Announcements Trials
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Phase

Phase 1 3Phase EARLY_PHASE1 1

Status

Completed 2Withdrawn 1

Sponsor Class

OTHER 3

Study Type

Interventional 3

Sponsor

Cancer Type

CNS 2

Conditions

Leukemia, Myeloid, Acute 99Myelodysplastic Syndromes 56Leukemia, Myelomonocytic, Chronic 23Leukemia 17Recurrence 10Precursor Cell Lymphoblastic Leukemia-Lymphoma 10Lymphoma, Non-Hodgkin 10Hematologic Neoplasms 9Multiple Myeloma 8Hodgkin Disease 8Neoplasms 6Myeloproliferative Disorders 6Leukemia, Myeloid 6Leukemia, Lymphocytic, Chronic, B-Cell 6Carcinoma, Non-Small-Cell Lung 6Myelodysplastic-Myeloproliferative Diseases 5Lymphoma 5Leukemia, Myelogenous, Chronic, BCR-ABL Positive 5Sarcoma 4Primary Myelofibrosis 4Ovarian Neoplasms 4Lymphoma, Large B-Cell, Diffuse 4Lymphoma, Follicular 4Leukemia, Biphenotypic, Acute 4Head and Neck Neoplasms 4Anemia, Refractory, with Excess of Blasts 4Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 3Neoplasm Metastasis 3Melanoma 3Lymphoma, T-Cell, Peripheral 3

Interventions

Temozolomide 11Filgrastim 5Magnetic Resonance Spectroscopy 4Cyclophosphamide 4Carmustine 4Thiotepa 3Radiation 3Etoposide 3Carboplatin 3Azacitidine 3Automobiles 3sargramostim 2Radiotherapy 2Peripheral Blood Stem Cell Transplantation 2ONC206 2O(6)-benzylguanine 2Nivolumab 2Melphalan 2Immunohistochemistry 2Imiquimod 2Imatinib Mesylate 2Granulocyte Colony-Stimulating Factor 22-phenyl-6-(2'-(4'-(ethoxycarbonyl)thiazolyl))thiazolo(3,2-b)(1,2,4)triazole 22,2-dimethyl-N-(6-oxo-6,7-dihydro-5H-dibenzo(b,d)azepin-7-yl)-N'-(2,2,3,3,3-pentafluoropropyl)malonamide 21-methyltryptophan 2vitespin 1veliparib 1vatalanib 1trametinib 1thymoglobulin 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Phase 1 × Ependymoma × Azacitidine × Clear all
NCT06466798 2026-01-08

Fourth Ventricular Administration of Immune Checkpoint Inhibitor (Nivolumab) and Methotrexate or 5-Azacytidine for Recurrent Medulloblastoma, Ependymoma, and Other CNS Malignancies

The University of Texas Health Science Center, Houston

Phase 1 Withdrawn
CNS

Ependymoma, Medulloblastoma, Central Nervous System Neoplasms

NCT03572530 2025-04-08

5-AZA

The University of Texas Health Science Center, Houston

Phase 1 Completed
3 enrolled

Ependymoma

NCT03206021 2024-04-05

COZMOS

The Hospital for Sick Children

Phase 1 Completed
31 enrolled
CNS

Ependymoma, Central Nervous System Neoplasms

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