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Phase

Phase 3 1Phase 2/3 1Phase 1/2 1

Status

Unknown 2Withdrawn 1Completed 1

Sponsor Class

OTHER 4

Study Type

Interventional 3Observational 1

Sponsor

Cancer Type

Other hematologic neoplasm 2Sarcoma 1Lymphoid 1Gynecologic 1Genitourinary 1CNS 1Breast 1

Conditions

Precursor Cell Lymphoblastic Leukemia-Lymphoma 182Leukemia 128Lymphoma 91Leukemia, Myeloid, Acute 83Myelodysplastic Syndromes 64Burkitt Lymphoma 59Lymphoma, Non-Hodgkin 53Lymphoma, Large B-Cell, Diffuse 42Leukemia, Myeloid, Accelerated Phase 39Leukemia, Lymphocytic, Chronic, B-Cell 39Lymphoma, Mantle-Cell 38Hodgkin Disease 38Graft vs Host Disease 36Blast Crisis 35Congenital Abnormalities 34Multiple Myeloma 33Lymphoma, Follicular 33Leukemia, Myeloid, Chronic-Phase 33Myeloproliferative Disorders 32Recurrence 30Breast Neoplasms 29Leukemia, Myelomonocytic, Chronic 28Primary Myelofibrosis 26Lymphoma, Large-Cell, Immunoblastic 26Lymphoma, B-Cell, Marginal Zone 25Neoplasms, Plasma Cell 22Osteosarcoma 21Leukemia, Myelogenous, Chronic, BCR-ABL Positive 21Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 20Leukemia, Biphenotypic, Acute 20

Interventions

Cisplatin 7Etoposide 6Amifostine 6Radiotherapy 5Drug Therapy 5Cyclophosphamide 5apatinib 4Methotrexate 4Filgrastim 4Cytarabine 4sodium thiosulfate 3Methylprednisolone 3Carboplatin 3pegfilgrastim 2glucarpidase 2etoposide phosphate 2Voriconazole 2Vincristine 2Social Determinants of Health 2Pyridoxine 2Nivolumab 2Gemcitabine 2Doxorubicin 2Docetaxel 2Chemotherapy, Adjuvant 2Capecitabine 2trastuzumab deruxtecan 1selinexor 1sargramostim 1sacituzumab govitecan 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
OTHER × Drug-Related Side Effects and Adverse Reactions × Methotrexate × Clear all
NCT00400946 2026-02-13

05-001: Treatment of Acute Lymphoblastic Leukemia in Children

Dana-Farber Cancer Institute

Phase 3 Completed
800 enrolled 22 charts
LymphoidOther hematologic neoplasm

Leukemia, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Drug-Related Side Effects and Adverse Reactions

NCT05899751 2024-05-10

Retrospective Registry Study of Patients With Cancer Treated With High-dose Methotrexate

BTG International Inc.

Unknown
1,000 enrolled
GenitourinaryOther hematologic neoplasmSarcoma

Osteosarcoma, Water Intoxication, Hematologic Neoplasms, Acute Kidney Injury, Drug-Related Side Effects and Adverse Reactions

NCT03885388 2019-03-21

Combination of Methotrexate(MTX) and Actinomycin(ACTD) in the Low Risk Gestational Trophoblastic Neoplasma (GTN) Patients With Score of 5-6

Women's Hospital School Of Medicine Zhejiang University

Phase 2/3 Unknown
300 enrolled
Gynecologic

Gestational Trophoblastic Disease, Drug-Related Side Effects and Adverse Reactions

NCT00397501 2017-04-21

BBBD Followed By Methotrexate and Carboplatin With or Without Trastuzumab in Treating Women With Breast Cancer That Has Spread to the Brain

OHSU Knight Cancer Institute

Phase 1/2 Withdrawn
BreastCNS

Brain Neoplasms, Breast Neoplasms, Central Nervous System Neoplasms, Drug-Related Side Effects and Adverse Reactions

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