Announcements Trials
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Phase

Phase 3 2Phase 2 1

Status

Recruiting 1Completed 1Active not recruiting 1

Sponsor Class

NIH 2NETWORK 1

Study Type

Interventional 3

Sponsor

Cancer Type

Lymphoid 3Other hematologic neoplasm 2

Conditions

Burkitt Lymphoma 9Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 3Precursor Cell Lymphoblastic Leukemia-Lymphoma 3Precursor B-Cell Lymphoblastic Leukemia-Lymphoma 3Multiple Myeloma 3Down Syndrome 3Lymphoma, Mantle-Cell 2Lung Neoplasms 2Leukemia, Biphenotypic, Acute 2Smoldering Multiple Myeloma 1Neoplasms 1Leukemia, Plasma Cell 1Immunoglobulin Light-chain Amyloidosis 1Esophageal Neoplasms 1Dyspnea 1Carcinoma, Non-Small-Cell Lung 1

Interventions

pegaspargase 3merphos 3dexamethasone acetate 3dexamethasone 21-phosphate 3azathiopurine 3auricularum 3Vincristine 3Methotrexate 3Mercaptopurine 3Dexamethasone 3Cytarabine 3Calcium Dobesilate 3blinatumomab 2asparaginase erwinia chrysanthemi recombinant 2Thioguanine 2N,N-dicyclohexyl-isoborneol-10-sulfonamide 2Leucovorin 2Doxorubicin 2Cyclophosphamide 2Asparaginase 2prednylidene 1hydrocortisone hemisuccinate 1deltacortene 1calaspargase pegol 1Spinal Puncture 1Specimen Handling 1Radiotherapy, Conformal 1Radiotherapy 1Radiation 1Prednisone 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Down Syndrome × dexamethasone acetate × 30 days × Clear all
NCT04546399 2026-06-12

A Study to Compare Blinatumomab Alone to Blinatumomab With Nivolumab in Patients Diagnosed With First Relapse B-Cell Acute Lymphoblastic Leukemia (B-ALL)

National Cancer Institute (NCI)

Phase 2 Recruiting
461 enrolled
Lymphoid

Burkitt Lymphoma, Down Syndrome

NCT01190930 2026-05-28

Risk-Adapted Chemotherapy in Treating Younger Patients With Newly Diagnosed Standard-Risk Acute Lymphoblastic Leukemia or Localized B-Lineage Lymphoblastic Lymphoma

Children's Oncology Group

Phase 3 Completed
9,350 enrolled 51 charts
LymphoidOther hematologic neoplasm

Down Syndrome, Precursor B-Cell Lymphoblastic Leukemia-Lymphoma, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT03914625 2026-05-27

A Study to Investigate Blinatumomab in Combination With Chemotherapy in Patients With Newly Diagnosed B-Lymphoblastic Leukemia

National Cancer Institute (NCI)

Phase 3 Active not recruiting
6,720 enrolled
LymphoidOther hematologic neoplasm

Burkitt Lymphoma, Down Syndrome, Precursor B-Cell Lymphoblastic Leukemia-Lymphoma

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