Clinical Trials

Classical hematologyGastrointestinal

220 enrolled

Pathologic Complete Response, Digestive System Neoplasms, Gastrointestinal Neoplasms, Pancreatic Neoplasms, Thrombocytopenia, Colorectal Neoplasms

NCT06794073 2026-05-11

Efficacy and Safety of Multimodal Ablation Combined With PD-1 Monoclonal Antibody, Lenvatinib and TACE in the Treatment of Unresectable Primary Hepatocellular Carcinoma: A Single-Arm, Single-Center Clinical Study

17 enrolled

Adenocarcinoma, Digestive System Neoplasms, Carcinoma, Hepatocellular, Liver Neoplasms, Neoplasms, Glandular and Epithelial

NCT04929015 2026-05-04

Peritoneal Carcinomatosis Leveraging ctDNA Guided Treatment in GI Cancer Study (PERICLES Study)

Phase NA Suspended

GastrointestinalGynecologic

Digestive System Neoplasms, Carcinoma, Hepatocellular, Peritoneal Neoplasms

NCT04084249 2026-04-29

ctDNA-guided Surveillance for Stage III CRC, a Randomized Intervention Trial

Phase NA Active not recruiting

359 enrolled

Colonic Diseases, Colonic Neoplasms, Digestive System Diseases, Digestive System Neoplasms, Gastrointestinal Neoplasms, Rectal Diseases, Rectal Neoplasms, Colorectal Neoplasms

NCT03221335 2026-03-20

EUS-guided RFA for Solid Abdominal Neoplasms

GastrointestinalGenitourinary

Carcinoma, Renal Cell, Digestive System Neoplasms

NCT06263205 2026-03-03

Dressing

Phase NA Completed

1,138 enrolled

Digestive System Neoplasms, Gastrointestinal Neoplasms, Pain, Postoperative, Surgical Wound Infection

NCT07404527 2026-02-13

Bioelectrical Impedance Analysis for Perioperative Fluid Evaluation in Colorectal Cancer Surgery

60 enrolled

Digestive System Neoplasms, Gastrointestinal Neoplasms

NCT01625351 2026-02-06

A Study of CD45RA+ Depleted Haploidentical Stem Cell Transplantation in Children With Relapsed or Refractory Solid Tumors and Lymphomas

CNSDermatologicGastrointestinalGenitourinaryLymphoidSarcoma

23 enrolled

Carcinoma, Renal Cell, Digestive System Neoplasms, Carcinoma, Hepatocellular, Lymphoma, Melanoma, Neoplasms, Germ Cell and Embryonal, Wilms Tumor, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Ewing, Adenocarcinoma, Clear Cell, Rhabdoid Tumor

NCT06715839 2025-12-31

Target-specific immunoPET Imaging of Digestive System Carcinoma

400 enrolled

Phase 2 Not yet recruiting

Simpson-Golabi-Behmel syndrome, Appendiceal Neoplasms, Bile Duct Neoplasms, Colonic Neoplasms, Digestive System Neoplasms, Esophageal Neoplasms, Gallbladder Neoplasms, Gastrointestinal Neoplasms, Liver Neoplasms, Neoplasms, Pancreatic Neoplasms, Rectal Neoplasms, Stomach Neoplasms

NCT03508180 2025-12-19

REFYO-R

Phase NA Completed

80 enrolled

GastrointestinalThoracic

Digestive System Neoplasms, Lung Neoplasms, Nausea, Neoplasms, Vomiting

NCT04556344 2025-12-05

EmoVie_K2

Phase NA Completed

26 enrolled

GastrointestinalThoracic

Digestive System Neoplasms, Thoracic Neoplasms

NCT07196540 2025-09-29

IP rmhTNF-NC + Tislelizumab + Palliat RT for GIT Tumor Malignant Ascites After Failed Std Tx

78 enrolled

Digestive System Neoplasms

NCT05981235 2025-07-31

Phase 1 Trial of AZD6422 in CLDN18.2+ GI Tumors

8 enrolled

Digestive System Neoplasms

NCT07067385 2025-07-16

PCV-GSTT

40 enrolled

Digestive System Neoplasms

NCT01550510 2025-05-06

Research Study of IV Vitamin C in Combination With Irinotecan vs Irinotecan Alone for Advanced Colorectal CA

Phase 1/2 Terminated

4 enrolled 5 charts

Colonic Diseases, Digestive System Diseases, Digestive System Neoplasms, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Intestinal Diseases, Intestinal Neoplasms, Neoplasms, Neoplasms by Site, Rectal Diseases, Colorectal Neoplasms

NCT01555489 2025-05-04

Assessing the Efficacy and Safety of IV Vitamin C in Combination With Standard Chemotherapy for Pancreatic Ca

Phase 2 Terminated

11 enrolled 8 charts

Digestive System Diseases, Digestive System Neoplasms, Endocrine System Diseases, Endocrine Gland Neoplasms, Neoplasms, Neoplasms by Site, Pancreatic Diseases, Pancreatic Neoplasms

NCT05646511 2025-04-03

ENSEMBLE

Phase 3 Recruiting

608 enrolled

Digestive System Neoplasms, Gastrointestinal Neoplasms, Intestinal Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT06190730 2025-04-03

RECOVER

281 enrolled

Digestive System Neoplasms, Gastrointestinal Neoplasms

NCT03978078 2025-02-12

BCB-CBIO-DIG

200 enrolled

Digestive System Neoplasms, Neoplasms

NCT06775080 2025-01-14

The Use of Propranolol in the Perioperative Period of Resectable Gastrointestinal Tumors

40 enrolled

Digestive System Neoplasms

NCT03535727 2024-12-31

A Study of Gemcitabine, Nab-paclitaxel, Capecitabine, Cisplatin, and Irinotecan in Metastatic Pancreatic Cancer

Phase 1/2 Completed

48 enrolled 24 charts

Adenocarcinoma, Digestive System Diseases, Digestive System Neoplasms, Endocrine System Diseases, Endocrine Gland Neoplasms, Neoplasms, Neoplasms, Glandular and Epithelial, Pancreatic Diseases, Pancreatic Neoplasms

NCT04629326 2024-08-19

PD-L1 Targeting Molecular Imaging of Solid Tumors

Digestive System Neoplasms

NCT04518852 2024-06-25

TACE, Sorafenib and PD-1 Monoclonal Antibody in the Treatment of HCC

Phase 2 Completed

27 enrolled

Digestive System Neoplasms, Carcinoma, Hepatocellular, Liver Diseases, Liver Neoplasms

NCT01832116 2024-05-03

MMOT

GastrointestinalGynecologic

11 enrolled

Adnexal Diseases, Digestive System Diseases, Digestive System Neoplasms, Ovarian Diseases, Ovarian Neoplasms, Pancreatic Diseases, Pancreatic Neoplasms

NCT06340620 2024-04-01

EUS Examination Using EndoSound Vision System vs. Standard Echoendoscope

140 enrolled

Phase 3 Active not recruiting

Bile Duct Diseases, Bile Duct Neoplasms, Digestive System Neoplasms, Gastrointestinal Neoplasms, Pancreatic Cyst, Pancreatic Diseases, Pancreatic Neoplasms

NCT03464305 2024-03-19

ASPIRIN

148 enrolled

Colonic Diseases, Colonic Neoplasms, Digestive System Diseases, Digestive System Neoplasms, Gastrointestinal Neoplasms, Intestinal Diseases, Intestinal Neoplasms, Neoplasms, Neoplasms by Site, Pathologic Processes, Recurrence, Colorectal Neoplasms, Disease Attributes

NCT06223230 2024-01-30

Nutritional Psychological Intervention and Vomit-free Management on Survival and Quality of Life in Advanced Gastrointestinal Tumors

316 enrolled

Digestive System Neoplasms

NCT05646043 2024-01-18

PREHAB - Improving Condition Before Surgery

Phase NA Unknown

40 enrolled

Digestive System Neoplasms, Rectal Neoplasms

NCT05262335 2023-11-28

ALTER-G-001

116 enrolled

Digestive System Neoplasms

NCT06099821 2023-10-26

KN046 Plus Regorafenib or Apatinib in MSI-H Digestive System Cancers Resistant to PD-1/PD-L1 Blockade

39 enrolled

Digestive System Neoplasms

NCT06085365 2023-10-16

Effects of Immunonutrition on the Improvement of Postoperative Adjuvant Chemotherapy Related Adverse Reactions in Patients With Gastrointestinal Tumors

Phase 3 Unknown

324 enrolled

Phase 2 Active not recruiting

Digestive System Neoplasms

NCT05602935 2023-09-28

Efficacy and Safety of SOX Regimen Combined With Camrelizumab as Neoadjuvant Treatment in Locally Advanced Gastric Cancer: a Phase II, Single-arm Study

29 enrolled

Digestive System Diseases, Digestive System Neoplasms, Neoplasms, Neoplasms by Site, Stomach Diseases, Stomach Neoplasms

NCT06019702 2023-09-11

Clinical Study of Personalized mRNA Vaccine Encoding Neoantigen Alone in Subjects With Advanced Digestive System Neoplasms

Digestive System Neoplasms

NCT06026774 2023-09-11

Clinical Study of Personalized mRNA Vaccine Encoding Neoantigen in Subjects With Resected Digestive System Neoplasms

Digestive System Neoplasms

NCT06026800 2023-09-11

Clinical Study of Personalized mRNA Vaccine Encoding Neoantigen in Combination With Standard First-line Treatment in Subjects With Advanced Digestive System Neoplasms

Digestive System Neoplasms

NCT06022692 2023-09-05

HEAIS001

Phase 1/2 Completed

18 enrolled

Hyperthermia, Digestive System Neoplasms

NCT04456140 2023-07-24

Pro-Active Genetic Testing in Patients With Solid Tumors, Inherit Study

BreastCNSGastrointestinalHead & Neck

230 enrolled

Brain Neoplasms, Breast Neoplasms, Digestive System Neoplasms, Head and Neck Neoplasms, Neoplasms, Unknown Primary, Urogenital Neoplasms, Central Nervous System Neoplasms

NCT05281003 2023-07-13

HYPERION

128 enrolled

Parkinson Disease 4, Autosomal Dominant Lewy Body, Esophageal Squamous Cell Carcinoma, Hypoxia, Digestive System Neoplasms, Esophageal Neoplasms, Gastrointestinal Neoplasms, Neoplasms

NCT04962958 2023-06-22

Hepatic Artery Infusion Chemotherapy Plus Donafenib in Patients With Hepatocellular Carcinoma After Surgery

Carcinoma, Digestive System Neoplasms, Carcinoma, Hepatocellular, Liver Neoplasms

NCT05913661 2023-06-22

Pemigatinib Combined With PD-1 Inhibitor in Unresectable or Metastatic Intrahepatic Cholangiocarcinoma

Carcinoma, Digestive System Neoplasms, Cholangiocarcinoma

NCT04163900 2023-05-24

Comparing NUC-1031 Plus Cisplatin to Gemcitabine Plus Cisplatin in Patients With Advanced Biliary Tract Cancer

Phase 3 Terminated

773 enrolled 15 charts

Adenocarcinoma, Biliary Tract Neoplasms, Digestive System Neoplasms, Neoplasm Metastasis, Neoplasms, Cholangiocarcinoma

NCT05673434 2023-01-06

A Clinical Study on the Safety and Efficacy of CAR-T Therapy for the TM4SF1-positive Tumors of Digestive System

Phase NA Unknown

24 enrolled

Digestive System Neoplasms, Neoplasms

NCT05252078 2022-12-16

ALTER-E005

Esophageal Squamous Cell Carcinoma, Carcinoma, Squamous Cell, Digestive System Diseases, Digestive System Neoplasms, Esophageal Diseases, Esophageal Neoplasms, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Squamous Cell

NCT03172403 2022-08-25

MYOCAC

Phase NA Terminated

3 enrolled

Cachexia, Digestive System Neoplasms

NCT04080843 2022-07-13

ALTER-C-002

Phase 2 Completed

Colonic Diseases, Digestive System Diseases, Digestive System Neoplasms, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Intestinal Diseases, Intestinal Neoplasms, Neoplasms, Neoplasms by Site, Rectal Diseases, Colorectal Neoplasms

NCT05238584 2022-05-20

TOPO

Phase NA Unknown

300 enrolled

Digestive System Neoplasms, Stomach Neoplasms

NCT02631590 2021-08-04

Copanlisib (BAY 80-6946) in Combination With Gemcitabine and Cisplatin in Advanced Cholangiocarcinoma

Phase 2 Completed

24 enrolled 11 charts

Digestive System Neoplasms, Gallbladder Neoplasms, Neoplasm Metastasis, Cholangiocarcinoma

NCT04960943 2021-07-14

Efficacy and Safety of Pyrotinib in HER2 Positive Gastrointestinal Tumors

60 enrolled