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Phase

Phase 1 2Phase NA 1Phase 1/2 1

Status

Completed 74Recruiting 53Terminated 28Active not recruiting 26Unknown 9Withdrawn 6Not yet recruiting 3Suspended 2

Sponsor Class

OTHER 1INDUSTRY 1

Study Type

Interventional 2

Sponsor

Cancer Type

Gynecologic 2Gastrointestinal 2Thoracic 1Sarcoma 1Head & Neck 1Genitourinary 1Breast 1

Conditions

Neoplasms 12Leukemia, Myeloid, Acute 12Neoplasm Metastasis 9Melanoma 7Breast Neoplasms 7Prostatic Neoplasms 6Pancreatic Neoplasms 6Ovarian Neoplasms 6Colorectal Neoplasms 6Precursor Cell Lymphoblastic Leukemia-Lymphoma 5Myelodysplastic Syndromes 5Lung Neoplasms 5Glioma 5Hematologic Neoplasms 4Glioblastoma 4Triple Negative Breast Neoplasms 3Stomach Neoplasms 3Solid Tumors 3Small Cell Lung Carcinoma 3Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 3Lymphoma 3Head and Neck Neoplasms 3Carcinoma, Renal Cell 3Carcinoma, Non-Small-Cell Lung 3Unspecified Adult Solid Tumor, Protocol Specific 2Solid Tumor 2Sarcoma 2Osteosarcoma 2Lymphoma, T-Cell, Peripheral 2Lymphoma, B-Cell 2

Interventions

palbociclib 1gedatolisib 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Phase 1 × Suspended × Endometrial Neoplasms × Clear all
NCT03065062 2026-02-13

Study of the CDK4/6 Inhibitor Palbociclib (PD-0332991) in Combination With the PI3K/mTOR Inhibitor Gedatolisib (PF-05212384) for Patients With Advanced Squamous Cell Lung, Pancreatic, Head & Neck and Other Solid Tumors

Dana-Farber Cancer Institute

Phase 1 Suspended
75 enrolled
GastrointestinalGynecologicHead & Neck

Head and Neck Neoplasms, Neoplasms, Pancreatic Neoplasms, Endometrial Neoplasms

NCT05958199 2025-06-27

A Study of NPX267 for Subjects With Solid Tumors Known to Express HHLA2/B7-H7

NextPoint Therapeutics, Inc.

Phase 1 Suspended
131 enrolled
BreastGastrointestinalGenitourinaryGynecologicSarcomaThoracic

Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Transitional Cell, Uterine Cervical Neoplasms, Neoplasm Metastasis, Pancreatic Neoplasms, Prostatic Neoplasms, Osteosarcoma, Colorectal Neoplasms, Endometrial Neoplasms, Cholangiocarcinoma, Triple Negative Breast Neoplasms

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