Announcements Trials
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Phase

Phase 3 1

Status

Active not recruiting 1

Sponsor Class

NETWORK 1

Study Type

Interventional 1

Sponsor

Cancer Type

Other hematologic neoplasm 1Myeloid 1

Conditions

Leukemia, Myeloid, Acute 22Leukemia 15Lymphoma 11Leukemia, Erythroblastic, Acute 8Prostatic Neoplasms 7Leukemia, Myelomonocytic, Acute 7Leukemia, Monocytic, Acute 7Leukemia, Megakaryoblastic, Acute 7Precursor Cell Lymphoblastic Leukemia-Lymphoma 6Lymphoma, Large B-Cell, Diffuse 6Lymphoma, Follicular 6Myelodysplastic Syndromes 5Lymphoma, Non-Hodgkin 5Lymphoma, Large-Cell, Immunoblastic 5Anemia, Refractory, with Excess of Blasts 4Leukemia, Promyelocytic, Acute 3Congenital Abnormalities 3Breast Neoplasms 3Pain 2Neutropenia 2Myeloproliferative Disorders 2Leukemia, Myelomonocytic, Chronic 2Burkitt Lymphoma 2Sarcoma, Myeloid 1Recurrence 1Ovarian Neoplasms 1Neoplasms 1Neoplasm, Residual 1Myelodysplastic-Myeloproliferative Diseases 1Lymphoma, Large-Cell, Anaplastic 1

Interventions

Cytarabine 4Thioguanine 3pegaspargase 2merphos 2dexamethasone acetate 2dexamethasone 21-phosphate 2azathiopurine 2auricularum 2asparaginase erwinia chrysanthemi recombinant 2Vincristine 2Methotrexate 2Mercaptopurine 2Leucovorin 2Etoposide 2Doxorubicin 2Dexamethasone 2Daunorubicin 2Cyclophosphamide 2Calcium Dobesilate 2Asparaginase 2prednylidene 1deltacortene 1blinatumomab 1Radiotherapy 1Radiation 1Prednisone 1Prednisolone 1N,N-dicyclohexyl-isoborneol-10-sulfonamide 1Mitoxantrone 1Methylprednisolone 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Phase 3 × Down Syndrome × Mitoxantrone × Clear all
NCT02521493 2025-08-01

Response-Based Chemotherapy in Treating Newly Diagnosed Acute Myeloid Leukemia or Myelodysplastic Syndrome in Younger Patients With Down Syndrome

Children's Oncology Group

Phase 3 Active not recruiting
280 enrolled 13 charts
MyeloidOther hematologic neoplasm

Down Syndrome, Myelodysplastic Syndromes, Myeloproliferative Disorders, Leukemia, Myeloid, Acute

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