Announcements Trials
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Phase

Phase 1/2 1Phase 1 1

Status

Completed 1

Sponsor Class

INDUSTRY 1

Study Type

Interventional 1

Sponsor

Cancer Type

Gastrointestinal 1

Conditions

Breast Neoplasms 16Triple Negative Breast Neoplasms 2Squamous Cell Carcinoma of Head and Neck 2Neoplasm Metastasis 2Melanoma 2Leukemia, Myeloid, Acute 2Head and Neck Neoplasms 2Endometrial Neoplasms 2Carcinoma, Non-Small-Cell Lung 2Breast Diseases 2Uterine Cervical Neoplasms 1Solid Tumors Refractory to Standard Therapy 1Solid Tumors 1Solid Tumor, Adult 1Precursor Cell Lymphoblastic Leukemia-Lymphoma 1Pancreatic Neoplasms 1Ovarian Neoplasms 1Neoplasms by Site 1Neoplasms 1Liposarcoma, Myxoid 1Liposarcoma 1Kidney Neoplasms 1Human Epidermal Growth Factor 2 Negative Carcinoma of Breast 1Hereditary Sensory and Autonomic Neuropathies 1HER2-positive Breast Cancer 1Glioblastoma 1Gastrointestinal Neoplasms 1Fallopian Tube Neoplasms 1Esophageal Neoplasms 1ER+ HER2- Advanced Breast Cancer 1

Interventions

Irinotecan 35,10-methylenetetrahydrofolic acid 2tislelizumab 1spartalizumab 1repotrectinib 1pralsetinib 1palbociclib 1encorafenib 1Pemetrexed 1Levoleucovorin 1Leucovorin 1KRN-330 1Immune Checkpoint Inhibitors 1Imatinib Mesylate 1Gemcitabine 1Flucytosine 1Everolimus 1Cisplatin 1Cetuximab 1Capecitabine 1Ascorbic Acid 1Albumin-Bound Paclitaxel 1130-nm albumin-bound paclitaxel 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Phase 1/2 × Digestive System Neoplasms × palbociclib × Clear all
NCT05039177 2026-03-25

HERKULES-3

Erasca, Inc.

Phase 1/2 Completed
101 enrolled
Gastrointestinal

Digestive System Neoplasms, Gastrointestinal Neoplasms, Pancreatic Neoplasms, Colorectal Neoplasms

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