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Phase

Phase 1 1

Status

Completed 3Withdrawn 1

Sponsor Class

OTHER 1

Study Type

Interventional 1

Sponsor

Cancer Type

CNS 1

Conditions

Leukemia, Myeloid, Acute 17Myelodysplastic Syndromes 8Recurrence 2Leukemia, Myelomonocytic, Chronic 2Triple Negative Breast Neoplasms 1Spinocerebellar Degenerations 1Sarcoma 1Pathologic Complete Response 1Ovarian Neoplasms 1Neoplasms, Germ Cell and Embryonal 1Neoplasm, Residual 1Melanoma 1Medulloblastoma 1Lymphoma 1Leukemia 1Graft vs Host Disease 1Ependymoma 1Colorectal Neoplasms 1Central Nervous System Neoplasms 1Carcinoma, Renal Cell 1Breast Neoplasms 1

Interventions

Magnetic Resonance Spectroscopy 3Temozolomide 2thymoglobulin 1gallium Ga 68 dotatate 1fludarabine phosphate 1Thiotepa 1Tacrolimus 1Stem Cell Transplantation 1Radiotherapy 1Nivolumab 1Mycophenolic Acid 1Methotrexate 1Melphalan 1Hematopoietic Stem Cell Transplantation 1Gadolinium DTPA 1Etoposide 1Erlotinib Hydrochloride 1Biopsy 1Bandages 1Azacitidine 1Antilymphocyte Serum 12-phenyl-6-(2'-(4'-(ethoxycarbonyl)thiazolyl))thiazolo(3,2-b)(1,2,4)triazole 1

Date Range

30 days90 days1 yearAll

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Clinical Trials

1 trials
RecentStart dateEnrollment
Withdrawn × Ependymoma × Azacitidine × Clear all
NCT06466798 2026-01-08

Fourth Ventricular Administration of Immune Checkpoint Inhibitor (Nivolumab) and Methotrexate or 5-Azacytidine for Recurrent Medulloblastoma, Ependymoma, and Other CNS Malignancies

The University of Texas Health Science Center, Houston

Phase 1 Withdrawn
CNS

Ependymoma, Medulloblastoma, Central Nervous System Neoplasms

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