Announcements Trials
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Phase

Phase 3 4Phase 2 2

Status

Active not recruiting 2Recruiting 1Completed 1

Sponsor Class

NETWORK 2OTHER 1NIH 1

Study Type

Interventional 4

Sponsor

Cancer Type

Other hematologic neoplasm 4Lymphoid 2Myeloid 1

Conditions

Leukemia, Myeloid, Acute 89Leukemia 68Precursor Cell Lymphoblastic Leukemia-Lymphoma 36Lymphoma 26Leukemia, Erythroblastic, Acute 19Leukemia, Myelomonocytic, Acute 18Leukemia, Monocytic, Acute 18Leukemia, Megakaryoblastic, Acute 18Congenital Abnormalities 13Burkitt Lymphoma 13Lymphoma, Large B-Cell, Diffuse 12Myelodysplastic Syndromes 10Lymphoma, Non-Hodgkin 10Anemia, Refractory, with Excess of Blasts 9Leukemia, Myelogenous, Chronic, BCR-ABL Positive 8Lymphoma, Follicular 6Leukemia, Myelomonocytic, Chronic 6Leukemia, Myeloid, Chronic-Phase 6Leukemia, Eosinophilic, Acute 6Recurrence 5Myeloproliferative Disorders 5Lymphoma, Large-Cell, Immunoblastic 5Leukemia, Promyelocytic, Acute 5Leukemia, Biphenotypic, Acute 5Leukemia, Basophilic, Acute 5Hodgkin Disease 5Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 4Neoplasms 4Myelodysplastic-Myeloproliferative Diseases 4Multiple Myeloma 4

Interventions

Cytarabine 4Thioguanine 3pegaspargase 2merphos 2dexamethasone acetate 2dexamethasone 21-phosphate 2azathiopurine 2auricularum 2asparaginase erwinia chrysanthemi recombinant 2Vincristine 2Methotrexate 2Mercaptopurine 2Leucovorin 2Etoposide 2Doxorubicin 2Dexamethasone 2Daunorubicin 2Cyclophosphamide 2Calcium Dobesilate 2Asparaginase 2prednylidene 1deltacortene 1blinatumomab 1Radiotherapy 1Radiation 1Prednisone 1Prednisolone 1N,N-dicyclohexyl-isoborneol-10-sulfonamide 1Mitoxantrone 1Methylprednisolone 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
Phase 3 × Down Syndrome × Cytarabine × Clear all
NCT01190930 2026-05-28

Risk-Adapted Chemotherapy in Treating Younger Patients With Newly Diagnosed Standard-Risk Acute Lymphoblastic Leukemia or Localized B-Lineage Lymphoblastic Lymphoma

Children's Oncology Group

Phase 3 Completed
9,350 enrolled 51 charts
LymphoidOther hematologic neoplasm

Down Syndrome, Precursor B-Cell Lymphoblastic Leukemia-Lymphoma, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT03914625 2026-05-27

A Study to Investigate Blinatumomab in Combination With Chemotherapy in Patients With Newly Diagnosed B-Lymphoblastic Leukemia

National Cancer Institute (NCI)

Phase 3 Active not recruiting
6,720 enrolled
LymphoidOther hematologic neoplasm

Burkitt Lymphoma, Down Syndrome, Precursor B-Cell Lymphoblastic Leukemia-Lymphoma

NCT07232134 2025-11-20

AML-DS-2025

Federal Research Institute of Pediatric Hematology, Oncology and Immunology

Phase 3 Recruiting
100 enrolled
Other hematologic neoplasm

Down Syndrome, Leukemia, Myeloid, Acute

NCT02521493 2025-08-01

Response-Based Chemotherapy in Treating Newly Diagnosed Acute Myeloid Leukemia or Myelodysplastic Syndrome in Younger Patients With Down Syndrome

Children's Oncology Group

Phase 3 Active not recruiting
280 enrolled 13 charts
MyeloidOther hematologic neoplasm

Down Syndrome, Myelodysplastic Syndromes, Myeloproliferative Disorders, Leukemia, Myeloid, Acute

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