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Phase

Phase 2 1Phase 1 1

Status

Completed 1

Sponsor Class

NIH 1

Study Type

Interventional 1

Sponsor

Cancer Type

CNS 1

Conditions

Carcinoma, Non-Small-Cell Lung 8Neoplasms 4Lung Neoplasms 4Glioma 4Neoplasm Metastasis 3Glioblastoma 3Colorectal Neoplasms 3Brain Neoplasms 3Pancreatic Neoplasms 2Head and Neck Neoplasms 2Gliosarcoma 2Esophageal Neoplasms 2Carcinoma, Medullary 2Breast Neoplasms 2Adenocarcinoma 2Waldenstrom Macroglobulinemia 1Unspecified Adult Solid Tumor, Protocol Specific 1Thyroid Neoplasms 1Thyroid Carcinoma, Anaplastic 1Thyroid Cancer, Papillary 1Stomach Neoplasms 1Squamous Cell Carcinoma of Head and Neck 1Sezary Syndrome 1Salivary Gland Neoplasms 1Recurrence 1Rectal Neoplasms 1Prostatic Neoplasms 1Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 1Precursor Cell Lymphoblastic Leukemia-Lymphoma 1Pheochromocytoma 1

Interventions

venetoclax 1vandetanib 1tremelimumab 1ricolinostat 1pomalidomide 1pembrolizumab 1pazopanib 1niraparib 1ibrutinib 1enzastaurin 1durvalumab 1copanlisib 1brigatinib 1binimetinib 1avasopasem manganese 1abexinostat 1Transplantation, Autologous 1Steroids 1Melphalan 1Interleukin-2 1Granulocyte Colony-Stimulating Factor 1Filgrastim 1Dexamethasone 1Blood Specimen Collection 1Biopsy 1AZD 6244 1

Date Range

30 days90 days1 yearAll

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Clinical Trials

1 trials
RecentStart dateEnrollment
Phase 1 × Disease Progression × vandetanib × Clear all
NCT00272350 2019-12-05

ZD6474 to Treat Advanced Brain Cancer in Patients

National Institutes of Health Clinical Center (CC)

Phase 1 Completed
83 enrolled
CNS

Brain Neoplasms, Glioma, Neoplasms, Disease Progression

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