Announcements Trials
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Phase

Phase 2 1Phase 1 1

Status

Completed 2

Sponsor Class

NIH 2

Study Type

Interventional 2

Sponsor

Cancer Type

CNS 2Sarcoma 1

Conditions

Neoplasms 3Carcinoma, Renal Cell 3Kidney Neoplasms 2Glioma 2Disease Progression 2Carcinoma, Medullary 2Brain Neoplasms 2Waldenstrom Macroglobulinemia 1Thyroid Neoplasms 1Sezary Syndrome 1Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 1Precursor Cell Lymphoblastic Leukemia-Lymphoma 1Peritoneal Neoplasms 1Ovarian Neoplasms 1Oligodendroglioma 1Mycosis Fungoides 1Multiple Endocrine Neoplasia Type 2b 1Multiple Endocrine Neoplasia Type 2a 1Multiple Endocrine Neoplasia 1Lymphoproliferative Disorders 1Lymphoma, T-Cell, Cutaneous 1Lymphoma, Non-Hodgkin 1Lymphoma, Mantle-Cell 1Lymphoma, Large-Cell, Immunoblastic 1Lymphoma, Large-Cell, Anaplastic 1Lymphoma, Large B-Cell, Diffuse 1Lymphoma, Follicular 1Lymphoma, Extranodal NK-T-Cell 1Lymphoma, B-Cell, Marginal Zone 1Lymphoma 1

Interventions

vandetanib 2Lenalidomide 2Bortezomib 2marizomib 1enzastaurin 1carotuximab 1Tamoxifen 1Steroids 1Multiparametric Magnetic Resonance Imaging 1Irinotecan 1Dexamethasone 1Carboplatin 1Calcium Dobesilate 1Bevacizumab 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
NIH × Disease Progression × vandetanib × Clear all
NCT00272350 2019-12-05

ZD6474 to Treat Advanced Brain Cancer in Patients

National Institutes of Health Clinical Center (CC)

Phase 1 Completed
83 enrolled
CNS

Brain Neoplasms, Glioma, Neoplasms, Disease Progression

NCT00995007 2016-03-29

A Randomized Phase II Trial of Vandetanib (ZD6474) in Combination With Carboplatin Versus Carboplatin Alone Followed by Vandetanib Alone in Adults With Recurrent High-Grade Gliomas

National Institutes of Health Clinical Center (CC)

Phase 2 Completed
112 enrolled 12 charts
CNSSarcoma

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma, Gliosarcoma, Disease Progression

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