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Phase

Phase EARLY_PHASE1 2Phase 2 1Phase 1 1

Status

Completed 2

Sponsor Class

OTHER 2

Study Type

Interventional 2

Sponsor

Cancer Type

CNS 2

Conditions

Rhabdoid Tumor 2Medulloblastoma 2Ependymoma 2Brain Neoplasms 2Recurrence 1Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 1Precursor Cell Lymphoblastic Leukemia-Lymphoma 1Neurotoxicity Syndromes 1Muscle Invasive Bladder Urothelial Carcinoma 1Lymphoma, T-Cell, Peripheral 1Lymphoma, Mantle-Cell 1Lymphoma, Large B-Cell, Diffuse 1Lymphoma 1Leukemia, Large Granular Lymphocytic 1Central Nervous System Neoplasms 1Burkitt Lymphoma 1

Interventions

Radiotherapy 2Methotrexate 2fluorodopa F 18 1etoposide phosphate 1Temozolomide 1Radiation 1Perfusion Magnetic Resonance Imaging 1Magnetic Resonance Spectroscopy 1Leucovorin 1Granulocyte-Macrophage Colony-Stimulating Factor 1Gadolinium DTPA 1Etoposide 1Dynamic Contrast Enhanced Magnetic Resonance Imaging 1Diffusion Magnetic Resonance Imaging 1Biopsy 1Azacitidine 12-phenyl-6-(2'-(4'-(ethoxycarbonyl)thiazolyl))thiazolo(3,2-b)(1,2,4)triazole 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Phase EARLY_PHASE1 × Ependymoma × Methotrexate × Clear all
NCT02905110 2025-03-25

Methotrexate and Etoposide Infusions Into the Fourth Ventricle in Children with Recurrent Posterior Fossa Brain Tumors

The University of Texas Health Science Center, Houston

Phase EARLY_PHASE1 Completed
3 enrolled
CNS

Brain Neoplasms, Ependymoma, Medulloblastoma, Rhabdoid Tumor

NCT01737671 2018-01-19

Methotrexate Infusion Into the Fourth Ventricle in Children With Malignant Fourth Ventricular Brain Tumors: A Pilot Study

M.D. Anderson Cancer Center

Phase EARLY_PHASE1 Completed
7 enrolled
CNS

Brain Neoplasms, Ependymoma, Medulloblastoma, Rhabdoid Tumor

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