Diseases, Colonic Neoplasms, Digestive System Diseases, Digestive System Neoplasms, Endocrine System Diseases, Endocrine Gland Neoplasms, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Head and Neck Neoplasms, Intestinal Diseases, Intestinal Neoplasms, Lung Diseases, Lung Neoplasms, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Glandular and Epithelial, Neoplasms, Nerve Tissue, Respiratory Tract Diseases, Respiratory Tract Neoplasms, Thoracic Neoplasms, Thyroid Diseases, Thyroid Neoplasms, Colorectal Neoplasms, Neuroectodermal Tumors, Carcinoma, Medullary, Carcinoma, Neuroendocrine, Neuroendocrine Tumors, Multiple Endocrine Neoplasia Type 2a

NCT06954077 2025-05-31

A Study of BL-M09D1 in Patients With Locally Advanced or Metastatic Gastrointestinal Tumors and Other Solid Tumors

45 enrolled

Digestive System Neoplasms

NCT01550510 2025-05-06

Research Study of IV Vitamin C in Combination With Irinotecan vs Irinotecan Alone for Advanced Colorectal CA

Phase 1/2 Terminated

4 enrolled 5 charts

Colonic Diseases, Digestive System Diseases, Digestive System Neoplasms, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Intestinal Diseases, Intestinal Neoplasms, Neoplasms, Neoplasms by Site, Rectal Diseases, Colorectal Neoplasms

NCT01555489 2025-05-04

Assessing the Efficacy and Safety of IV Vitamin C in Combination With Standard Chemotherapy for Pancreatic Ca

Phase 2 Terminated

11 enrolled 8 charts

Digestive System Diseases, Digestive System Neoplasms, Endocrine System Diseases, Endocrine Gland Neoplasms, Neoplasms, Neoplasms by Site, Pancreatic Diseases, Pancreatic Neoplasms

NCT06940102 2025-04-23

Real-World Study on Nano-Crystalline Megestrol Acetate for Cachexia in TKI-Treated Advanced Digestive Tumors

Recruiting

120 enrolled