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Phase

Phase 2 7Phase 1 3Phase EARLY_PHASE1 1Phase 3 1Phase 2/3 1Phase 1/2 1

Status

Withdrawn 1Recruiting 1Completed 1

Sponsor Class

OTHER 2INDUSTRY 1

Study Type

Interventional 3

Sponsor

Cancer Type

CNS 3Sarcoma 1

Conditions

Lymphoma, Large B-Cell, Diffuse 28Leukemia, Myeloid, Acute 27Precursor Cell Lymphoblastic Leukemia-Lymphoma 24Leukemia 23Lymphoma 22Small Cell Lung Carcinoma 20Burkitt Lymphoma 19Lymphoma, Non-Hodgkin 18Lung Neoplasms 13Recurrence 12Neuroblastoma 12Lymphoma, Mantle-Cell 12Leukemia, Lymphocytic, Chronic, B-Cell 12Congenital Abnormalities 12Myelodysplastic Syndromes 11Lymphoma, Follicular 11Brain Neoplasms 10Hodgkin Disease 9Carcinoma, Non-Small-Cell Lung 9Lymphoma, Large-Cell, Immunoblastic 8Lymphoma, B-Cell, Marginal Zone 8Leukemia, Myeloid, Accelerated Phase 8Leukemia, Monocytic, Acute 8Leukemia, Megakaryoblastic, Acute 8Leukemia, Erythroblastic, Acute 8Blast Crisis 8Sarcoma 7Neoplasms 7Myeloproliferative Disorders 7Multiple Myeloma 7

Interventions

Temozolomide 11Filgrastim 5Magnetic Resonance Spectroscopy 4Cyclophosphamide 4Carmustine 4Thiotepa 3Radiation 3Etoposide 3Carboplatin 3Azacitidine 3Automobiles 3sargramostim 2Radiotherapy 2Peripheral Blood Stem Cell Transplantation 2ONC206 2O(6)-benzylguanine 2Nivolumab 2Melphalan 2Immunohistochemistry 2Imiquimod 2Imatinib Mesylate 2Granulocyte Colony-Stimulating Factor 22-phenyl-6-(2'-(4'-(ethoxycarbonyl)thiazolyl))thiazolo(3,2-b)(1,2,4)triazole 22,2-dimethyl-N-(6-oxo-6,7-dihydro-5H-dibenzo(b,d)azepin-7-yl)-N'-(2,2,3,3,3-pentafluoropropyl)malonamide 21-methyltryptophan 2vitespin 1veliparib 1vatalanib 1trametinib 1thymoglobulin 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Phase 1 × Ependymoma × Etoposide × Clear all
NCT05106296 2026-01-09

Chemo-immunotherapy Using Ibrutinib Plus Indoximod for Patients With Pediatric Brain Cancer

Augusta University

Phase 1 Recruiting
37 enrolled
CNS

Brain Neoplasms, Ependymoma, Glioblastoma, Medulloblastoma, Neuroectodermal Tumors, Primitive

NCT04521946 2024-10-26

Chemotherapy and Donor Stem Transplant for the Treatment of Patients With High Grade Brain Cancer

M.D. Anderson Cancer Center

Phase 1 Withdrawn
CNS

Choroid Plexus Carcinoma, Brain Neoplasms, Ependymoma, Glioma, Medulloblastoma, Neuroectodermal Tumors, Primitive, Rhabdoid Tumor

NCT02502708 2020-06-04

Study of the IDO Pathway Inhibitor, Indoximod, and Temozolomide for Pediatric Patients With Progressive Primary Malignant Brain Tumors

Lumos Pharma

Phase 1 Completed
81 enrolled
CNSSarcoma

Diffuse Intrinsic Pontine Glioma, Brain Neoplasms, Ependymoma, Glioblastoma, Glioma, Medulloblastoma, Gliosarcoma

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