Announcements Trials
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Phase

Phase 3 1Phase 2/3 1Phase 1/2 1

Status

Unknown 2Withdrawn 1Completed 1

Sponsor Class

OTHER 4

Study Type

Interventional 3Observational 1

Sponsor

Cancer Type

Other hematologic neoplasm 2Sarcoma 1Lymphoid 1Gynecologic 1Genitourinary 1CNS 1Breast 1

Conditions

Precursor Cell Lymphoblastic Leukemia-Lymphoma 250Leukemia 186Lymphoma 137Leukemia, Myeloid, Acute 103Burkitt Lymphoma 90Myelodysplastic Syndromes 79Lymphoma, Non-Hodgkin 65Breast Neoplasms 60Lymphoma, Large B-Cell, Diffuse 59Leukemia, Lymphocytic, Chronic, B-Cell 49Lymphoma, Mantle-Cell 47Hodgkin Disease 47Graft vs Host Disease 46Lymphoma, Follicular 45Leukemia, Myeloid, Accelerated Phase 45Multiple Myeloma 39Leukemia, Myeloid, Chronic-Phase 39Congenital Abnormalities 39Myeloproliferative Disorders 38Blast Crisis 38Leukemia, Myelomonocytic, Chronic 37Leukemia, Biphenotypic, Acute 35Recurrence 34Lymphoma, Large-Cell, Immunoblastic 33Lymphoma, B-Cell, Marginal Zone 31Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 30Osteosarcoma 29Primary Myelofibrosis 27Neoplasms, Plasma Cell 25Leukemia, Myelogenous, Chronic, BCR-ABL Positive 25

Interventions

Amifostine 19Cisplatin 15Radiotherapy 13Etoposide 10Cyclophosphamide 9Carboplatin 8Paclitaxel 7Filgrastim 7Drug Therapy 5Cytarabine 5apatinib 4Methotrexate 4sodium thiosulfate 3Methylprednisolone 3Gemcitabine 3Docetaxel 3sargramostim 2pegfilgrastim 2glucarpidase 2etoposide phosphate 2denileukin diftitox 2camrelizumab 2Voriconazole 2Vincristine 2Social Determinants of Health 2Pyridoxine 2Peripheral Blood Stem Cell Transplantation 2Nivolumab 2Mitoxantrone 2Melphalan 2

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
Drug-Related Side Effects and Adverse Reactions × Methotrexate × Clear all
NCT00400946 2026-02-13

05-001: Treatment of Acute Lymphoblastic Leukemia in Children

Dana-Farber Cancer Institute

Phase 3 Completed
800 enrolled 22 charts
LymphoidOther hematologic neoplasm

Leukemia, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Drug-Related Side Effects and Adverse Reactions

NCT05899751 2024-05-10

Retrospective Registry Study of Patients With Cancer Treated With High-dose Methotrexate

BTG International Inc.

Unknown
1,000 enrolled
GenitourinaryOther hematologic neoplasmSarcoma

Osteosarcoma, Water Intoxication, Hematologic Neoplasms, Acute Kidney Injury, Drug-Related Side Effects and Adverse Reactions

NCT03885388 2019-03-21

Combination of Methotrexate(MTX) and Actinomycin(ACTD) in the Low Risk Gestational Trophoblastic Neoplasma (GTN) Patients With Score of 5-6

Women's Hospital School Of Medicine Zhejiang University

Phase 2/3 Unknown
300 enrolled
Gynecologic

Gestational Trophoblastic Disease, Drug-Related Side Effects and Adverse Reactions

NCT00397501 2017-04-21

BBBD Followed By Methotrexate and Carboplatin With or Without Trastuzumab in Treating Women With Breast Cancer That Has Spread to the Brain

OHSU Knight Cancer Institute

Phase 1/2 Withdrawn
BreastCNS

Brain Neoplasms, Breast Neoplasms, Central Nervous System Neoplasms, Drug-Related Side Effects and Adverse Reactions

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