Announcements Trials
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Phase

Phase 3 2Phase 2 1

Status

Active not recruiting 2Completed 1

Sponsor Class

OTHER 1NIH 1NETWORK 1

Study Type

Interventional 3

Sponsor

Cancer Type

Other hematologic neoplasm 3Lymphoid 3

Conditions

Burkitt Lymphoma 15Precursor Cell Lymphoblastic Leukemia-Lymphoma 12Leukemia, Biphenotypic, Acute 6Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 4Precursor B-Cell Lymphoblastic Leukemia-Lymphoma 4Leukemia, Myeloid, Acute 4Lymphoma, Mantle-Cell 3Leukemia, Myeloid, Accelerated Phase 3Down Syndrome 3Blast Crisis 3Osteosarcoma 2Myeloproliferative Disorders 2Leukemia 2Blastic Plasmacytoid Dendritic Cell Neoplasm 2Anemia, Refractory, with Excess of Blasts 2Waldenstrom Macroglobulinemia 1Urothelial Carcinoma of the Bladder 1Thrombocythemia, Essential 1Sezary Syndrome 1Sarcoma, Ewing 1Rhabdoid Tumor 1Renal Pelvis and Ureter Urothelial Carcinoma 1Recurrence 1Primary Myelofibrosis 1Precancerous Conditions 1Polycythemia Vera 1Pdgfra-Associated Chronic Eosinophilic Leukemia 1Oropharyngeal Neoplasms 1Neoplasms, Plasma Cell 1Neoplasms 1

Interventions

Vincristine 3Methotrexate 3Mercaptopurine 3Cytarabine 3Cyclophosphamide 3prednylidene 2pegaspargase 2merphos 2dexamethasone acetate 2dexamethasone 21-phosphate 2azathiopurine 2auricularum 2Thioguanine 2Prednisolone 2Leucovorin 2Doxorubicin 2Dexamethasone 2Calcium Dobesilate 2deltacortene 1blinatumomab 1asparaginase erwinia chrysanthemi recombinant 1Radiotherapy 1Radiation 1Prednisone 1N,N-dicyclohexyl-isoborneol-10-sulfonamide 1Methylprednisolone 1Hydrocortisone 1Epirubicin 1Daunorubicin 1Asparaginase 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Down Syndrome × Methotrexate × 30 days × Clear all
NCT01190930 2026-05-28

Risk-Adapted Chemotherapy in Treating Younger Patients With Newly Diagnosed Standard-Risk Acute Lymphoblastic Leukemia or Localized B-Lineage Lymphoblastic Lymphoma

Children's Oncology Group

Phase 3 Completed
9,350 enrolled 51 charts
LymphoidOther hematologic neoplasm

Down Syndrome, Precursor B-Cell Lymphoblastic Leukemia-Lymphoma, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT03914625 2026-05-27

A Study to Investigate Blinatumomab in Combination With Chemotherapy in Patients With Newly Diagnosed B-Lymphoblastic Leukemia

National Cancer Institute (NCI)

Phase 3 Active not recruiting
6,720 enrolled
LymphoidOther hematologic neoplasm

Burkitt Lymphoma, Down Syndrome, Precursor B-Cell Lymphoblastic Leukemia-Lymphoma

NCT03286634 2026-05-11

ASIA Down Syndrome Acute Lymphoblastic Leukemia 2016

National Hospital Organization Nagoya Medical Center

Phase 2 Active not recruiting
60 enrolled
LymphoidOther hematologic neoplasm

Down Syndrome, Neoplasms, Precursor Cell Lymphoblastic Leukemia-Lymphoma

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