Announcements Trials
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Phase

Phase 3 2

Status

Completed 1Active not recruiting 1

Sponsor Class

NETWORK 2

Study Type

Interventional 2

Sponsor

Cancer Type

Other hematologic neoplasm 2Myeloid 1Lymphoid 1

Conditions

Leukemia, Myeloid, Acute 167Leukemia 86Precursor Cell Lymphoblastic Leukemia-Lymphoma 71Lymphoma 51Myelodysplastic Syndromes 38Congenital Abnormalities 32Burkitt Lymphoma 29Lymphoma, Non-Hodgkin 27Recurrence 26Leukemia, Myelomonocytic, Acute 26Leukemia, Monocytic, Acute 26Lymphoma, Mantle-Cell 23Leukemia, Erythroblastic, Acute 23Leukemia, Megakaryoblastic, Acute 21Hodgkin Disease 18Lymphoma, Large B-Cell, Diffuse 17Lymphoma, Follicular 13Myeloproliferative Disorders 12Leukemia, Myelomonocytic, Chronic 11Leukemia, Biphenotypic, Acute 11Leukemia, Eosinophilic, Acute 9Blast Crisis 9Lymphoma, B-Cell 8Leukemia, Myelogenous, Chronic, BCR-ABL Positive 8Anemia, Refractory, with Excess of Blasts 8Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 7Neoplasms 7Multiple Myeloma 7Leukemia, Basophilic, Acute 7Leukemia, Lymphocytic, Chronic, B-Cell 6

Interventions

Thioguanine 2Cytarabine 2pegaspargase 1merphos 1dexamethasone acetate 1dexamethasone 21-phosphate 1azathiopurine 1auricularum 1asparaginase erwinia chrysanthemi recombinant 1Vincristine 1Mitoxantrone 1Methotrexate 1Mercaptopurine 1Leyk 1Leucovorin 1Etoposide 1Doxorubicin 1Dexamethasone 1Daunorubicin 1Cyclophosphamide 1Calcium Dobesilate 1Asparaginase 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Has results × Down Syndrome × Cytarabine × Clear all
NCT01190930 2026-05-28

Risk-Adapted Chemotherapy in Treating Younger Patients With Newly Diagnosed Standard-Risk Acute Lymphoblastic Leukemia or Localized B-Lineage Lymphoblastic Lymphoma

Children's Oncology Group

Phase 3 Completed
9,350 enrolled 51 charts
LymphoidOther hematologic neoplasm

Down Syndrome, Precursor B-Cell Lymphoblastic Leukemia-Lymphoma, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT02521493 2025-08-01

Response-Based Chemotherapy in Treating Newly Diagnosed Acute Myeloid Leukemia or Myelodysplastic Syndrome in Younger Patients With Down Syndrome

Children's Oncology Group

Phase 3 Active not recruiting
280 enrolled 13 charts
MyeloidOther hematologic neoplasm

Down Syndrome, Myelodysplastic Syndromes, Myeloproliferative Disorders, Leukemia, Myeloid, Acute

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