Clinical Trials Browser

Ependymoma, Medulloblastoma

NCT03911388 2026-04-13

HSV G207 in Children With Recurrent or Refractory Cerebellar Brain Tumors

Choroid Plexus Carcinoma, Astrocytoma, Brain Diseases, Brain Neoplasms, Central Nervous System Diseases, Cerebellar Neoplasms, Ependymoma, Glioblastoma, Glioma, Medulloblastoma, Neoplasm Metastasis, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Glandular and Epithelial, Neoplasms, Nerve Tissue, Nervous System Diseases, Nervous System Neoplasms, Oligodendroglioma, Virus Diseases, Central Nervous System Neoplasms, Neuroectodermal Tumors, Neuroectodermal Tumors, Primitive, Neoplasms, Neuroepithelial, Gliosarcoma, Rhabdoid Tumor

NCT04185038 2026-04-13

Study of B7-H3-Specific CAR T Cell Locoregional Immunotherapy for Diffuse Intrinsic Pontine Glioma/Diffuse Midline Glioma and Recurrent or Refractory Pediatric Central Nervous System Tumors

Phase 1 Recruiting

90 enrolled

CNS

Choroid Plexus Carcinoma, Diffuse Intrinsic Pontine Glioma, Brain Neoplasms, Ependymoma, Glioma, Medulloblastoma, Neoplasms, Germ Cell and Embryonal, Pinealoma, Central Nervous System Neoplasms, Neuroectodermal Tumors, Primitive, Rhabdoid Tumor

NCT05278208 2026-04-13

Lutathera for Treatment of Recurrent or Progressive High-Grade CNS Tumors

Phase 1/2 Recruiting

65 enrolled

CNS

Diffuse Intrinsic Pontine Glioma, Ependymoma, Glioma, Medulloblastoma, Meningioma, Neoplasms, Germ Cell and Embryonal, Central Nervous System Neoplasms

NCT04732065 2026-03-17

PNOC023

Phase 1 Recruiting

208 enrolled

CNS

Ependymoma, Glioblastoma, Central Nervous System Neoplasms

NCT06193759 2026-03-10

IMPACT

Phase 1 Recruiting

12 enrolled

CNS

Ependymoma, Medulloblastoma, Pinealoma, Neuroectodermal Tumors, Primitive, Rhabdoid Tumor

NCT06639607 2026-03-10

PRiME II

Phase 1/2 Not yet recruiting

68 enrolled

CNS

Diffuse Intrinsic Pontine Glioma, Ependymoma, Medulloblastoma, Recurrence

NCT04661384 2026-03-05

Brain Tumor-Specific Immune Cells (IL13Ralpha2-CAR T Cells) for the Treatment of Leptomeningeal Glioblastoma, Ependymoma, or Medulloblastoma

Phase 1 Active not recruiting

10 enrolled

CNS

Ependymoma, Glioblastoma, Medulloblastoma, Meningeal Carcinomatosis

NCT03152318 2026-03-04

rQNestin

Phase 1 Active not recruiting

62 enrolled

CNS

Astrocytoma, Brain Neoplasms, Disease, Ependymoma, Glioblastoma, Glioma, Oligodendroglioma, Ganglioglioma

NCT02574728 2026-03-02

AflacST1502

Phase 2 Active not recruiting

46 enrolled

CNSMyeloidSarcoma

Brain Neoplasms, Carcinoma, Ependymoma, Histiocytosis, Langerhans-Cell, Medulloblastoma, Neoplasms, Neoplasms, Germ Cell and Embryonal, Neuroblastoma, Pinealoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Rhabdoid Tumor

NCT02125786 2026-02-24

A Trial of Surgery and Fractionated Re-Irradiation for Recurrent Ependymoma

Phase 2 Active not recruiting

68 enrolled 11 charts

Ependymoma

NCT01356290 2026-02-23

MEMMAT

Phase 2 Recruiting

232 enrolled

CNS

Ependymoma, Medulloblastoma, Recurrence

NCT07424092 2026-02-20

PED-DNX2401

Phase 2 Not yet recruiting

39 enrolled

CNS

Ependymoma, Glioma, Recurrence

NCT05957679 2026-02-12

MRE Evaluation for Spinal Cord Tumor Surgery: Stiffness and Adhesion Assessment

Phase NA Recruiting

20 enrolled

CNS

Astrocytoma, Ependymoma, Glioblastoma, Glioma, Meningioma, Neurofibroma, Spinal Cord Neoplasms

NCT01795313 2026-02-05

Immunotherapy for Recurrent Ependymomas in Children Using Tumor Antigen Peptides With Imiquimod

Phase 1 Terminated

23 enrolled

Ependymoma

NCT07390539 2026-02-05

B7-H3.CD28Z.CART in CNS Neoplasms

Phase 1 Not yet recruiting

70 enrolled

CNS

Brain Neoplasms, Ependymoma, Medulloblastoma, Meningeal Neoplasms, Pinealoma, Central Nervous System Neoplasms, Neuroectodermal Tumors, Primitive, Rhabdoid Tumor

NCT00840047 2026-01-20

Methionine PET/CT Studies In Patients With Cancer

Phase 2 Active not recruiting

503 enrolled

CNSLymphoidSarcoma

Craniopharyngioma, Ependymoma, Hodgkin Disease, Lymphoma, Non-Hodgkin, Medulloblastoma, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Ewing, Osteosarcoma

NCT05835687 2026-01-20

Loc3CAR: Locoregional Delivery of B7-H3-CAR T Cells for Pediatric Patients With Primary CNS Tumors

Phase 1 Recruiting

48 enrolled

CNS

Ependymoma, Glioblastoma, Glioma, Medulloblastoma, Central Nervous System Neoplasms, Rhabdoid Tumor

Clinical Trials

PNOC027

HSV G207 in Children With Recurrent or Refractory Cerebellar Brain Tumors

Study of B7-H3-Specific CAR T Cell Locoregional Immunotherapy for Diffuse Intrinsic Pontine Glioma/Diffuse Midline Glioma and Recurrent or Refractory Pediatric Central Nervous System Tumors

Lutathera for Treatment of Recurrent or Progressive High-Grade CNS Tumors

PNOC023

IMPACT

PRiME II

Brain Tumor-Specific Immune Cells (IL13Ralpha2-CAR T Cells) for the Treatment of Leptomeningeal Glioblastoma, Ependymoma, or Medulloblastoma

rQNestin

AflacST1502

A Trial of Surgery and Fractionated Re-Irradiation for Recurrent Ependymoma

MEMMAT

PED-DNX2401

MRE Evaluation for Spinal Cord Tumor Surgery: Stiffness and Adhesion Assessment

Immunotherapy for Recurrent Ependymomas in Children Using Tumor Antigen Peptides With Imiquimod

B7-H3.CD28Z.CART in CNS Neoplasms

Methionine PET/CT Studies In Patients With Cancer

Loc3CAR: Locoregional Delivery of B7-H3-CAR T Cells for Pediatric Patients With Primary CNS Tumors